Daprodustat | CAS No. 960539-70-2

Daprodustat

Basic Information

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CAS Number

960539-70-2

Molecular Formula

C19H27N3O6

Molecular Weight

393.44 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Surfactants Anionic Surfactants

Basic Physical Properties

Density

1.359±0.06 g/cm3 (20 ºC 760 Torr),

SMILES

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C1CCC(CC1)N2C(=O)C(C(=O)N(C2=O)C3CCCCC3)C(=O)NCC(=O)O

InChI

InChI=1S/C19H27N3O6/c23-14(24)11-20-16(25)15-17(26)21(12-7-3-1-4-8-12)19(28)22(18(15)27)13-9-5-2-6-10-13/h12-13,15H,1-11H2,(H,20,25)(H,23,24)

InChIKey

RUEYEZADQJCKGV-UHFFFAOYSA-N

LogP

1.2596

Topological Polar Surface Area

124.09000000000002 Å²

Hydrogen Bond Donor/Acceptor

2 / 9

Complexity

627

Synonyms & References

English

Daprodustat
daprodustat,GSK1278863
GSK1278863
JVR38ZM64B
N-((1,3-Dicyclohexylhexahydro-2,4,6-trioxopyrimidin-5-yl)carbonyl)glycine
(1,3-dicyclohexyl-2,4,6-trioxohexahydropyrimidine-5-carbonyl)glycine
2-[(1,3-dicyclohexyl-2,4,6-trioxo-1,3-diazinane-5-carbonyl)amino]acetic acid
Daprodustat [USAN:INN]
Daprodustat (GSK1278863)
Duvroq (TN)
GSK 1278863
Daprodustat; GSK1278863
Daprodustat (JAN/USAN/INN)
GTPL8455
BCP16766
s8171
2-[(1,3-
2-[(1,3-dicyclohexyl-2,4,6-trioxo-1,3-diazinan-5-yl)formamido]acetic acid
Duvroq
Daprodustat (GSK12
N-[(1,3-Dicyclohexylhexahydro-2,4,6-trioxo-5-pyrimidinyl)carbonyl]glycine (ACI)
Jesduvroq
N-[(1,2-Dicyclohexylhexahydro-2,4,6-trioxo-5-pyrimidinyl)carbonyl]glycine
AC-30915
CS-5453
DB11682
Daprodustat;(1,3-dicyclohexyl-2,4,6-trioxohexahydropyrimidine-5-carbonyl)glycine
DTXSID501337360
MS-26596
DB-096637
HY-17608

MDL Number

MFCD29924726

FAQ

What regulatory guidelines apply to Daprodustat (CAS: 960539-70-2)?

Daprodustat (CAS: 960539-70-2) falls under the regulatory oversight of the Globally Harmonized System of Classification and Labeling of Chemicals (GHS), REACH regulations in the EU, and FDA/EPA requirements in the United States. Manufacturers must ensure compliance with these guidelines for safety, environmental, and health aspects.

Are there alternatives to Daprodustat (CAS: 960539-70-2) in synthesis?

There are alternative reagents and synthesis methods that can be considered for Daprodustat (CAS: 960539-70-2), such as using isomers or analogs. For instance, 5-aminosalicylic acid (5-ASA) and other iron chelators are commonly explored as substitutes in research and development.

What is the market or research trend for Daprodustat (CAS: 960539-70-2)?

The market for Daprodustat (CAS: 960539-70-2) is growing due to its potential in treating chronic kidney disease and anemia. Research trends focus on its efficacy, safety, and formulation improvements. Additionally, there is increasing interest in its use as a hemoglobin-stimulating agent in various clinical settings.

How should waste containing Daprodustat (CAS: 960539-70-2) be handled?

Waste containing Daprodustat (CAS: 960539-70-2) should be collected in dedicated containers and stored under appropriate conditions to prevent environmental contamination. It is recommended to incinerate the waste or use professional waste disposal services that comply with local environmental regulations. Always consult the safety data sheet (SDS) for specific handling instructions.