Meropenem | CAS No. 96036-03-2

Meropenem

Basic Information

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CAS Number

96036-03-2

Molecular Formula

C17H25N3O5S

Molecular Weight

383.47 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Surfactants Anionic Surfactants

Basic Physical Properties

Melting Point

191-201°C

Specific Rotation

-17°--21° (c=0.44, H2O)

SMILES

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CC1C2C(C(=O)N2C(=C1SC3CC(NC3)C(=O)N(C)C)C(=O)O)C(C)O

InChI

InChI=1S/C17H25N3O5S/c1-7-12-11(8(2)21)16(23)20(12)13(17(24)25)14(7)26-9-5-10(18-6-9)15(22)19(3)4/h7-12,18,21H,5-6H2,1-4H3,(H,24,25)/t7-,8-,9+,10+,11-,12-/m1/s1

InChIKey

DMJNNHOOLUXYBV-PQTSNVLCSA-N

LogP

-0.30799999999999805

Topological Polar Surface Area

110.17999999999999 Å²

Hydrogen Bond Donor/Acceptor

3 / 8

Complexity

679

Safety Information

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Hazard Statement

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

H335 May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation

Synonyms & References

English

Meropenem
(4R,5S,6S)-3-[[(3S,5S)-5-[(Dimeth-ylamino)carbonyl]-3-pyrrolidinyl]thio]-6-[(1R)-1-hydroxyethyl]-4-methyl-7-oxo-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid
Protected Meropenem
MEROPENAM
Meropenem anhydrous
Meronem
Meropen
Merrem
Meropenemum
Antibiotic SM 7338
MEPM
Meropenemum [INN-Latin]
Meropenem [INN]
Meropenem (INN)
Meropenem Hydrate
YOP6PX0BAO
Merrem I.V.
(4r,5s,6s)-3-{[(3s,5s)-5-(Dimethylcarbamoyl)pyrrolidin-3-Yl]sulfanyl}-6-[(1r)-1-Hydroxyethyl]-4-Methyl-7-Oxo-1-Azabicyclo[3.2.0]hept-2-Ene-2-Carboxylic Acid
SM 7338
(4R,5S,6S)-3-{[(3S,5S)-5-(dimethylcarbamoyl)pyrrolidin-3-yl]thio}-6-[(1R)-1-hydroxyethy
Meropenem Trihydrate
(4R,5S,6S)-3-[[(3S,5S)-5-[(Dimethylamino)carbonyl]-3-pyrrolidinyl]thio]-6-[(1R)-1-hydroxyethyl]-4-methyl-7-oxo-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid (ACI)
1-Azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid, 3-[[5-[(dimethylamino)carbonyl]-3-pyrrolidinyl]thio]-6-(1-hydroxyethyl)-4-methyl-7-oxo-, [4R-[3(3S*,5S*),4α,5β,6β(R*)]]- (ZCI)
ICI 194660
Mepem
Meroxan
Merrem IV
Monan
(4R,5S,6S)-3-(((3S,5S)-5-(dimethylcarbamoyl)pyrrolidin-3-yl)thio)-6-((R)-1-hydroxyethyl)-4-methyl-7-oxo-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid
(6S)-2-(((3S,5S)-5-(dimethylcarbamoyl)pyrrolidin-3-yl)sulfanyl)-6-((1R)-1-hydroxyethyl)-1beta-methyl-2,3-didehydro-1-carbapenam-3-carboxylic acid
(4R,5S,6S)-3-(((3S,5S)-5-(dimethylcarbamoyl)pyrrolidin-3-yl)thio)-6-((1R)-1-hydroxyethyl)-4-methyl-7-oxo-1-azabicyclo(3.2.0)hept-2-ene-2-carboxylic acid

MDL Number

MFCD00864966

Customs Code

29419000

FAQ

What is Meropenem (CAS: 96036-03-2)?

Meropenem is a broad-spectrum carbapenem antibiotic used to treat severe bacterial infections. Its chemical formula is C18H32N2O5S, and it is known for its stability in aqueous solutions. Meropenem is effective against both Gram-positive and Gram-negative bacteria, including many drug-resistant strains. It is commonly administered intravenously and is classified as a beta-lactam antibiotic.

What are the main uses of Meropenem (CAS: 96036-03-2)?

Meropenem is primarily used in the treatment of serious bacterial infections such as sepsis, pneumonia, meningitis, and intra-abdominal infections. It is also used in hospitals for patients with compromised immune systems or those infected with multidrug-resistant organisms. As a carbapenem, Meropenem is effective in combating a wide range of pathogens, making it a key antibiotic in critical care settings.

Is Meropenem (CAS: 96036-03-2) safe?

Meropenem is generally considered safe when used as directed, but it should be handled with care to avoid adverse effects. Common side effects include gastrointestinal discomfort and allergic reactions. It is important to follow safety guidelines, such as proper dosing and administration, to minimize risks. Meropenem is approved by regulatory bodies like the FDA and is used under medical supervision to ensure patient safety.

How should Meropenem (CAS: 96036-03-2) be stored?

Meropenem should be stored in a cool, dry place at a temperature between 2°C and 8°C. It is sensitive to light and should be kept in a dark container to maintain its stability. Proper storage is essential to preserve potency and ensure effectiveness. Always check the expiration date and follow manufacturer guidelines for storage conditions.