2-Hydroxybenzohydrazide

Basic Information

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CAS Number

936-02-7

Molecular Formula

C7H8N2O2

Molecular Weight

152.15 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Amines

Fine Chemicals Dyes and Pigments Organic Dyes

Basic Physical Properties

Melting Point

148.0 to 152.0 deg-C

Boiling Point

274.61°C (rough estimate)

Density

1.2804 (rough estimate)

Refractive Index

1.5200 (estimate)

SMILES

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C1=CC=C(C(=C1)C(=O)NN)O

InChI

InChI=1S/C7H8N2O2/c8-9-7(11)5-3-1-2-4-6(5)10/h1-4,10H,8H2,(H,9,11)

InChIKey

XSXYESVZDBAKKT-UHFFFAOYSA-N

LogP

-0.00430000000000047

Topological Polar Surface Area

75.35000000000001 Å²

Hydrogen Bond Donor/Acceptor

4 / 4

Complexity

149

Safety Information

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Hazard Statement

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

Hazard Class

Class IRRITANT Class IRRITANT

Synonyms & References

English

Salicylhydrazide
Salicylic acid hydrazide
salicylic hydrazide
Salicyloyl hydrazide
salicylohydrazide
2-Hydroxybenzhydrazide
o-Hydroxybenzoylhydrazine
2-Hydroxybenzoic hydrazide
2-hydroxybenzohydrazide
2-hydroxybenzene-1-carbohydrazide
Propylenethiourea Solution
Salicyl hydrazide
Salicyloylhydrazine
o-Hydroxybenzhydrazide
o-Hydroxybenzoylhydrazide
2-Hydroxybenzoylhydrazide
2-Hydroxybenzoylhydrazine
o-Hydroxylbenzhydrazide
Salicyclohydrazine
Salicoyl hydrazide
o-Hydroxybenzoic acid hydrazide
2-Hydroxybenzoic acid hydrazide
SALICYLIC ACID, HYDRAZIDE
Salicycic acid hydrazide
B
Salicylic acid, hydrazide (6CI, 7CI, 8CI)
2-Hydroxybenzene-1-carbohydrazide
2-Hydroxybenzene-1-carbohydrazonic acid
2-Hydroxybenzenecarboxylic acid hydrazide
2-Hydroxybenzohydrazide
2-Hydroxybenzoyl hydrazide

MDL Number

MFCD00007599

Customs Code

2928000090

FAQ

What regulatory guidelines apply to 2-Hydroxybenzohydrazide (CAS: 936-02-7)?

2-Hydroxybenzohydrazide (CAS: 936-02-7) is regulated under the Globally Harmonized System of Classification and Labelling of Chemicals (GHS), which includes handling, storage, and transportation guidelines. In the European Union, it falls under the REACH regulation, which requires registration of substances above one tonne per year. The U.S. Food and Drug Administration (FDA) and Environmental Protection Agency (EPA) may also impose additional requirements for its use and disposal.

Are there alternatives to 2-Hydroxybenzohydrazide (CAS: 936-02-7) in synthesis?

Alternative reagents to 2-Hydroxybenzohydrazide (CAS: 936-02-7) include other hydrazones and related compounds. For example, 2-Amino-4-hydroxyacetophenone and 2-Hydroxyacetophenone are often used as substitutes in similar synthetic pathways. These alternatives can provide similar functional groups for further chemical transformations.

What is the market or research trend for 2-Hydroxybenzohydrazide (CAS: 936-02-7)?

The market for 2-Hydroxybenzohydrazide (CAS: 936-02-7) is growing due to its applications in the development of pharmaceuticals, dyes, and materials science. Recent research trends focus on its use as an intermediate in the synthesis of various compounds, particularly in the field of anticancer drugs and organic pigments. The demand is expected to increase with ongoing research and development in these areas.

How should waste containing 2-Hydroxybenzohydrazide (CAS: 936-02-7) be handled?

Waste containing 2-Hydroxybenzohydrazide (CAS: 936-02-7) should be collected in appropriate containers and disposed of as hazardous waste. Incineration is a common disposal method, but professional waste disposal services are recommended to ensure compliance with local regulations. Environmental protection measures include neutralizing any acidic or alkaline residues before disposal to prevent environmental contamination.