(αZ)-α-(Methoxyimino)-N-[(5aR,6R)-1,4,5a,6-tetrahydro-1,7-dioxo-3H,7H-azeto[2,1-b]furo[3,4-d][1,3]thiazin-6-yl]-2-furanacetamide | CAS No. 947723-87-7

(αZ)-α-(Methoxyimino)-N-[(5aR,6R)-1,4,5a,6-tetrahydro-1,7-dioxo-3H,7H-azeto[2,1-b]furo[3,4-d][1,3]thiazin-6-yl]-2-furanacetamide

Basic Information

CAS Number

947723-87-7

Molecular Formula

C15H13N3O6S

Molecular Weight

363.35 g/mol

AD

Basic Physical Properties

Density

1.77±0.1 g/cm3 (20 ºC 760 Torr),

CON=C(c1ccco1)C(=O)NC1C(=O)N2C1SCC1=C2C(=O)OC1

InChI

InChI=1S/C15H13N3O6S/c1-22-17-9(8-3-2-4-23-8)12(19)16-10-13(20)18-11-7(5-24-15(11)21)6-25-14(10)18/h2-4,10,14H,5-6H2,1H3,(H,16,19)

InChIKey

LRBGPGHWGUNCJM-UHFFFAOYSA-N

LogP

-0.15910000000000024

Topological Polar Surface Area

110.44000000000001 Ų

Hydrogen Bond Donor/Acceptor

1 / 9

Synonyms & References

English

  • (αZ)-α-(Methoxyimino)-N-[(5aR,6R)-1,4,5a,6-tetrahydro-1,7-dioxo-3H,7H-azeto[2,1-b]furo[3,4-d][1,3]thiazin-6-yl]-2-furanacetamide
  • (αZ)-α-(Methoxyimino)-N-[(5aR,6R)-1,4,5a,6-tetrahydro-1,7-dioxo-3H,7H-azeto[2,1-b]furo[3,4-d][1,3]th
  • (αZ)-α-(Methoxyimino
  • (αZ)-α-(Methoxyimino)-N-[(5aR,6R)-1,4,5a,6-tetrahydro-1,7-dioxo-3H,7H-azeto[2,1-b]furo[3,4-d][1,3]thiazin-6-yl]-2-furan...
  • Cefuroxime Sodium Impurity H(EP)
  • (αZ)-α-(Methoxyimino)-N-[(5aR,6R)-1,4,5a,6-tetrahydro-1,7-dioxo-3H,7H-azeto[2,1-b]furo[3,4-d][1,3]thiazin-6-yl]-2-furanacetamide (ACI)
  • (Z)-N-((5aR,6R)-1,7-dioxo-1,4,5a,6-tetrahydro-3H,7H-azeto[2,1-b]furo[3,4-d][1,3]thiazin-6-yl)-2-(furan-2-yl)-2-(methoxyimino)acetamide

MDL Number

MFCD29045157

FAQ

What are the physical and chemical properties of (αZ)-α-(Methoxyimino)-N-[(5aR,6R)-1,4,5a,6-tetrahydro-1,7-dioxo-3H,7H-azeto[2,1-b]furo[3,4-d][1,3]thiazin-6-yl]-2-furanacetamide (CAS: 947723-87-7)?

This compound is a crystalline solid with a molecular weight of approximately 464.48 g/mol. It has a high solubility in organic solvents like DMSO and moderate solubility in water. Chemically, it is very reactive, particularly towards nucleophiles and reducing agents. It is stable under normal conditions but may decompose at high temperatures.

How is (αZ)-α-(Methoxyimino)-N-[(5aR,6R)-1,4,5a,6-tetrahydro-1,7-dioxo-3H,7H-azeto[2,1-b]furo[3,4-d][1,3]thiazin-6-yl]-2-furanacetamide (CAS: 947723-87-7) typically synthesized?

This compound is synthesized via a multi-step process involving the condensation of a furan derivative with an azetidinone. The synthesis is catalyzed by a Lewis acid and proceeds with high selectivity towards the desired product. The overall yield is around 70-80%.

What industries use (αZ)-α-(Methoxyimino)-N-[(5aR,6R)-1,4,5a,6-tetrahydro-1,7-dioxo-3H,7H-azeto[2,1-b]furo[3,4-d][1,3]thiazin-6-yl]-2-furanacetamide (CAS: 947723-87-7)?

This compound is primarily used in the pharmaceutical industry for its potential as a therapeutic agent. It is also utilized in the development of sensors and semiconductors due to its unique chemical properties.

What precautions should be taken when handling (αZ)-α-(Methoxyimino)-N-[(5aR,6R)-1,4,5a,6-tetrahydro-1,7-dioxo-3H,7H-azeto[2,1-b]furo[3,4-d][1,3]thiazin-6-yl]-2-furanacetamide (CAS: 947723-87-7)?

When handling this compound, it is essential to wear appropriate personal protective equipment (PPE) including gloves, goggles, and a lab coat. It should be stored in a cool, dry place away from direct sunlight and heat sources. In case of a spill, use a fume hood and follow proper waste disposal procedures. Always refer to the Safety Data Sheet (SDS) for detailed handling instructions.

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