(2-Oxo-1,2-dihydropyridin-3-yl)boronic acid

Basic Information

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CAS Number

951655-49-5

Molecular Formula

C5H6BNO3

Molecular Weight

138.92 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Dyes and Pigments Organic Dyes

Water Treatment Chemicals Coagulants and Flocculants Inorganic Coagulants

Basic Physical Properties

Density

1.36±0.1 g/cm3 (20 ºC 760 Torr),

SMILES

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B(C1=CC=CNC1=O)(O)O

InChI

InChI=1S/C5H6BNO3/c8-5-4(6(9)10)2-1-3-7-5/h1-3,9-10H,(H,7,8)

InChIKey

GLZIGOHMFYRHAO-UHFFFAOYSA-N

LogP

-1.9453000000000003

Topological Polar Surface Area

73.32 Å²

Hydrogen Bond Donor/Acceptor

3 / 4

Complexity

209

Synonyms & References

English

B-(1,2-dihydro-2-oxo-3-pyridinyl)-Boronic acid
(2-Oxo-1,2-dihydropyridin-3-yl)boronic acid
(2-oxo-1H-pyridin-3-yl)boronic acid
2-hydroxypyridin-3-ylboronic acid
2-Oxo-1,2-dihydropyr
2-Oxo-1,2-dihydropyridin-3-yl-boronic Acid
1,2-Dihydro-2-oxo-pyridin-3-ylboronic acid
(2-hydroxypyridin-3-yl)boronic acid
2-HYDROXYPYRIDINE-3-BORONIC ACID
2-hydroxypridine-3-boronic acid
GLZIGOHMFYRHAO-UHFFFAOYSA-N
FCH1436974
AB59785
AK120936
OR302583
BC001410
2-oxo-1,2-dihydropyridin-3-ylboronic acid
AB00
B-(1,2-Dihydro-2-oxo-3-pyridinyl)boronic acid (ACI)
(2-Hydroxypyridin-3-yl)boronic acid
(2-Oxo-1H-pyridin-3-yl)boronic acid
2-Hydroxypyridine-3-boronic acid
(2-oxo-1,2-dihydropyridin-3-yl)boronic acid
DTXSID90717034
AKOS006302942
b-(1,2-dihydro-2-oxo-3-pyridinyl)-boronic acid
SY031727
CS1662
(1,2-Dihydro-2-oxo-3-pyridinyl)boronic acid
MFCD12964572
DB-327667

MDL Number

MFCD12964572

FAQ

What are the physical and chemical properties of (2-Oxo-1,2-dihydropyridin-3-yl)boronic acid (CAS: 951655-49-5)?

(2-Oxo-1,2-dihydropyridin-3-yl)boronic acid is a white crystalline solid with a molecular weight of approximately 229.23 g/mol. It is slightly soluble in water and more soluble in organic solvents like methanol, ethanol, and DMSO. Chemically, it demonstrates moderate reactivity, particularly in boronate ester formation. Its solubility and reactivity make it useful in various synthetic and analytical applications.

How is (2-Oxo-1,2-dihydropyridin-3-yl)boronic acid (CAS: 951655-49-5) typically synthesized?

(2-Oxo-1,2-dihydropyridin-3-yl)boronic acid is typically synthesized from 2-oxo-1,2-dihydropyridine-3-carbaldehyde using boronic acid or boronic ester reagents. The reaction often involves a Suzuki coupling or similar cross-coupling reactions under mild conditions using palladium catalysts. The yield and selectivity depend on the specific reaction conditions and reagents used.

What industries use (2-Oxo-1,2-dihydropyridin-3-yl)boronic acid (CAS: 951655-49-5)?

(2-Oxo-1,2-dihydropyridin-3-yl)boronic acid is used in various industries, particularly in pharmaceuticals and fine chemicals. It serves as a versatile building block in medicinal chemistry for the synthesis of complex molecules. Additionally, it finds applications in polymer chemistry for preparing functional polymers, and in sensor technology for the development of chemical sensors due to its reactivity and solubility properties.

What precautions should be taken when handling (2-Oxo-1,2-dihydropyridin-3-yl)boronic acid (CAS: 951655-49-5)?

When handling (2-Oxo-1,2-dihydropyridin-3-yl)boronic acid, it is important to use appropriate personal protective equipment (PPE) such as gloves, goggles, and lab coat. Ensure the use of a fume hood for any operations involving air-sensitive or volatile compounds. Spills should be immediately cleaned up using appropriate absorbents and disposed of according to local regulations. Always refer to the Material Safety Data Sheet (MSDS) for specific safety guidelines and emergency procedures.