Jnj-38877605 | CAS No. 943540-75-8

Jnj-38877605

Basic Information

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CAS Number

943540-75-8

Molecular Formula

C19H13F2N7

Molecular Weight

377.36 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Specialty Chemicals UV Stabilizers

Agricultural Chemicals Pesticides Herbicides

Basic Physical Properties

Density

1.50

SMILES

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CN1C=C(C=N1)C2=NN3C(=NN=C3C(C4=CC5=C(C=C4)N=CC=C5)(F)F)C=C2

InChI

InChI=1S/C19H13F2N7/c1-27-11-13(10-23-27)16-6-7-17-24-25-18(28(17)26-16)19(20,21)14-4-5-15-12(9-14)3-2-8-22-15/h2-11H,1H3

InChIKey

JRWCBEOAFGHNNU-UHFFFAOYSA-N

LogP

3.2131000000000016

Topological Polar Surface Area

73.79 Å²

Hydrogen Bond Donor/Acceptor

0 / 7

Complexity

564

Safety Information

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Hazard Statement

H317 May cause an allergic skin reaction
Sensitization, Skin

H319 Causes serious eye irritation
Serious eye damage/eye irritation

Synonyms & References

English

6-[Difluoro[6-(1-methyl-1H-pyrazol-4-yl)-1,2,4-triazolo[4,3-b]pyridazin-3-yl]methyl]quinoline
6-(Difluoro(6-(1-methyl-1H-pyrazol-4-yl)-[1,2,4]-triazolo[4,3-b]pyridazin-3-yl)methyl)quinoline
6-[difluoro-[6-(1-methylpyrazol-4-yl)-[1,2,4]triazolo[4,3-b]pyridazin-3-yl]methyl]quinoline
J&J Ex-61
Quinoline, 6-[difluoro[6-(1-methyl-1H-pyrazol-4-yl)-1,2,4-triazolo[4,3-b]pyridazin-3-yl]methyl]-
JNJ-38877605
JNJ38877605
6-(difluoro(6-(1-methyl-1H-pyrazol-4-yl)-[1,2,4]triazolo[4,3-b]pyridazin-3-yl)methyl)quinoline
JNJ 38877605
15UDG410PN
C19H13F2N7
6-{difluoro[6-(1-methyl-1H-pyrazol-4-yl)[1,2,4]triazolo[4,3-b]pyridazin-3-yl]methyl}quinoline
Quinoline, 6-(difluoro(6-(1-methy
6-[Difluoro[6-(1-methyl-1H-pyrazol-4-yl)-1,2,4-triazolo[4,3-b]pyridazin-3-yl]methyl]quinoline (ACI)
AC-27418
NSC800776
JNJ 38877605?
HMS3750I11
HMS3244G09
AKOS015896605
6-{difluoro[6-(1-methylpyrazol-4-yl)-[1,2,4]triazolo[4,3-b]pyridazin-3-yl]methyl}quinoline
DB-000659
J-518058
Q27163270
HMS3295K11
US9062045, Comparator No. 1 (JNJ-38877605)
SMR004702764
NSC-800776
C77250
943540-75-8
NSC-759095

MDL Number

MFCD11977274

Customs Code

2933990090

FAQ

What are the physical and chemical properties of Jnj-38877605 (CAS: 943540-75-8)?

Jnj-38877605 is a crystalline compound with a molecular weight of approximately 591.6 g/mol. It is sparingly soluble in water and ethanol. Chemically, it is highly reactive towards nucleophiles and exhibits good stability under acidic conditions. Its solubility and reactivity make it suitable for various chemical processes.

How is Jnj-38877605 (CAS: 943540-75-8) typically synthesized?

Jnj-38877605 is synthesized via a multistep process involving the nucleophilic substitution of a protected amine with a fluorinated alkyl group. The synthesis typically employs a palladium catalyst to ensure high selectivity and yield. This method is commonly used in the pharmaceutical industry for drug development.

What industries use Jnj-38877605 (CAS: 943540-75-8)?

Jnj-38877605 is primarily used in the pharmaceutical industry for its potential as a drug candidate. It is also explored for applications in the polymer industry for its reactive properties and in the sensor industry due to its chemical reactivity.

What precautions should be taken when handling Jnj-38877605 (CAS: 943540-75-8)?

When handling Jnj-38877605, it is essential to wear appropriate personal protective equipment (PPE) including gloves, safety glasses, and a lab coat. Work should be conducted in a well-ventilated area or a fume hood. Spills should be cleaned up immediately using appropriate absorbent materials. For detailed safety information, refer to the Safety Data Sheet (SDS) for the compound.