4'-Methoxychalcone

Basic Information

View in Editor

CAS Number

959-23-9

Molecular Formula

C16H14O2

Molecular Weight

238.29 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Ketones

Basic Chemical Raw Materials Organic Chemicals Ethers

Fine Chemicals Dyes and Pigments Organic Dyes

Fine Chemicals Surfactants Anionic Surfactants

Basic Physical Properties

Melting Point

101-103 °C

Boiling Point

397.5°Cat760mmHg

Density

1.114

Water Solubility

Soluble in dichloromethane and methanol. Insoluble in water.

Flash Point

180.5°C

Refractive Index

1.606

SMILES

View in Editor

COC1=CC=C(C=C1)C(=O)C=CC2=CC=CC=C2

InChI

InChI=1S/C16H14O2/c1-18-15-10-8-14(9-11-15)16(17)12-7-13-5-3-2-4-6-13/h2-12H,1H3

InChIKey

KJHHAPASNNVTSN-UHFFFAOYSA-N

LogP

3.591300000000002

Topological Polar Surface Area

26.3 Å²

Hydrogen Bond Donor/Acceptor

0 / 2

Complexity

282

Synonyms & References

English

4′-Methoxychalcone
2-BENZYLIDENE-4'-METHOXYACETOPHENONE
1-(4-METHOXYPHENYL)-3-PHENYLPROP-2-EN-1-ONE
(E)-1-(4-METHOXYPHENYL)-3-PHENYLPROP-2-EN-1-ONE
RARECHEM AM UC 0609
alpha-styryl p-anisyl ketone
4-Methoxychalcone
4'-Methoxychalcone
METHOXYCHALCONE, 4'-(RG)
1-(4'-methoxyphenyl)-3-phenylpropenone
benzylidene-4'-methoxyacetophenone
METHOXYCHALCONE,4'
1-(4-Methoxyphenyl)-3-phenyl-2-propen-1-one (ACI)
Chalcone, 4′-methoxy- (6CI, 7CI, 8CI)
1-(4-Methoxyphenyl)-3-phenylpropenone
1-(p-Methoxyphenyl)-3-phenyl-2-propen-1-one
4-Methoxyphenyl styryl ketone
NSC 37157
CS-0099579
TS-00699
CHALCONE, 4'-METHOXY-
1-(4-methoxyphenyl)-3-phenylprop-2-en-1-one (6)
CHEBI:174232
BM45N45FIZ
Q27274750
PD002123
S10032
LMPK12120188
SDCCGMLS-0066535.P001
NCGC00095535-04
(2E)-1-(4-Methoxyphenyl)-3-phenyl-2-propen-1-one

MDL Number

MFCD00008407

Customs Code

2914509090

FAQ

What are the physical and chemical properties of 4'-Methoxychalcone (CAS: 959-23-9)?

4'-Methoxychalcone (CAS: 959-23-9) is a yellow crystalline solid with a molecular weight of approximately 224.24 g/mol. It is sparingly soluble in water but soluble in ethanol and acetone. Chemically, it is relatively stable but can undergo photochemical degradation. It shows significant reactivity towards electrophilic aromatic substitution reactions.

How is 4'-Methoxychalcone (CAS: 959-23-9) typically synthesized?

4'-Methoxychalcone (CAS: 959-23-9) is commonly synthesized via the Claisen-Schmidt condensation of 4-methoxycinnamaldehyde and acetoacetate. The reaction involves the use of a base such as sodium hydroxide, and yields are typically around 85%. The product can be isolated by filtration and recrystallization.

What industries use 4'-Methoxychalcone (CAS: 959-23-9)?

4'-Methoxychalcone (CAS: 959-23-9) is primarily used in the pharmaceutical industry for its potential as a bioactive compound. It also finds applications in the polymer industry for its photochemical properties and in the development of sensors and semiconductors due to its electronic characteristics.

What precautions should be taken when handling 4'-Methoxychalcone (CAS: 959-23-9)?

When handling 4'-Methoxychalcone (CAS: 959-23-9), appropriate personal protective equipment such as gloves, goggles, and a lab coat should be worn. It should be stored in a cool, dark place to prevent photochemical degradation. In case of a spill, it should be carefully cleaned up using appropriate safety measures, and the Material Safety Data Sheet (MSDS) should be consulted for detailed instructions.