N-Formyl Amlodipine

Basic Information

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CAS Number

93848-81-8

Molecular Formula

C21H25ClN2O6

Molecular Weight

436.89 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Esters

Basic Chemical Raw Materials Organic Chemicals Ethers

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Dyes and Pigments Organic Dyes

Fine Chemicals Surfactants Anionic Surfactants

Agricultural Chemicals Pesticides Herbicides

Laboratory Chemicals Research Chemicals Biochemical Reagents

Basic Physical Properties

Melting Point

Not available

Boiling Point

599.7±50.0 °C at 760 mmHg

Density

1.2±0.1 g/cm3

Flash Point

316.5±30.1 °C

Vapor Pressure

0.0±1.7 mmHg at 25°C

SMILES

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CCOC(=O)C1=C(NC(=C(C1c2ccccc2Cl)C(=O)OC)C)COCCNC=O

InChI

InChI=1S/C21H25ClN2O6/c1-4-30-21(27)19-16(11-29-10-9-23-12-25)24-13(2)17(20(26)28-3)18(19)14-7-5-6-8-15(14)22/h5-8,12,18,24H,4,9-11H2,1-3H3,(H,23,25)

InChIKey

XEJRHYXNQHVXRJ-UHFFFAOYSA-N

LogP

2.0536

Topological Polar Surface Area

102.96000000000001 Å²

Hydrogen Bond Donor/Acceptor

2 / 8

Synonyms & References

English

N-Fomyl Amlodipine
N-Formyl Amlodipine
3-Ethyl 5-Methyl 4-(2-Chlorophenyl)-2-(2-formamidoethoxymethyl)-6-methyl-1,4-dihydropyridine-3,5-dicarboxylate (N-Formylamlodipine)
3-Ethyl 5-methyl 4-(2-chlorophenyl)-2-[[2-(formylamino)ethoxy]methyl]-1,4-dihydro-6-methyl-3,5-pyridinedicarboxylate (ACI)
3-Ethyl 5-methyl 4-(2-chlorophenyl)-2-((2-formamidoethoxy)methyl)-6-methyl-1,4-dihydropyridine-3,5-dicarboxylate
3-ethyl 5-methyl 4-(2-chlorophenyl)-2-((2-formamidoethoxy)methyl)-6-methyl-1,4-dihydropyridine-3,5-dicarboxylate

MDL Number

MFCD21363413

FAQ

What regulatory guidelines apply to N-Formyl Amlodipine (CAS: 93848-81-8)?

N-Formyl Amlodipine (CAS: 93848-81-8) is subject to regulatory guidelines such as GHS (Global Harmonized System of Classification and Labeling of Chemicals) for classification and hazard communication, REACH (Registration, Evaluation, Authorization and Restriction of Chemicals) for safety data sheets and risk management, and FDA/EPA guidelines for drug and environmental safety. Compliance with these regulations is essential for its safe and legal handling and distribution.

Are there alternatives to N-Formyl Amlodipine (CAS: 93848-81-8) in synthesis?

Alternatives to N-Formyl Amlodipine (CAS: 93848-81-8) in synthesis include using dihydropyridine derivatives with different functional groups, such as amlodipine itself without the formyl group. Other substitutes like other calcium channel blockers with similar properties can also be considered, depending on the specific requirements of the synthesis process.

What is the market or research trend for N-Formyl Amlodipine (CAS: 93848-81-8)?

The market and research trends for N-Formyl Amlodipine (CAS: 93848-81-8) are largely driven by its role as a derivative of amlodipine, which is a widely used calcium channel blocker. Research is focusing on its potential applications in drug development and understanding its mechanism of action. Market trends suggest increasing interest in derivatives and analogs for improving efficacy and reducing side effects.

How should waste containing N-Formyl Amlodipine (CAS: 93848-81-8) be handled?

Waste containing N-Formyl Amlodipine (CAS: 93848-81-8) should be collected in appropriate containers and disposed of through professional waste disposal services to ensure safety and environmental protection. Proper handling includes minimizing exposure and ensuring all waste is treated according to local regulations. Incineration may be a preferred method for disposal, but it should be conducted in a controlled and regulated manner to prevent environmental contamination.