1-[2-(Trifluoromethyl)benzyl]piperazine | CAS No. 94022-97-6

1-[2-(Trifluoromethyl)benzyl]piperazine

Basic Information

CAS Number

94022-97-6

Molecular Formula

C12H15F3N2

Molecular Weight

244.26 g/mol

AD

Basic Physical Properties

C1CN(CCN1)CC2=CC=CC=C2C(F)(F)F

InChI

InChI=1S/C12H15F3N2/c13-12(14,15)11-4-2-1-3-10(11)9-17-7-5-16-6-8-17/h1-4,16H,5-9H2

InChIKey

MJBOPIADUICXHW-UHFFFAOYSA-N

LogP

2.1106

Topological Polar Surface Area

15.27 Ų

Hydrogen Bond Donor/Acceptor

1 / 2

Complexity

236

Synonyms & References

English

  • UNII-R8NTG95PHF
  • 1-((2-(Trifluoromethyl)phenyl)methyl)piperazine
  • 1-(2-trifluoromethyl-benzyl)-piperazine
  • 94022-97-6
  • DTXSID60240288
  • EINECS 301-592-6
  • FT-0762479
  • MFCD02633589
  • 1-[2-(TRIFLUOROMETHYL)BENZYL]PIPERAZINE
  • 1-[[2-(trifluoromethyl)phenyl]methyl]piperazine
  • NS00065302
  • 1-(2-(Trifluoromethyl)benzyl)piperazine
  • 1-[2-(trifluoromethyl)benyl]piperazine
  • R8NTG95PHF
  • 1-(2-TRIFLUOROMETHYLBENZYL)PIPERAZINE
  • AKOS009115009
  • SCHEMBL1779555
  • PIPERAZINE, 1-((2-(TRIFLUOROMETHYL)PHENYL)METHYL)-
  • F1908-2959
  • 1-[[2-(TRIFLUOROMETHYL)PHENYL]METHYL]-PIPERAZINE
  • EN300-1218523
  • 1-{[2-(Trifluoromethyl)phenyl]methyl}piperazine
  • 2-trifluoromethylbenzyl piperazine
  • 1-(2-Trifluoromethyl-benzyl)piperazine
  • 1-(2-(TRIFLUOROMETHYL)BENZYL)PIPERAZINE
  • 1-(2-Trifluoromethyl-benzyl)piperazine hydrochloride

MDL Number

MFCD02633589

FAQ

What regulatory guidelines apply to 1-[2-(Trifluoromethyl)benzyl]piperazine (CAS: 94022-97-6)?

1-[2-(Trifluoromethyl)benzyl]piperazine is regulated under the Globally Harmonized System of Classification and Labelling of Chemicals (GHS), REACH in the EU, and by the FDA and EPA in the USA. It must be labeled with appropriate hazard warnings and handled according to its identified hazards. Detailed documentation and record-keeping are required to comply with these regulations.

Are there alternatives to 1-[2-(Trifluoromethyl)benzyl]piperazine (CAS: 94022-97-6) in synthesis?

Alternatives to 1-[2-(Trifluoromethyl)benzyl]piperazine in synthesis include other piperazines with different substituents, such as 1-[2-(trifluoromethyl)phenyl]piperazine or 1-(4-fluorobenzyl)piperazine. These compounds can serve similar functions but may have different reactivity and properties.

What is the market or research trend for 1-[2-(Trifluoromethyl)benzyl]piperazine (CAS: 94022-97-6)?

The market for 1-[2-(Trifluoromethyl)benzyl]piperazine is growing due to its use in drug discovery and development, particularly in the field of GPCR modulation. Research trends indicate increasing interest in its potential therapeutic applications, driven by advancements in synthetic chemistry and biological assays.

How should waste containing 1-[2-(Trifluoromethyl)benzyl]piperazine (CAS: 94022-97-6) be handled?

Waste containing 1-[2-(Trifluoromethyl)benzyl]piperazine should be collected in appropriate containers and stored in a well-ventilated area away from ignition sources. It should be disposed of through a licensed hazardous waste management service. Environmental protection precautions include preventing spills and ensuring proper incineration or chemical treatment to mitigate environmental impact.

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