4-(1H-Pyrazol-4-yl)-7-((2-(trimethylsilyl)ethoxy)methyl)-7H-pyrrolo[2,3-d]pyrimidine

Basic Information

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CAS Number

941685-27-4

Molecular Formula

C15H21N5OSi

Molecular Weight

315.45 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Ethers

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Basic Physical Properties

Boiling Point

501.8±50.0℃/760mmHg

Density

1.20±0.1 g/cm3 (20 ºC 760 Torr),

Solubility

Insuluble (1.0E-3 g/L) (25 ºC),

SMILES

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C[Si](C)(C)CCOCN1C=CC2=C(N=CN=C21)C3=CNN=C3

InChI

InChI=1S/C15H21N5OSi/c1-22(2,3)7-6-21-11-20-5-4-13-14(12-8-18-19-9-12)16-10-17-15(13)20/h4-5,8-10H,6-7,11H2,1-3H3,(H,18,19)

InChIKey

AVMLPTWVYQXRSV-UHFFFAOYSA-N

LogP

3.133700000000001

Topological Polar Surface Area

68.62 Å²

Hydrogen Bond Donor/Acceptor

1 / 6

Complexity

364

Safety Information

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GHS Hazard Pictograms

H302

Hazard Statement

H302 Harmful if swallowed
Acute toxicity, oral

Hazard Class

Class IRRITANT Class IRRITANT

Synonyms & References

English

4-(1H-PYRAZOL-4-YL)-7-((2-(TRIMETHYLSILYL)ETHOXY)METHYL)-7H-PYRROLO[2,3-D]PYRIMIDINE
INCB032304
trimethyl-[2-[[4-(1H-pyrazol-4-yl)pyrrolo[2,3-d]pyrimidin-7-yl]methoxy]ethyl]silane
4-(1H-pyrazol-4-yl)-7-((2-trimethylsilanylethoxy)methyl)-7H-pyrrolo[2,3-d]pyrimidine
-7-((2-(trimethylsilyl)
4-(1H-Pyrazol-4-yl)-7-[[2-(trimethylsilyl)ethoxy]methyl]-7H-pyrrolo[2,3-d]pyrimidine
4-(1H-Pyrazol-4-yl)-
4-(1H-Pyrazol-4-yl)-7-((2-(trimethylsilyl)ethoxy)-methyl)-7H-pyrrolo[2,3-d]pyrimidine
7H-Pyrrolo[2,3-d]pyrimidine, 4-(1H-pyrazol-4-yl)-7-[[2-(trimethylsilyl)ethoxy]methyl]-
4-(1H-pyrazol-4-yl)-7-(2-trimethylsilanylethoxymethyl)-7H-pyrrolo[2,3-d]pyrimidine
4-(1H-Pyrazol-4-yl)-7-[[2-(trimethylsilyl)ethoxy]methyl]-7H-pyrrolo[2,3-d]pyrimidine (ACI)
4-(1 H-Pyrazol-4-yl)-7-[2-(trimethylsilyl)ethoxy]methyl-7H-pyrrolo[2,3-d]-pyrimidine
4-(1H-Pyrazol-4-yl)-7-[2-(trimethylsilyl)ethoxy]methyl-7 H-pyrrolo[2,3-d]-pyrimidine
4-(1H-pyrazol-4-yl)-7-((2-(trimethylsilyl)ethoxy)methyl)-7H-pyrrolo[2,3-d]pyrimidine
CCG-267649
CS-M2189
4-(1H-Pyrazol-4-yl)-7-((2-(trimethylsilyl)ethoxy)methyl-7H-pyrrolo[2,3-d]pyrimidine
BCP10260
SY047224
HY-78248
4-(7-{[2-(trimethylsilyl)ethoxy]methyl}-7H-pyrrolo[2,3-d]pyrimidin-4-yl)-1H-pyrazole
4-(1H-pyrazol-4-yl)-7-{[2-(trimethylsilyl)ethoxy]methyl}-7H-pyrrolo[2,3-d]pyrimidine
AS-52590
4-(1H-pyrazol-4-yl)-7-[2-(trimethylsilyl)ethoxy]methyl-7H-pyrrolo[2,3-d]-pyrimidine
P15380
4-(7-{[2-(trimethylsilyl)ethoxy]methyl}pyrrolo[2,3-d]pyrimidin-4-yl)-1H-pyrazole
SB17825
4-(1H-pyrazol-4-yl)-7-[2-(trimethylsilyl)ethoxy]methyl-7H-pyrrolo[2,3-d]pyrimidine
s5277
941685-27-4
DTXSID10655267

MDL Number

MFCD11857754

Customs Code

2933990090

FAQ

What regulatory guidelines apply to 4-(1H-Pyrazol-4-yl)-7-((2-(trimethylsilyl)ethoxy)methyl)-7H-pyrrolo[2,3-d]pyrimidine (CAS: 941685-27-4)?

4-(1H-Pyrazol-4-yl)-7-((2-(trimethylsilyl)ethoxy)methyl)-7H-pyrrolo[2,3-d]pyrimidine (CAS: 941685-27-4) falls under the scope of the REACH regulation in the European Union, which requires registration, evaluation, authorization, and restriction of chemicals. In the United States, it is subject to the Toxic Substances Control Act (TSCA) for new chemical substances. Additionally, it should comply with Good Laboratory Practice (GLP) standards for toxicity studies and may require specific handling under the Occupational Safety and Health Administration (OSHA) regulations.

Are there alternatives to 4-(1H-Pyrazol-4-yl)-7-((2-(trimethylsilyl)ethoxy)methyl)-7H-pyrrolo[2,3-d]pyrimidine (CAS: 941685-27-4) in synthesis?

Alternatives to 4-(1H-Pyrazol-4-yl)-7-((2-(trimethylsilyl)ethoxy)methyl)-7H-pyrrolo[2,3-d]pyrimidine include various pyrimidine derivatives with different substituents, such as 5-(1H-pyrazol-4-yl)-7-(2-(trimethylsilyl)ethoxy)-7H-pyrrolo[2,3-d]pyrimidine. These alternatives can be synthesized using different reagents and conditions, such as variations of the silylation process or alternative heterocyclic precursors.

What is the market or research trend for 4-(1H-Pyrazol-4-yl)-7-((2-(trimethylsilyl)ethoxy)methyl)-7H-pyrrolo[2,3-d]pyrimidine (CAS: 941685-27-4)?

The market for 4-(1H-Pyrazol-4-yl)-7-((2-(trimethylsilyl)ethoxy)methyl)-7H-pyrrolo[2,3-d]pyrimidine (CAS: 941685-27-4) is growing due to its applications in medicinal chemistry and drug discovery. Recent research trends focus on its potential as a lead compound for antiviral and anticancer drugs. Emerging studies are exploring its synthetic versatility and biological activity, which could drive further market demand.

How should waste containing 4-(1H-Pyrazol-4-yl)-7-((2-(trimethylsilyl)ethoxy)methyl)-7H-pyrrolo[2,3-d]pyrimidine (CAS: 941685-27-4) be handled?

Waste containing 4-(1H-Pyrazol-4-yl)-7-((2-(trimethylsilyl)ethoxy)methyl)-7H-pyrrolo[2,3-d]pyrimidine (CAS: 941685-27-4) should be collected in appropriate containers and stored in a well-ventilated area. It should be disposed of through professional waste disposal services, which may involve incineration, chemical treatment, or other methods approved by environmental agencies. Proper labeling and documentation of waste management are essential to comply with regulations and ensure safety.