cis-1,2,3,6-Tetrahydrophthalic anhydride | CAS No. 935-79-5

Q: What is cis-1,2,3,6-Tetrahydrophthalic anhydride (CAS: 935-79-5)?

Cis-1,2,3,6-Tetrahydrophthalic anhydride (CAS: 935-79-5) is a cyclic anhydride derived from phthalic acid. Its chemical formula is C8H6O3. It is a colorless to pale yellow liquid with a characteristic odor, known for its reactivity and use as an intermediate in organic synthesis. It exhibits moderate solubility in water and is typically stored under controlled conditions to maintain stability.

Q: What are the main uses of cis-1,2,3,6-Tetrahydrophthalic anhydride (CAS: 935-79-5)?

Cis-1,2,3,6-Tetrahydrophthalic anhydride (CAS: 935-79-5) is widely used in the pharmaceutical industry for the synthesis of various drugs. It also finds applications in the production of polymers, coatings, and other industrial materials. In research, it serves as a versatile reagent for organic reactions. Its use in food-related applications is limited due to potential regulatory restrictions.

Q: Is cis-1,2,3,6-Tetrahydrophthalic anhydride (CAS: 935-79-5) safe?

Cis-1,2,3,6-Tetrahydrophthalic anhydride (CAS: 935-79-5) is considered hazardous and requires careful handling. It may cause skin and eye irritation, and inhalation can lead to respiratory issues. Safety standards recommend using appropriate personal protective equipment (PPE) and ensuring proper ventilation. It should be handled in accordance with OSHA and EPA guidelines to minimize exposure risks.

Q: How should cis-1,2,3,6-Tetrahydrophthalic anhydride (CAS: 935-79-5) be stored?

Cis-1,2,3,6-Tetrahydrophthalic anhydride (CAS: 935-79-5) should be stored in a cool, dry, and well-ventilated area, away from light and moisture. It is recommended to keep it in a sealed, non-reactive container, such as a glass or stainless steel vessel, to maintain its chemical stability and prevent degradation. Storage should also follow safety regulations to avoid contact with incompatible substances.

cis-1,2,3,6-Tetrahydrophthalic anhydride

Basic Information

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CAS Number

935-79-5

Molecular Formula

C8H8O3

Molecular Weight

152.15 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Esters

Basic Chemical Raw Materials Organic Chemicals Ethers

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Basic Physical Properties

Melting Point

101.0 to 104.0 deg-C

Boiling Point

234.6°C (rough estimate)

Density

1.2143 (rough estimate)

Refractive Index

1.4447 (estimate)

Vapor Pressure

<0.01 mmHg ( 20 °C)

SMILES

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C1C=CCC2C1C(=O)OC2=O

InChI

InChI=1S/C8H8O3/c9-7-5-3-1-2-4-6(5)8(10)11-7/h1-2,5-6H,3-4H2/t5-,6+

InChIKey

KMOUUZVZFBCRAM-OLQVQODUSA-N

LogP

0.6522

Topological Polar Surface Area

43.370000000000005 Å²

Hydrogen Bond Donor/Acceptor

0 / 3

Complexity

218

Safety Information

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GHS Hazard Pictograms

H317

H318

H334

H412

Hazard Statement

H317 May cause an allergic skin reaction
Sensitization, Skin

H318 Causes serious eye damage
Serious eye damage/eye irritation

H334 May cause allergy or asthma symptoms or breathing difficulties if inhaled
Sensitization, respiratory

H412 Harmful to aquatic life with long lasting effects
Hazardous to the aquatic environment, long-term hazard

