Glimepiride | CAS No. 93479-97-1

Glimepiride

Basic Information

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CAS Number

93479-97-1

Molecular Formula

C24H34N4O5S

Molecular Weight

490.63 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Dyes and Pigments Organic Dyes

Fine Chemicals Surfactants Anionic Surfactants

Laboratory Chemicals Research Chemicals Biochemical Reagents

Basic Physical Properties

Physical State

Powder

Melting Point

202.0 to 206.0 deg-C

Boiling Point

No data available

Density

1.29

Flash Point

No data available

Solubility

DMSO: >10 mg/mL

Refractive Index

1.599

SMILES

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CCC1=C(CN(C1=O)C(=O)NCCC2=CC=C(C=C2)S(=O)(=O)NC(=O)NC3CCC(CC3)C)C

InChI

InChI=1S/C24H34N4O5S/c1-4-21-17(3)15-28(22(21)29)24(31)25-14-13-18-7-11-20(12-8-18)34(32,33)27-23(30)26-19-9-5-16(2)6-10-19/h7-8,11-12,16,19H,4-6,9-10,13-15H2,1-3H3,(H,25,31)(H2,26,27,30)/t16-,19-

InChIKey

WIGIZIANZCJQQY-RUCARUNLSA-N

LogP

2.785700000000001

Topological Polar Surface Area

124.68 Å²

Hydrogen Bond Donor/Acceptor

3 / 9

Complexity

895

Safety Information

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GHS Hazard Pictograms

H361

Hazard Statement

H361 Suspected of damaging fertility or the unborn child
Reproductive toxicity

Synonyms & References

English

Glimepiride
glimepirid
hoe490
1-[[p-[2-(3-ethyl-4-methyl-2-oxo-3-pyrroline-1-carboxamido)ethyl]phenyl]sulfonyl]-3-(trans-4-methylcyclohexyl)urea
amary
AMARYL
Glimperide
CLIMEPIRIDE
GliMepiride COS
Glimpiride
Grimepride
trans-3-Ethyl-2,5-dihydro-4-methyl-N-[N-[4-[[[[(4-methylcyclohexyl)amino]carbonyl]amino]sulfonyl]phenyl]ethyl]-2-oxo-1H-pyrrole-1-carboxamide
HOE-490
Glimepiride impurity
Amarel
Glimepiridum
Glimepirida
Endial
Glimepride
cis-Glimepiride
Glimepiridum [Latin]
HOE 490
Glimepirida [Spanish]
Glista OD
4-ethyl-3-methyl-N-[2-[4-[(4-methylcyclohexyl)carbamoylsulfamoyl]phenyl]ethyl]-5-oxo-2H-pyrrole-1-carboxamide
1-((p-(2-(3-Ethyl-4-methyl-2-oxo-3-pyrroline-1-carboxamido)ethyl)phenyl)sulfonyl)-3-(trans-4-methylcyclohexyl)urea
24T6XIR2MZ
1H-Pyrrole-1-carboxamide, 3-ethyl-2,5-dihydro-4-methyl-N-[2-[4-[[[[(4-methylcyclohexyl)amino]carbonyl]amino]sulfonyl]phenyl]ethyl]-2-oxo-, trans- (ZCI)
3-Ethyl-2,5-dihydro-4-methyl-N-[2-[4-[[[[(trans-4-methylcyclohexyl)amino]carbonyl]amino]sulfonyl]phenyl]ethyl]-2-oxo-1H-pyrrole-1-carboxamide (ACI)
Amaryl
Diameprid

MDL Number

MFCD00878417

Customs Code

2935009090

FAQ

What is Glimepiride (CAS: 93479-97-1)?

Glimepiride (CAS: 93479-97-1) is a sulfonylurea derivative used primarily in medicine. Its chemical formula is C15H16N4O4S, and it appears as a white crystalline powder. It is highly soluble in water and has a molecular weight of 372.39 g/mol. Glimepiride functions as a hypoglycemic agent, stimulating insulin release from pancreatic beta cells. It is commonly prescribed for managing type 2 diabetes by improving glucose metabolism. Its chemical structure and properties make it effective in regulating blood sugar levels.

What are the main uses of Glimepiride (CAS: 93479-97-1)?

Glimepiride (CAS: 93479-97-1) is mainly used as an antidiabetic medication to treat type 2 diabetes. It works by binding to ATP-sensitive potassium channels in pancreatic cells, enhancing insulin secretion. Additionally, it is employed in research for studying glucose regulation mechanisms. Its applications in pharmaceuticals focus on improving glycemic control. Glimepiride is also used in industrial settings for drug formulation and synthesis processes.

Is Glimepiride (CAS: 93479-97-1) safe?

Glimepiride (CAS: 93479-97-1) is generally safe when used as directed under medical supervision. Common side effects include hypoglycemia, weight gain, and gastrointestinal discomfort. It should be handled with care, avoiding direct skin contact and inhalation. Proper disposal is essential to prevent environmental contamination. Safety standards require adherence to regulatory guidelines, such as those from the FDA, to ensure therapeutic efficacy and minimize risks.

How should Glimepiride (CAS: 93479-97-1) be stored?

Glimepiride (CAS: 93479-97-1) should be stored in a cool, dry place away from light. Maintain temperature between 15°C to 25°C (59°F to 77°F) and keep humidity low to preserve stability. Use airtight containers to prevent moisture absorption. Avoid exposure to incompatible substances like strong acids. Proper storage ensures potency and safety, as recommended by chemical and pharmaceutical guidelines.