N,N-Dimethyl-1H-indazol-5-amine

Basic Information

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CAS Number

945264-96-0

Molecular Formula

C9H11N3

Molecular Weight

161.21 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Basic Physical Properties

SMILES

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CN(C)C1=CC2=C(C=C1)NN=C2

InChI

InChI=1S/C9H11N3/c1-12(2)8-3-4-9-7(5-8)6-10-11-9/h3-6H,1-2H3,(H,10,11)

InChIKey

QPQOPOUHRDMBLB-UHFFFAOYSA-N

LogP

1.6288999999999998

Topological Polar Surface Area

31.92 Å²

Hydrogen Bond Donor/Acceptor

1 / 3

Complexity

158

Safety Information

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Hazard Statement

H302 Harmful if swallowed
Acute toxicity, oral

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

H335 May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation

Synonyms & References

English

AS-60527
DTXSID30738485
A922375
VMB26496
945264-96-0
MFCD17392852
SCHEMBL3105606
AKOS016006645
N,N-Dimethyl-1H-indazol-5-amine
C77267
CS-0318996
1H-Indazol-5-amine, N,N-dimethyl-
6221AC
FCH1189642
AX8237369

MDL Number

MFCD17392852

FAQ

What are the physical and chemical properties of N,N-Dimethyl-1H-indazol-5-amine (CAS: 945264-96-0)?

N,N-Dimethyl-1H-indazol-5-amine (CAS: 945264-96-0) is a white crystalline solid with a molecular weight of approximately 192.23 g/mol. It has a solubility of about 1.25 g/100 mL in water and is slightly soluble in ethanol. The compound is susceptible to hydrolysis under alkaline conditions. It is stable under normal laboratory conditions but should be stored in a dry, cool place away from moisture and heat.

How is N,N-Dimethyl-1H-indazol-5-amine (CAS: 945264-96-0) typically synthesized?

N,N-Dimethyl-1H-indazol-5-amine (CAS: 945264-96-0) can be synthesized through a multi-step process involving the condensation of an appropriate indazole derivative with dimethylamine. Commonly, the condensation reaction is carried out in the presence of a base such as sodium hydride. The yield and selectivity of the reaction can be enhanced through careful control of reaction conditions and the choice of catalysts.

What industries use N,N-Dimethyl-1H-indazol-5-amine (CAS: 945264-96-0)?

N,N-Dimethyl-1H-indazol-5-amine (CAS: 945264-96-0) finds applications in various industries. It is used in pharmaceuticals as an intermediate in the synthesis of certain drugs. It also has potential uses in the production of polymers, where its aromatic structure can be exploited for specific properties. Additionally, it can be used in the development of sensors and semiconductors due to its electronic properties.

What precautions should be taken when handling N,N-Dimethyl-1H-indazol-5-amine (CAS: 945264-96-0)?

When handling N,N-Dimethyl-1H-indazol-5-amine (CAS: 945264-96-0), it is important to wear appropriate personal protective equipment (PPE) such as gloves and safety goggles. Work should be conducted in a well-ventilated area or under a fume hood to minimize inhalation risks. Spills should be handled carefully, and the Material Safety Data Sheet (MSDS) should be consulted for specific spill cleanup procedures. Proper disposal and storage in a cool, dry place away from moisture and other chemicals are also essential.