5-Amino-1,3-dihydro-2H-benzimidazol-2-one

Basic Information

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CAS Number

95-23-8

Molecular Formula

C7H7N3O

Molecular Weight

149.15 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Amines

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Dyes and Pigments Organic Dyes

Basic Physical Properties

Physical State

Powder

Melting Point

35-39°C

Boiling Point

201.4℃ at 760 mmHg

Density

1.363

Flash Point

75.6℃

Refractive Index

1.657

SMILES

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C1=CC2=C(C=C1N)NC(=O)N2

InChI

InChI=1S/C7H7N3O/c8-4-1-2-5-6(3-4)10-7(11)9-5/h1-3H,8H2,(H2,9,10,11)

InChIKey

BCXSVFBDMPSKPT-UHFFFAOYSA-N

LogP

0.43840000000000007

Topological Polar Surface Area

74.67 Å²

Hydrogen Bond Donor/Acceptor

4 / 4

Complexity

183

Safety Information

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Hazard Statement

H302 Harmful if swallowed
Acute toxicity, oral

H319 Causes serious eye irritation
Serious eye damage/eye irritation

Hazard Class

Class IRRITANT Class IRRITANT

Sensitiveness

Prone to moisture absorption; sensitive to humidity

Synonyms & References

English

5-Amino-1,3-dihydro-2H-benzimidazol-2-one
5-Aminobenzimidazolone
5-Amino-2-benzimidazolinone
5-Amino-1,3-dihydro-benzoimidazol-2-one
5-AMINOBENZOIMIDAZOLONE
2H-BENZIMIDAZOL-2-ONE,5-AMINO-1,3-DIHYDRO-
5(6)-AMINOBENZOIMIDAZOLONE
5-Amino-1,3-dihydrobenzoimidazol-2-one
5-Amino-2-benzimidazolinon
5-AMino-2-enziMidazolinone
5-AMINO-6-CHLOROBENZOIMINDAZOLONE
5-AMINOBENZIMIDAZOLIDINONE
5-AMINOBENZIMIDAZOLINONE
2-Benzimidazolinone,5-amino- (7CI,8CI)
2-Hydroxy-5-aminobenzimidazole
5-Amino-1,3-dihydrobenzimidazol-2-one
5-Amino-2(3H)-benzimidazolone
5-Amino-2-hydroxybenzimidazole
5-Amino-2-oxo-2,3-dihydro-1H-benzimidazole
2H-Benzimidazol-2-one, 5-amino-1,3-dihydro-
5-amino-1H-benzo[d]imidazol-2(3H)-one
5-amino-2,3-dihydro-1H-1,3-benzodiazol-2-one
3V3FDT3X0M
BCXSVFBDMPSKPT-UHFFFAOYSA-N
5-amino-3-hydrobenzimidazol-2-one
5-Amino-1,3-dihydro-2H-benzimidaz
2-Benzimidazolinone, 5-amino- (7CI, 8CI)
5-Amino-1,3-dihydro-2H-benzimidazol-2-one (ACI)
2-Oxo-2,3-dihydro-1H-benzimidazol-5-amine
5-Amino-1,3-dihydro-2H-benzo[d]imidazol-2-one
5-Amino-1H-benzimidazol-2(3H)-one

MDL Number

MFCD00053555

Customs Code

2933990090

FAQ

What is 5-Amino-1,3-dihydro-2H-benzimidazol-2-one (CAS: 95-23-8)?

5-Amino-1,3-dihydro-2H-benzimidazol-2-one is a chemical compound with the CAS number 95-23-8. It has the molecular formula C6H7N3O and is known for its structural features as a benzimidazole derivative. This compound is typically a white solid at room temperature and exhibits moderate solubility in polar solvents. It is commonly used as an intermediate in the synthesis of various pharmaceutical and agrochemical products.

What are the main uses of 5-Amino-1,3-dihydro-2H-benzimidazol-2-one (CAS: 95-23-8)?

5-Amino-1,3-dihydro-2H-benzimidazol-2-one is primarily used in the pharmaceutical industry as an intermediate for the production of drugs such as mebendazole, an antihelmintic medication. It also finds applications in research for developing new compounds and in agrochemicals for pesticide formulations. Additionally, it is used in industrial chemical processes and as a building block in organic synthesis.

Is 5-Amino-1,3-dihydro-2H-benzimidazol-2-one (CAS: 95-23-8) safe?

5-Amino-1,3-dihydro-2H-benzimidazol-2-one is considered relatively safe when handled properly, but it should be treated with caution. It is classified as a mild irritant to the skin and eyes, and its vapors may be harmful if inhaled. Safety standards recommend using protective gloves, goggles, and ensuring proper ventilation. It is important to follow standard chemical safety protocols to minimize exposure risks.

How should 5-Amino-1,3-dihydro-2H-benzimidazol-2-one (CAS: 95-23-8) be stored?

5-Amino-1,3-dihydro-2H-benzimidazol-2-one should be stored in a cool, dry place away from light. It is best kept in airtight containers to prevent moisture absorption and degradation. Maintaining storage conditions at temperatures below 25°C and humidity levels below 60% is recommended to ensure stability and prolong shelf life. Avoid exposure to strong oxidizing agents and keep it out of reach of children.