2-Amino-1-butanol

Basic Information

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CAS Number

96-20-8

Molecular Formula

C4H11NO

Molecular Weight

89.14 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Amines

Basic Physical Properties

Melting Point

-2 °C

Boiling Point

176-178 °C

Density

0.943 g/mL at 25 °C

Refractive Index

n20/D 1.4510(lit.)

Vapor Pressure

0.3±0.7 mmHg at 25°C

SMILES

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CCC(N)CO

InChI

InChI=1S/C4H11NO/c1-2-4(5)3-6/h4,6H,2-3,5H2,1H3

InChIKey

JCBPETKZIGVZRE-UHFFFAOYSA-N

LogP

-0.2840000000000001

Topological Polar Surface Area

46.25 Å²

Hydrogen Bond Donor/Acceptor

3 / 2

Complexity

30.7

Safety Information

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GHS Hazard Pictograms

H314

Hazard Statement

H314 Causes severe skin burns and eye damage
Skin corrosion/irritation

Hazard Class

Class 8 Class 8

Sensitiveness

Air Sensitive & Hygroscopic

Synonyms & References

English

(±)-2-Amino-1-butanol
(+/-)-2-Amino-1-butanol
2-Amino-1-butanol
DL-2-Amino-1-butanol
2-Aminobutan-1-ol
2-Aminobutanol
Aminobutanol
2-AMino-n-butyl alcohol
ButanolaMine
2-Amino-1-hydroxybutane
2-Aminobutyl alcohol
1-BUTANOL, 2-AMINO-
1-Hydroxy-2-butylamine
Butanol-2-amine
1-(Hydroxymethyl)propylamine
r-(-)-2-amino-1-butanol
2-Amino-butan-1-ol
1-Butanol, 2-amino-, (S)-
JCBPETKZIGVZRE-UHFFFAOYSA-N
(+)-2-Amino-1-butanol
D-2-Amino Butanol
(+/-)-2-Amino
2-Amino-1-butanol (ACI)
(RS)-2-Amino-1-butanol
1-Hydroxy-2-aminobutane
1-Hydroxy-sec-butylamine
1-Hydroxybutan-2-amine
DL
DL-2-Aminobutanol
DL-α-Aminobutanol
dl-2-Amino-1-butanol

MDL Number

MFCD00008095

FAQ

What are the physical and chemical properties of 2-Amino-1-butanol (CAS: 96-20-8)?

2-Amino-1-butanol (CAS: 96-20-8) is a colorless, viscous liquid with a molecular weight of approximately 111.15 g/mol. It has a pKa of 8.5 and is moderately soluble in water (10 g/L at 25°C). The compound is known for its reactivity with acids and bases. It is less reactive than primary amines but more reactive than secondary amines.

How is 2-Amino-1-butanol (CAS: 96-20-8) typically synthesized?

2-Amino-1-butanol (CAS: 96-20-8) can be synthesized via the reduction of 2-bromo-1-butanol using a suitable reducing agent like sodium borohydride. Alternatively, it can be prepared by the reaction of 1-butanol with ammonia in the presence of a catalyst such as platinum or palladium on carbon. The process typically yields a mixture of isomers, and the desired 2-amino-1-butanol can be isolated by fractional distillation.

What industries use 2-Amino-1-butanol (CAS: 96-20-8)?

2-Amino-1-butanol (CAS: 96-20-8) is used in various industries. In pharmaceuticals, it serves as an intermediate in the synthesis of certain drugs. It is also utilized in the production of polymers, as a solubilizing agent, and in the development of sensors and semiconductors. Its reactivity and solubility make it a valuable compound for these applications.

What precautions should be taken when handling 2-Amino-1-butanol (CAS: 96-20-8)?

When handling 2-Amino-1-butanol (CAS: 96-20-8), it is important to use proper personal protective equipment (PPE), including gloves, goggles, and a lab coat. Work should be conducted in a well-ventilated area or a fume hood to minimize inhalation risks. Spills should be cleaned up immediately using appropriate absorbents. Consult the Safety Data Sheet (SDS) for detailed information on handling, storage, and disposal. Avoid contact with eyes, skin, and inhaling the vapors.