Hazard Class

Class 8 Class 8

Sensitiveness

Moisture Sensitive

Synonyms & References

English

(3aR,7aS)-rel-3a,4,7,7a-tetrahydroisobenzofuran-1,3-dione
1,2,3,6-TETRAHYDROPHTHALIC ANHYDRIDE
3A,4,7,7A-TETRAHYDRO-2-BENZOFURAN-1,3-DIONE
4-CYCLOHEXENE-1,2-DICARBOXYLIC ANHYDRIDE
CIS-1,2,3,6-TETRAHYDROPHTHALIC ANHYDRIDE
CIS-4-CYCLOHEXEN-1,2-DIMETHANOIC ANHYDRIDE
CIS-4-CYCLOHEXENE-1,2-DICARBOXYLIC ANHYDRIDE
CIS-4-TETRAHYDROPHTHALIC ANHYDRIDE
CIS-DELTA4-TETRAHYDROPHTHALIC ANHYDRIDE
CIS-THPA
TETRAHYDROPHTHALIC ANHYDRIDE
THPA
1,3-isobenzofurandion,3a,4,7,7a-tetrahydro-,cis-
3-Isobenzofurandione,3a,4,7,7a-tetrahydro-,cis-1
4,7,7a-tetrahydro-3-isobenzofurandioncis-3a
cis-3a,4,7,7a-Tetrahydro-1,3-isobenzofurandione
(cis)-1,2,3,6-Tetrahydrophthalic anhydride
Four hydrogen of benzene anhydride
(3aS,7aR)-3a,4,7,7a-tetrahydro-2-benzofuran-1,3-dione
cis-tetrahydrophthalic anhydride
cis-Δ4-Tetrahydrophthalic Anhydride
1,3-Isobenzofurandione, 3a,4,7,7a-tetrahydro-, cis- (ZCI)
4-Cyclohexene-1,2-dicarboxylic anhydride, cis- (8CI)
rel-(3aR,7aS)-3a,4,7,7a-Tetrahydro-1,3-isobenzofurandione (ACI)
cis-1,2,3,6-Tetrahydrophthalic acid anhydride
cis-1,2,3,6-Tetrahydrophthalic anhydride
cis-4-Cyclohexene-1,2-dicarboxylic acid anhydride
cis-4-Cyclohexene-1,2-dicarboxylic anhydride
cis-Δ4-Tetrahydrophthalic anhydride
meso-1,2,3,6-Tetrahydrophthalic anhydride
NSC 49672

MDL Number

MFCD00005916

FAQ

What is cis-1,2,3,6-Tetrahydrophthalic anhydride (CAS: 935-79-5)?

Cis-1,2,3,6-Tetrahydrophthalic anhydride (CAS: 935-79-5) is a cyclic anhydride derived from phthalic acid. Its chemical formula is C8H6O3. It is a colorless to pale yellow liquid with a characteristic odor, known for its reactivity and use as an intermediate in organic synthesis. It exhibits moderate solubility in water and is typically stored under controlled conditions to maintain stability.

What are the main uses of cis-1,2,3,6-Tetrahydrophthalic anhydride (CAS: 935-79-5)?

Cis-1,2,3,6-Tetrahydrophthalic anhydride (CAS: 935-79-5) is widely used in the pharmaceutical industry for the synthesis of various drugs. It also finds applications in the production of polymers, coatings, and other industrial materials. In research, it serves as a versatile reagent for organic reactions. Its use in food-related applications is limited due to potential regulatory restrictions.

Is cis-1,2,3,6-Tetrahydrophthalic anhydride (CAS: 935-79-5) safe?

Cis-1,2,3,6-Tetrahydrophthalic anhydride (CAS: 935-79-5) is considered hazardous and requires careful handling. It may cause skin and eye irritation, and inhalation can lead to respiratory issues. Safety standards recommend using appropriate personal protective equipment (PPE) and ensuring proper ventilation. It should be handled in accordance with OSHA and EPA guidelines to minimize exposure risks.

How should cis-1,2,3,6-Tetrahydrophthalic anhydride (CAS: 935-79-5) be stored?

Cis-1,2,3,6-Tetrahydrophthalic anhydride (CAS: 935-79-5) should be stored in a cool, dry, and well-ventilated area, away from light and moisture. It is recommended to keep it in a sealed, non-reactive container, such as a glass or stainless steel vessel, to maintain its chemical stability and prevent degradation. Storage should also follow safety regulations to avoid contact with incompatible substances.