(AC-TYR1,D-ARG2)-GRF (1-29) AMIDE (HUMAN) | CAS No. 93942-91-7

(AC-TYR1,D-ARG2)-GRF (1-29) AMIDE (HUMAN)

Basic Information

CAS Number

93942-91-7

Molecular Formula

C154H255N47O43S

Molecular Weight

3485.03 g/mol

AD

Basic Physical Properties

Density

1.45±0.1 g/cm3 (20 ºC 760 Torr),

[C@H](C(=O)N[C@@H]([C@H](O)C)C(=O)N[C@@H](CC(=O)N)C(=O)N[C@@H](CO)C(=O)N[C@H](C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CC(C)C)C(=O)NCC(=O)N[C@@H](CCC(=O)N)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CO)C(=O)N[C@@H](C)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCC(=O)N)C(=O)N[C@@H](CC(=O)O)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CCSC)C(=O)N[C@@H](CO)C(=O)N[C@H](C(=O)N)CCCNC(N)=N)CC1C=CC(O)=CC=1)(NC(=O)[C@H]([C@@H](C)CC)NC(=O)[C@H](C)NC(=O)[C@H](CC(=O)O)NC(=O)[C@@H](CCCNC(N)=N)NC(=O)[C@@H](NC(=O)C)CC1C=CC(O)=CC=1)CC1C=CC=CC=1

InChI

1S/C154H255N47O43S/c1-20-80(13)120(199-125(219)83(16)174-135(229)108(69-117(213)214)190-130(224)96(40-32-59-172-154(167)168)182-139(233)104(176-85(18)206)66-87-41-45-89(207)46-42-87)149(243)193-106(65-86-33-23-22-24-34-86)142(236)201-122(84(17)205)150(244)194-107(68-115(159)211)141(235)197-112(74-204)146(240)189-105(67-88-43-47-90(208)48-44-88)140(234)183-95(39-31-58-171-153(165)166)128(222)181-93(36-26-28-55-156)134(228)198-119(79(11)12)147(241)192-100(61-75(3)4)126(220)173-71-116(212)177-97(49-51-113(157)209)131(225)187-103(64-78(9)10)138(232)196-110(72-202)144(238)175-82(15)124(218)179-94(38-30-57-170-152(163)164)127(221)180-92(35-25-27-54-155)129(223)186-102(63-77(7)8)137(231)188-101(62-76(5)6)136(230)184-98(50-52-114(158)210)132(226)191-109(70-118(215)216)143(237)200-121(81(14)21-2)148(242)185-99(53-60-245-19)133(227)195-111(73-203)145(239)178-91(123(160)217)37-29-56-169-151(161)162/h22-24,33-34,41-48,75-84,91-112,119-122,202-205,207-208H,20-21,25-32,35-40,49-74,155-156H2,1-19H3,(H2,157,209)(H2,158,210)(H2,159,211)(H2,160,217)(H,173,220)(H,174,229)(H,175,238)(H,176,206)(H,177,212)(H,178,239)(H,179,218)(H,180,221)(H,181,222)(H,182,233)(H,183,234)(H,184,230)(H,185,242)(H,186,223)(H,187,225)(H,188,231)(H,189,240)(H,190,224)(H,191,226)(H,192,241)(H,193,243)(H,194,244)(H,195,227)(H,196,232)(H,197,235)(H,198,228)(H,199,219)(H,200,237)(H,201,236)(H,213,214)(H,215,216)(H4,161,162,169)(H4,163,164,170)(H4,165,166,171)(H4,167,168,172)/t80-,81-,82-,83-,84+,91-,92-,93-,94-,95-,96+,97-,98-,99-,100-,101-,102-,103-,104-,105-,106-,107-,108-,109-,110-,111-,112-,119-,120-,121-,122-/m0/s1

