3-Bromo-5-fluorobenzamide | CAS No. 933585-20-7

3-Bromo-5-fluorobenzamide

Basic Information

CAS Number

933585-20-7

Molecular Formula

C7H5BrFNO

Molecular Weight

218.03 g/mol

AD

Basic Physical Properties

C1=C(C=C(C=C1F)Br)C(=O)N

InChI

InChI=1S/C7H5BrFNO/c8-5-1-4(7(10)11)2-6(9)3-5/h1-3H,(H2,10,11)

InChIKey

CFWMRENFPXKUBG-UHFFFAOYSA-N

LogP

1.6871

Topological Polar Surface Area

43.09 Ų

Hydrogen Bond Donor/Acceptor

2 / 2

Complexity

165

Synonyms & References

English

  • Z406681428
  • CHEMBL4980139
  • 933585-20-7
  • 3-BROMO-5-FLUOROBENZAMIDE
  • TS-03117
  • DTXSID70655783
  • AKOS009396979
  • SCHEMBL12607365
  • QC-7896

MDL Number

MFCD07780673

Customs Code

2924299090

FAQ

What regulatory guidelines apply to 3-Bromo-5-fluorobenzamide (CAS: 933585-20-7)?

3-Bromo-5-fluorobenzamide (CAS: 933585-20-7) is classified as a hazardous chemical under the Globally Harmonized System of Classification and Labelling of Chemicals (GHS). It falls under the category of gases under pressure and has specific handling and storage guidelines. In the European Union, it is regulated under REACH, requiring manufacturers and importers to register substances if their annual manufacturing or importing quantity exceeds one tonne. The FDA and EPA also have specific requirements for the handling and disposal of this compound due to its potential toxicity and environmental impact.

Are there alternatives to 3-Bromo-5-fluorobenzamide (CAS: 933585-20-7) in synthesis?

While 3-Bromo-5-fluorobenzamide (CAS: 933585-20-7) is a specific compound, there are alternative reagents that can be used in similar synthesis processes. For example, 3-Fluorobenzamide and 3-Bromobenzamide are common alternatives. Additionally, using other functional group manipulations such as using 5-fluorobenzamide and brominating it directly can be a viable alternative. These alternatives can provide similar reactivity while potentially being easier to handle or less toxic.

What is the market or research trend for 3-Bromo-5-fluorobenzamide (CAS: 933585-20-7)?

The market for 3-Bromo-5-fluorobenzamide (CAS: 933585-20-7) is driven by its application in pharmaceutical research, particularly in the development of analgesics and anti-inflammatory drugs. Recent research trends indicate a growing interest in its use as a precursor for medicinal chemistry due to its unique pharmacological properties. However, demand is also influenced by the increasing focus on sustainable and greener synthetic routes. The price trend for this compound shows variability, influenced by supply chain disruptions and changes in raw material availability.

How should waste containing 3-Bromo-5-fluorobenzamide (CAS: 933585-20-7) be handled?

Waste containing 3-Bromo-5-fluorobenzamide (CAS: 933585-20-7) should be managed according to the guidelines set by local environmental protection agencies and the waste should be collected in a sealed, leak-proof container. The waste should be disposed of through a professional hazardous waste disposal service to ensure compliance with regulatory standards. Proper incineration or chemical treatment is necessary to neutralize any residual bromine and fluorine compounds. Environmental protection precautions include the use of personal protective equipment and ensuring proper ventilation during handling and disposal.

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