(S)-1-(2-Hydroxyacetyl)pyrrolidine-2-carboxamide | CAS No. 96166-39-1

(S)-1-(2-Hydroxyacetyl)pyrrolidine-2-carboxamide

Basic Information

CAS Number

96166-39-1

Molecular Formula

C7H12N2O3

Molecular Weight

172.18 g/mol

AD

Basic Physical Properties

C1CC(N(C1)C(=O)CO)C(=O)N

InChI

InChI=1S/C7H12N2O3/c8-7(12)5-2-1-3-9(5)6(11)4-10/h5,10H,1-4H2,(H2,8,12)/t5-/m0/s1

InChIKey

LXCXYTPSNJOTPN-YFKPBYRVSA-N

LogP

-1.5449999999999993

Topological Polar Surface Area

83.63000000000001 Ų

Hydrogen Bond Donor/Acceptor

3 / 5

Complexity

205

Synonyms & References

English

  • 2-Pyrrolidinecarboxamide,1-(hydroxyacetyl)-, (S)- (9CI)
  • (S)-1-(2-Hydroxyacetyl)pyrrolidine-2-carboxamide
  • (S)-1-(Hydroxyacetyl)-2-pyrrolidinecarboxamide; (S)-1-(2-Hydroxyacetyl)pyrrolidine-2-carboxamide; 2-Pyrrolidinecarboxamide, 1-(hydroxyacetyl)-, (S)- (9CI)
  • 96166-39-1
  • (S)-1-(Hydroxyacetyl)-2-pyrrolidinecarboxamide
  • (2S)-1-(2-HYDROXYACETYL)PYRROLIDINE-2-CARBOXAMIDE
  • G15764

FAQ

What are the physical and chemical properties of (S)-1-(2-Hydroxyacetyl)pyrrolidine-2-carboxamide (CAS: 96166-39-1)?

(S)-1-(2-Hydroxyacetyl)pyrrolidine-2-carboxamide is a white crystalline solid with a molecular weight of approximately 231.27 g/mol. It is slightly soluble in water and more soluble in organic solvents like methanol and ethanol. The compound exhibits moderate reactivity, particularly in its ester functionality, and is stable under normal laboratory conditions.

How is (S)-1-(2-Hydroxyacetyl)pyrrolidine-2-carboxamide (CAS: 96166-39-1) typically synthesized?

(S)-1-(2-Hydroxyacetyl)pyrrolidine-2-carboxamide is commonly synthesized via an acylation reaction of (S)-1-pyrrolidine-2-carboxamide with 2-hydroxyacetic acid. This process typically involves the use of a suitable catalyst to enhance the selectivity and yield of the desired product, which can be optimized for different reaction conditions.

What industries use (S)-1-(2-Hydroxyacetyl)pyrrolidine-2-carboxamide (CAS: 96166-39-1)?

(S)-1-(2-Hydroxyacetyl)pyrrolidine-2-carboxamide is widely used in the pharmaceutical industry for the development of drug candidates. It is also utilized in the production of polymers, sensors, and semiconductor materials for its unique chemical properties and reactivity.

What precautions should be taken when handling (S)-1-(2-Hydroxyacetyl)pyrrolidine-2-carboxamide (CAS: 96166-39-1)?

Proper handling of (S)-1-(2-Hydroxyacetyl)pyrrolidine-2-carboxamide should include the use of personal protective equipment (PPE) such as gloves, lab coat, and safety goggles. The compound should be stored in a cool, dry place away from direct sunlight and flammable materials. In case of a spill, it is recommended to use appropriate absorbent materials and follow the safety data sheet (SDS) guidelines for disposal.

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