o-Tolylmagnesium Bromide

Basic Information

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CAS Number

932-31-0

Molecular Formula

C7H7BrMg

Molecular Weight

195.34 g/mol

Chemical Classification

Agricultural Chemicals Pesticides Herbicides

Basic Physical Properties

Density

1.013 g/mL at 25 °C

Flash Point

−40 °F

SMILES

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CC1=CC=CC=[C-]1.[Mg+2].[Br-]

InChI

InChI=1S/C7H7.BrH.Mg/c1-7-5-3-2-4-6-7;;/h2-5H,1H3;1H;/q;;+1/p-1

InChIKey

DVXDIGKNJYSMFM-UHFFFAOYSA-M

LogP

1.63442

Topological Polar Surface Area

0.0 Å²

Hydrogen Bond Donor/Acceptor

0 / 0

Complexity

145

Safety Information

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GHS Hazard Pictograms

H225

H302

H314

H335

H371

H372

Hazard Statement

H225 Highly Flammable liquid and vapor
Flammable liquids

H302 Harmful if swallowed
Acute toxicity, oral

H314 Causes severe skin burns and eye damage
Skin corrosion/irritation

H335 May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation

H371 May cause damage to organs
Specific target organ toxicity, single exposure

H372 Causes damage to organs through prolonged or repeated exposure
Specific target organ toxicity, repeated exposure

Hazard Class

Class 3/8 Class 3/8

Sensitiveness

Sensitive to moisture and air

Synonyms & References

English

Magnesium,bromo(2-methylphenyl)-
(O)-Tolylmagnesium bromide solution
magnesium,methylbenzene,bromide
O-TOLYLMAGNESIUM BROMIDE
O-TOLYLMAGNESIUM BROMIDE 1M THF
o-Tolylmagnesium Bromide, 1.0 M solution in THF, SpcSeal
o-Tolylmagnesium bromide, 2.0 M solution in diethyl ether, in resealable bottle
2.0 M solution in diethyl ether ,MkSeal
2-Methylphenylmagnesium bromide
2-TOLYL MAGNESIUM BROMIDE
o-TolylMagnesiuM broMide solution
-Tolylmagnesium bromide solution
Bromo-o-tolylmagnesium
2-Tolylmagnesium bromide
bromo(2-methylphenyl)magnesium
o-Methylphenylmagnesium bromide
o-tolyl magnesium bromide
C7H7BrMg
o-Tolylmagnesium bromide, 2M solution in diethyl ether, AcroSeal(R)
tolylmagnesium bromide
o-Tolylmagnesiumbromid
toluylmagnesium bromide
bromo(o-tolyl)magnesium
o-tolyl-magnesiumbromide
2-toluylmagnesium bromide
o-toluyl magnesium bromid
Bromo(2-methylphenyl)magnesium (ACI)
Magnesium, bromo-o-tolyl- (7CI, 8CI)
o-Tolylmagnesium bromide (6CI)
Ortho-methylphenylmagnesium bromide
EINECS 213-250-2

MDL Number

MFCD00010350

Customs Code

2931900090

FAQ

What regulatory guidelines apply to o-Tolylmagnesium Bromide (CAS: 932-31-0)?

o-Tolylmagnesium Bromide (CAS: 932-31-0) is subject to various regulatory guidelines including GHS classification, REACH regulations, and FDA/EPA requirements. This compound is classified as a flammable liquid and requires appropriate handling and storage under GHS. Under REACH, it must be registered with the European Chemicals Agency, and in the USA, it is regulated by the EPA for environmental protection. Regulatory compliance is essential to ensure safe handling and disposal of this compound.

Are there alternatives to o-Tolylmagnesium Bromide (CAS: 932-31-0) in synthesis?

There are several alternatives to o-Tolylmagnesium Bromide (CAS: 932-31-0) in synthesis, including other Grignard reagents and organolithium compounds. Common alternatives include tert-Butyllithium and sec-Butyllithium, which offer similar functionality but with different handling and reactivity profiles. These alternatives can be chosen based on the specific synthesis requirements, such as reactivity and synthetic utility.

What is the market or research trend for o-Tolylmagnesium Bromide (CAS: 932-31-0)?

o-Tolylmagnesium Bromide (CAS: 932-31-0) is in steady demand within the pharmaceutical, fine chemical, and polymer synthesis industries. Recent research trends focus on its application in organic synthesis, particularly in the formation of C-C bonds and the modification of aromatic rings. Market trends suggest a consistent demand, with ongoing exploration into its use in innovative chemical processes and drug development.

How should waste containing o-Tolylmagnesium Bromide (CAS: 932-31-0) be handled?

Waste containing o-Tolylmagnesium Bromide (CAS: 932-31-0) should be handled with care due to its flammability and reactivity. Collection should be done in a closed container to prevent contact with air. The waste should then be neutralized and disposed of using professional waste disposal services, ensuring compliance with local environmental regulations. Additional precautions include proper storage and labeling to prevent accidental exposure or reaction.