4-(6-Bromo-3-pyridinyl)morpholine

Basic Information

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CAS Number

952582-08-0

Molecular Formula

C9H11BrN2O

Molecular Weight

243.1 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Ethers

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Agricultural Chemicals Pesticides Herbicides

Basic Physical Properties

SMILES

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C1COCCN1C2=CN=C(C=C2)Br

InChI

InChI=1S/C9H11BrN2O/c10-9-2-1-8(7-11-9)12-3-5-13-6-4-12/h1-2,7H,3-6H2

InChIKey

KXPAVTLIMQDWAW-UHFFFAOYSA-N

LogP

1.6806999999999996

Topological Polar Surface Area

25.360000000000003 Å²

Hydrogen Bond Donor/Acceptor

0 / 3

Complexity

162

Safety Information

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Hazard Statement

H302 Harmful if swallowed
Acute toxicity, oral

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

H332 Harmful if inhaled
Acute toxicity, inhalation

H335 May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation

Synonyms & References

English

A850413
CS-0036637
952582-08-0
MFCD11869572
AKOS015939674
KXPAVTLIMQDWAW-UHFFFAOYSA-N
J-513612
DS-16536
4-(6-Bromo-3-pyridyl)morpholine
AMY23078
FT-0701785
4-(6-bromopyridin-3-yl)morpholine, AldrichCPR
C9H11BrN2O
MB10311
4-(6-Bromopyridin-3-yl)morpholine
4-(6-Bromo-pyridin-3-yl)-morpholine
SCHEMBL1735452
SY015884
DTXSID40630542
2-Bromo-5-morpholinopyridine
PubChem22065
FCH1324990
BC004723
AX8164865
AB0049928
Z5398
ST24028783
4-(6-Bromo-3-pyridinyl)morpholine (ACI)
4-(6-bromopyridin-3-yl)morpholine

MDL Number

MFCD11869572

Customs Code

2934999090

FAQ

What are the physical and chemical properties of 4-(6-Bromo-3-pyridinyl)morpholine (CAS: 952582-08-0)?

4-(6-Bromo-3-pyridinyl)morpholine (CAS: 952582-08-0) is a crystalline solid with a molecular weight of approximately 247.03 g/mol. It is slightly soluble in water and has good solubility in organic solvents such as ethanol and methanol. Chemically, it is moderately reactive, showing good stability under normal conditions but can react with strong acids or bases. It is a useful intermediate in organic synthesis and pharmaceuticals.

How is 4-(6-Bromo-3-pyridinyl)morpholine (CAS: 952582-08-0) typically synthesized?

4-(6-Bromo-3-pyridinyl)morpholine (CAS: 952582-08-0) is typically synthesized through a multi-step reaction involving bromination of 3-pyridinecarboxaldehyde followed by morpholine condensation. This process uses standard laboratory equipment and involves careful control of reaction conditions to ensure high yield and selectivity. Commonly used catalysts and reagents include bromine, morpholine, and various carboxylic acids.

What industries use 4-(6-Bromo-3-pyridinyl)morpholine (CAS: 952582-08-0)?

4-(6-Bromo-3-pyridinyl)morpholine (CAS: 952582-08-0) is primarily used in the pharmaceutical industry as a precursor in the synthesis of complex organic molecules. It is also utilized in the polymer industry for modifying the properties of polymers, in sensor technology for specific chemical detection, and in semiconductor manufacturing for etching processes.

What precautions should be taken when handling 4-(6-Bromo-3-pyridinyl)morpholine (CAS: 952582-08-0)?

When handling 4-(6-Bromo-3-pyridinyl)morpholine (CAS: 952582-08-0), use appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat. Store the compound in a cool, dry place away from oxidizers and strong acids. Always work in a well-ventilated area or fume hood. In case of spill, follow the guidelines in the Material Safety Data Sheet (MSDS/SDS) for safe disposal and cleaning. It is essential to be familiar with the compound's reactivity and potential hazards before use.