2-((Benzylidenehydrazono)methyl)phenol

Basic Information

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CAS Number

959-36-4

Molecular Formula

C14H12N2O

Molecular Weight

224.26 g/mol

Chemical Classification

Fine Chemicals Dyes and Pigments Organic Dyes

Basic Physical Properties

Melting Point

216.0 to 220.0 deg-C

Boiling Point

399.1℃ at 760 mmHg

Density

1.17

Water Solubility

Soluble in dimethyl sulfoxide, methanol and ethyl acetate. Slightly soluble in water.

Flash Point

256.1 °C

Solubility

Soluble in dimethyl sulfoxide, methanol and ethyl acetate. Slightly soluble in water.

Refractive Index

1.596

SMILES

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Oc1ccccc1/C=N/N=C/c1ccccc1

InChI

InChI=1S/C14H12N2O/c17-14-9-5-4-8-13(14)11-16-15-10-12-6-2-1-3-7-12/h1-11,17H/b15-10+,16-11+

InChIKey

GUVKXRKDJAEWRO-RWPWKDLBSA-N

LogP

2.845200000000001

Topological Polar Surface Area

44.95 Å²

Hydrogen Bond Donor/Acceptor

1 / 3

Complexity

496

Safety Information

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GHS Hazard Pictograms

H315

H319

H335

Hazard Statement

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

H335 May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation

Sensitiveness

对空气敏感

Synonyms & References

English

Salicylaldehyde azine
alpha,alpha-azinodi-o-cresol, of a kind used as a luminophore
Salicylaldazine
2-Hydroxybenzaldehyde azine
Salicylaldehyde Azin
Salicylalazine
alpha,alpha'-Azinodi-o-cresol
Benzaldehyde, 2-hydroxy-, [(2-hydroxyphenyl)methylene]hydrazone (9CI)
Salicylaldehyde, azine (6CI, 7CI, 8CI)
2,2′-Dihydroxybenzalazine
Bis[2-hydroxybenzaldehyde] hydrazone
N,N′-Bis(salicylidene)hydrazine
NSC 695048
NSC 864
o-Hydroxybenzaldazine
Salazine
Salicylazine
2-Hydroxybenzaldehyde Azine
2,2'-(hydrazine-1,2-diylidenebis(methanylylidene))diphenol

MDL Number

MFCD00043496

Customs Code

2928000090

FAQ

What are the physical and chemical properties of 2-((Benzylidenehydrazono)methyl)phenol (CAS: 959-36-4)?

2-((Benzylidenehydrazono)methyl)phenol is a white crystalline solid with a molecular weight of approximately 318.27 g/mol. It is slightly soluble in water but soluble in organic solvents like ethanol and dichloromethane. This compound exhibits moderate reactivity, particularly in its hydrazide group, making it susceptible to hydrolysis and reduction under certain conditions.

How is 2-((Benzylidenehydrazono)methyl)phenol (CAS: 959-36-4) typically synthesized?

2-((Benzylidenehydrazono)methyl)phenol is synthesized through a multi-step process, typically involving the condensation of benzaldehyde and hydrazine followed by coupling with phenol. This synthesis involves the use of a catalyst such as p-toluenesulfonic acid and proceeds with a yield of around 70-80%. The exact procedure can vary based on the specific method employed.

What industries use 2-((Benzylidenehydrazono)methyl)phenol (CAS: 959-36-4)?

2-((Benzylidenehydrazono)methyl)phenol is used in a variety of industries, including pharmaceuticals, where it serves as an intermediate for synthesizing other compounds. It also finds applications in polymer synthesis, where it can be used as a crosslinking agent, and in the production of sensors and semiconductors due to its electronic properties.

What precautions should be taken when handling 2-((Benzylidenehydrazono)methyl)phenol (CAS: 959-36-4)?

Handling 2-((Benzylidenehydrazono)methyl)phenol requires appropriate personal protective equipment (PPE), including gloves and safety goggles. It should be conducted in a well-ventilated area or a fume hood due to its reactivity and potential for hydrolysis. In case of spill, it should be cleaned up carefully with appropriate absorbent materials and disposed of in accordance with local regulations. Always consult a safety data sheet (SDS) for detailed handling instructions.