Benzyl 3-hydroxypyrrolidine-1-carboxylate

Basic Information

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CAS Number

95656-88-5

Molecular Formula

C12H15NO3

Molecular Weight

221.26 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Ethers

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Dyes and Pigments Organic Dyes

Fine Chemicals Surfactants Anionic Surfactants

Basic Physical Properties

Boiling Point

370.7°C at 760 mmHg

Flash Point

178℃

SMILES

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C1CN(CC1O)C(=O)OCC2=CC=CC=C2

InChI

InChI=1S/C12H15NO3/c14-11-6-7-13(8-11)12(15)16-9-10-4-2-1-3-5-10/h1-5,11,14H,6-9H2

InChIKey

MBLJFGOKYTZKMH-UHFFFAOYSA-N

LogP

1.3898000000000004

Topological Polar Surface Area

49.769999999999996 Å²

Hydrogen Bond Donor/Acceptor

1 / 4

Complexity

238

Safety Information

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Hazard Statement

H302 Harmful if swallowed
Acute toxicity, oral

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

H332 Harmful if inhaled
Acute toxicity, inhalation

H335 May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation

Synonyms & References

English

3-Hydroxy-1-N-Cbz-pyrrolidine
BENZYL 3-HYDROXYPYRROLIDINE-1-CARBOXYLATE
3-HYDROXY-PYRROLIDINE-1-CARBOXYLIC ACID BENZYL ESTER
N-CBZ-3-HYDROXYPYRROLIDINE
1-Cbz-3-hydroxypyrrolidine
1-Pyrrolidinecarboxylic acid, 3-hydroxy-, phenylmethyl ester
3-Hydroxypyrrolidine-1-carboxylic acid benzyl ester
MBLJFGOKYTZKMH-UHFFFAOYSA-N
N-(benzyloxycarbonyl)-3-pyrrolidinol
N-CBZ-3-hydroxy pyrrolidine
Benzyl 3-hydroxy-1-pyrrolidinecarboxylate
N-CBZ-3-PYRROLIDINOL
1-Cbz-3-hydroxy-pyrrolidine
1-Pyrrolidinecarboxylicacid
Phenylmethyl 3-hydroxy-1-pyrrolidinecarboxylate (ACI)
N-Benzyloxycarbonyl-3-hydroxypyrrolidine
N-Benzyloxycarbonyl-3-pyrrolidinol
benzyl 3-hydroxypyrrolidine-1-carboxylate
Benzyl 3-hydroxy-1-pyrrolidinecarboxylate #
(racemic)-N-carbobenzyloxy-3-pyrrolidinol
(R)-Benzyl 3-hydroxypyrrolidine-1-carboxylate
FS-2447
PB17468
MFCD08061949
3-hydroxypyrrolidine-1-carboxylic acid benzyl ester
AKOS012214203
1-benzyloxycarbonyl-3-hydroxypyrrolidine
N-Cbz-3-hydroxypyrrolidine
DTXSID30913871
N-benzyloxycarbonyl-3-hydroxypyrrolidine
1-PYRROLIDINECARBOXYLIC ACID, 3-HYDROXY-, PHENYLMETHYL ESTER

MDL Number

MFCD08061949

FAQ

What is Benzyl 3-hydroxypyrrolidine-1-carboxylate (CAS: 95656-88-5)?

Benzyl 3-hydroxypyrrolidine-1-carboxylate (CAS: 95656-88-5) is an organic compound with a molecular formula of C12H15NO3. It is a colorless or white solid with a distinctive odor. This compound is used primarily in pharmaceuticals and research for its potential as a bioisostere of aminoglycosides and as a chiral pool precursor in organic synthesis.

What are the main uses of Benzyl 3-hydroxypyrrolidine-1-carboxylate (CAS: 95656-88-5)?

Benzyl 3-hydroxypyrrolidine-1-carboxylate (CAS: 95656-88-5) is mainly used in pharmaceutical research as a chiral pool precursor and a bioisostere for aminoglycosides. It also finds applications in organic synthesis due to its useful structural features.

Is Benzyl 3-hydroxypyrrolidine-1-carboxylate (CAS: 95656-88-5) safe?

Benzyl 3-hydroxypyrrolidine-1-carboxylate (CAS: 95656-88-5) is generally safe when handled according to standard laboratory procedures. However, it should be used with caution, as it may cause skin irritation. It is important to wear appropriate protective equipment, including gloves and goggles, during handling. Storage in a cool, dry place away from direct sunlight is recommended.

How should Benzyl 3-hydroxypyrrolidine-1-carboxylate (CAS: 95656-88-5) be stored?

Benzyl 3-hydroxypyrrolidine-1-carboxylate (CAS: 95656-88-5) should be stored in a cool, dry place to maintain its stability. It should be protected from direct sunlight and stored in a tightly sealed container to prevent degradation. The optimal storage temperature is between 10-25°C, and humidity levels should be kept low to avoid moisture-induced changes in the compound.