Ranolazine | CAS No. 95635-55-5

Ranolazine

Basic Information

View in Editor

CAS Number

95635-55-5

Molecular Formula

C24H33N3O4

Molecular Weight

427.55 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Ethers

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Dyes and Pigments Organic Dyes

Fine Chemicals Surfactants Anionic Surfactants

Laboratory Chemicals Research Chemicals Biochemical Reagents

Basic Physical Properties

Physical State

Powder

Melting Point

119-1200C

Boiling Point

624.1°C at 760 mmHg

SMILES

View in Editor

CC1=C(C(=CC=C1)C)NC(=O)CN2CCN(CC2)CC(COC3=CC=CC=C3OC)O

InChI

InChI=1S/C24H33N3O4/c1-18-7-6-8-19(2)24(18)25-23(29)16-27-13-11-26(12-14-27)15-20(28)17-31-22-10-5-4-9-21(22)30-3/h4-10,20,28H,11-17H2,1-3H3,(H,25,29)

InChIKey

XKLMZUWKNUAPSZ-UHFFFAOYSA-N

LogP

2.30804

Topological Polar Surface Area

74.27 Å²

Hydrogen Bond Donor/Acceptor

2 / 7

Complexity

531

Safety Information

View Safety Information

Hazard Statement

H302 Harmful if swallowed
Acute toxicity, oral

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

H332 Harmful if inhaled
Acute toxicity, inhalation

H335 May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation

Synonyms & References

English

Ranolazine
1-Piperazineacetamide,N-(2,6-dimethylphenyl)-4-[2-hydroxy-3-(2-methoxyphenoxy)propyl]-
N-(2,6-dimethylphenyl)-2-[4-[2-hydroxy-3-(2-methoxyphenoxy)propyl]piperazin-1-yl]ethanamide
N-(2,6-diMethylphenyl)-2-{4-[(2R)-2-hydroxy-3-(2-Methoxyphenoxy)propyl]piperazin-1-yl}acetaMide
Ranolazine(Ranexa)
1- 3-(2-Methoxyphenoxy)-2-hydroxypropyl -4- ...
Ranolazine N-(2,6-Dimethylphenyl)-2-[4-[2-hydroxy-3-(2-methoxyphenoxy)propyl]piperazin-1-yl]acetamide
Ranolazine (100 mg)
N-(2,6-Dimethylphenyl)-2-(4-(2-hydroxy-3-(2-methoxy-phenoxy)propyl)piperazin-1-yl)acetamide
N-(2,6-Dimethylphenyl)-2-(4-(2-hydroxy-3-(2-methoxyphenoxy)propyl)piperazin-1-yl)acetamide
[14C]-Ranolazine
1-[3-(2-methoxyphenoxy)-2-hydroxypropyl]-4-[(2,6,dimethylphenyl)-aminocarbonylmethyl]-piperazine
1-[3-(2-methoxyphenoxy)-2-hydroxypropyl]-4-[(2,6-dimethylphenyl)aminocarbonylmethy]piperazine
1-Piperazineacetamide,N-(2,6-dimethylphenyl)-4-[2-hydroxy-3-(2-methoxyphenoxy)propyl]
CVT 303
N-(2,6-dimethylphenyl)-4-[2-hydroxy-3-(2-methoxyphenoxy)-propyl]-1-piperazineacetamide
Ranexa
Renexa
RS 43285-003
(±)-N-(2,6-Dimethylphenyl)-4-[2-hydroxy-3-(2-methoxyphenoxy)propyl]piperazin-1-ylacetamide
(±)-4-[2-Hydroxy-3-(o-methoxyphenoxy)propyl]-1-piperazineaceto-2′,6′-xylidide
N-(2,6-Dimethylphenyl)-2-[4-[2-hydroxy-3-(2-methoxyphenoxy)propyl]piperazin-1-yl]acetamide
Ranolazine (Ranexa)
N-(2,6-dimethylphenyl)-2-{4-[2-hydroxy-3-(2-methoxyphenoxy)propyl]piperazin-1-yl}acetamide
C24H33N3O4
DSSTox_RID_80743
DSSTox_CID_25196
DSSTox_GSID_45196
(-)-Ranolazine
Ran4
Latixa

MDL Number

MFCD00864690

Customs Code

2933990090

FAQ

What is Ranolazine (CAS: 95635-55-5)?

Ranolazine is a pharmaceutical compound with the CAS number 95635-55-5. It is a white to off-white crystalline powder, typically used in the treatment of chronic angina. Its chemical formula is C19H22N2O3, and it exhibits solubility in organic solvents. Ranolazine works by inhibiting the late sodium current in cardiac myocytes, thereby reducing myocardial oxygen demand.

What are the main uses of Ranolazine (CAS: 95635-55-5)?

Ranolazine (CAS: 95635-55-5) is primarily used to treat chronic stable angina, a condition where the heart doesn't get enough oxygen during physical activity. It is also studied for its potential in managing other cardiovascular conditions. As a drug, it is available in tablet form and is prescribed to improve exercise tolerance and reduce angina symptoms in patients with coronary artery disease.

Is Ranolazine (CAS: 95635-55-5) safe?

Ranolazine (CAS: 95635-55-5) is generally considered safe when used as directed. It has a favorable safety profile with minimal side effects, though rare cases of hypotension and dizziness may occur. Proper handling and adherence to prescribed dosages are essential to ensure safety. As with any medication, consult a healthcare professional before use.

How should Ranolazine (CAS: 95635-55-5) be stored?

Ranolazine (CAS: 95635-55-5) should be stored in a cool, dry place away from moisture and light. It is typically kept in a tightly sealed container at a temperature range of 15°C to 30°C. Avoid exposure to extreme temperatures and ensure storage conditions comply with pharmaceutical standards to maintain its stability and effectiveness.