InChIKey

JIFMAFJPNLVLAC-UBKPBUPGSA-N

LogP

-14.928420000000182

Topological Polar Surface Area

1511.879999999999 Ų

Hydrogen Bond Donor/Acceptor

65 / 90

Complexity

290

Synonyms & References

English

  • 1-29-Somatoliberin(human pancreatic islet), N-acetyl-2-D-arginine-29-L-argininamide- (9CI)
  • Acetyl-(D-Arg²)-GRF (1-29) amide (human)
  • Acetyl-(D-Arg2)-GRF (1-29) amide (human), Acetyl-(D-Arg2)-Sermorelin
  • ACETYL-(TYR1,D-ARG2)-GRF (1-29) AMIDE (HUMAN)
  • AC-TYR-DARG-ASP-ALA-ILE-PHE-THR-ASN-SER-TYR-ARG-LYS-VAL-LEU-GLY-GLN-LEU-SER-ALA-ARG-LYS-LEU-LEU-GLN-ASP-ILE-MET-SER-ARG-NH2
  • GROWTH HORMONE RELEASING FACTOR [N-ACETYL-TYR1,D-ARG2]-FRAGMENT 1-29 AMIDE HUMAN
  • somatotropin releasing hormone (1-29)amide, N-acetyl-tyrosyl(1)-arginyl(2)-
  • Acetyl-(Tyr1,D-Arg2)-GRF (1-29) aMide (huMan) Acetyl-(Tyr1,D-Arg2)-SerMorelin
  • Acetyl-(Tyr1,D-Arg2)-SerMorelin
  • Acetyl-(D-Arg2)-GRF (1-29) amide (human)
  • AC-[DARG2] GHRF (1-29), AMIDE, HUMAN
  • AC-[DARG2] GROWTH HORMONE RELEASING FACTOR (1-29), AMIDE, HUMAN
  • AC-TYR-D-ARG-ASP-ALA-ILE-PHE-THR-ASN-SER-TYR-ARG-LYS-VAL-LEU-GLY-GLN-LEU-SER-ALA-ARG-LYS-LEU-LEU-GLN-ASP-ILE-MET-SER-ARG-NH2
  • Somatoliberin (human pancreatic islet), N-acetyl-2-D-arginine-29-L-argininamide-30-de-L-glutamine-31-de-L-glutamine-32-deglycine-33-de-L-glutamic acid-34-de-L-serine-35-de-L-asparagine-36-de-L-glutamine-37-de-L-glutamic acid-38-de-L-arginine-39-deglycine-40-de-L-alanine-41-de-L-arginine-42-de-L-alanine-43-de-L-arginine-44-de-L-leucinamide- (ZCI)
  • D
  • L

MDL Number

MFCD00079960

FAQ

What regulatory guidelines apply to (AC-TYR1,D-ARG2)-GRF (1-29) AMIDE (HUMAN) (CAS: 93942-91-7)?

The regulatory guidelines for (AC-TYR1,D-ARG2)-GRF (1-29) AMIDE (HUMAN) (CAS: 93942-91-7) include GHS classification for hazardous chemicals, REACH regulations for the European market, and FDA/EPA requirements for safety and environmental protection. It is crucial to comply with these regulations to ensure the safe handling, transportation, and disposal of the compound.

Are there alternatives to (AC-TYR1,D-ARG2)-GRF (1-29) AMIDE (HUMAN) in synthesis?

There are several alternatives to (AC-TYR1,D-ARG2)-GRF (1-29) AMIDE (HUMAN) in synthesis, including other growth hormone releasing peptides (GHRPs) like [other GHRPs]. Common alternative reagents include different amino acid sequences or isomers. However, these alternatives may have different potency and efficacy profiles, and it is essential to evaluate their suitability for specific applications.

What is the market or research trend for (AC-TYR1,D-ARG2)-GRF (1-29) AMIDE (HUMAN) (CAS: 93942-91-7)?

The market and research trend for (AC-TYR1,D-ARG2)-GRF (1-29) AMIDE (HUMAN) (CAS: 93942-91-7) shows increasing interest in its potential for treating conditions such as growth hormone deficiency and obesity. Recent studies focus on optimizing formulations and delivery methods to enhance bioavailability and efficacy. The trend indicates growing research and development efforts to explore its therapeutic potential.

How should waste containing (AC-TYR1,D-ARG2)-GRF (1-29) AMIDE (HUMAN) be handled?

Waste containing (AC-TYR1,D-ARG2)-GRF (1-29) AMIDE (HUMAN) (CAS: 93942-91-7) should be handled by collecting it in a sealed container and disposing of it according to local hazardous waste regulations. Incineration or professional waste disposal services are recommended to ensure environmental safety. It is essential to follow all safety precautions and comply with relevant regulations to prevent environmental contamination and ensure worker safety.

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