5-Aminouracil

Basic Information

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CAS Number

932-52-5

Molecular Formula

C4H5N3O2

Molecular Weight

127.1 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Amines

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Dyes and Pigments Organic Dyes

Water Treatment Chemicals Coagulants and Flocculants Inorganic Coagulants

Basic Physical Properties

Physical State

Powder

Melting Point

>300 °C

Boiling Point

235.85°C (rough estimate)

Density

1.4748 (rough estimate)

Water Solubility

0.5 g/L (20 ºC)

Flash Point

262.2 °C

Refractive Index

1.5000 (estimate)

SMILES

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C1=C(C(=O)NC(=O)N1)N

InChI

InChI=1S/C4H5N3O2/c5-2-1-6-4(9)7-3(2)8/h1H,5H2,(H2,6,7,8,9)

InChIKey

BISHACNKZIBDFM-UHFFFAOYSA-N

LogP

-1.3546000000000002

Topological Polar Surface Area

91.74000000000001 Å²

Hydrogen Bond Donor/Acceptor

4 / 5

Complexity

196

Safety Information

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GHS Hazard Pictograms

H302

Hazard Statement

H302 Harmful if swallowed
Acute toxicity, oral

Synonyms & References

English

5-Aminopyrimidine-2,4(1H,3H)-dione
5-AMINO-2,4-DIHYDROXYPYRIMIDINE[5-2,6]
5-AMINO-2,4-PYRIMIDINEDIOL
5-AMINOURACIL
2,4(1H,3H)-Pyrimidinedione, 5-amino-
2,4-Dihydroxy-5-aminopyrimidine
3h)-pyrimidinedione,5-amino-4(1h
5-Amino-2,4(1H,3H)-pyrimidinedione
5-amino-uraci
Uracil, 5-amino-
2,4(1H,3H)-Pyrimidinedione, 5-amino- (9CI)
5-Amino-2,4-dihydroxypyrimidine, 5-Amino-2,4-pyrimidinediol
5-Amino-1H-pyrimidine-2,4-dione
-Amino-2,4-pyrimidinediol
5-Amino-1H-pyrimidin-2,4-dion
5-Amino-2,4-dihydroxypyrimidine
5-aminouracyl
EINECS 213-252-3
URACIL,5-AMINO
5-aminopyrimidine-2,4-diol
R2O7EKY9G9
BISHACNKZIBDFM-UHFFFAOYSA-N
5-amino uracil
WBU
5-amino-1,3-dihydropyrimidine-2,4-dione
Uracil, 5-amino- (VAN)
2,4-dioxo-5-aminopyrimidine
5-Amino-2,4(1H,3H)-pyrimidinedione (ACI)
Uracil, 5-amino- (6CI, 8CI)
5-Amino-2,4-pyrimidinediol
5-Aminouracil

MDL Number

MFCD00006025

Customs Code

2933599090

FAQ

What are the physical and chemical properties of 5-Aminouracil (CAS: 932-52-5)?

5-Aminouracil (CAS: 932-52-5) is a crystalline solid with a molecular weight of approximately 123.12 g/mol. It has a solubility of about 4 g/100 mL in water and is slightly soluble in ethanol. Chemically, it is reactive towards bases and oxidizing agents. It is used in organic synthesis and pharmaceuticals due to its reactivity.

How is 5-Aminouracil (CAS: 932-52-5) typically synthesized?

5-Aminouracil (CAS: 932-52-5) is typically synthesized by reduction of 5-chlorouracil with sodium borohydride or lithium aluminum hydride. The reaction is carried out in a solvent like ethanol, with yield around 75-85%. The product is purified by recrystallization from water or ethanol.

What industries use 5-Aminouracil (CAS: 932-52-5)?

5-Aminouracil (CAS: 932-52-5) is primarily used in the pharmaceutical industry for the synthesis of antiviral drugs. It also finds applications in the research of DNA and RNA, as well as in the development of semiconductors and polymers.

What precautions should be taken when handling 5-Aminouracil (CAS: 932-52-5)?

When handling 5-Aminouracil (CAS: 932-52-5), ensure the use of personal protective equipment (PPE) such as gloves, goggles, and lab coat. Work in a well-ventilated hood to minimize inhalation of dust. Store in a dry, cool place away from direct sunlight. In the event of a spill, neutralize with an acid or base and dispose of according to local regulations. Refer to the Safety Data Sheet (SDS) for detailed information.