Methyl nicotinate

Basic Information

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CAS Number

93-60-7

Molecular Formula

C7H7NO2

Molecular Weight

137.14 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Esters

Basic Chemical Raw Materials Organic Chemicals Ethers

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Dyes and Pigments Organic Dyes

Basic Physical Properties

Melting Point

39-42 °C<br />42-44 °C

Boiling Point

204 °C

Density

1.2528 (rough estimate)

Solubility

H2O: 0.1 g/mL, clear

Refractive Index

1.5323 (estimate)

SMILES

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COC(=O)c1cccnc1

InChI

InChI=1S/C7H7NO2/c1-10-7(9)6-3-2-4-8-5-6/h2-5H,1H3

InChIKey

YNBADRVTZLEFNH-UHFFFAOYSA-N

LogP

0.8681999999999999

Topological Polar Surface Area

39.19 Å²

Hydrogen Bond Donor/Acceptor

0 / 3

Complexity

125

Safety Information

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GHS Hazard Pictograms

H315

H319

H335

Hazard Statement

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

H335 May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation

Synonyms & References

English

Methyl nicotinate
Methyl pyridine-3-carboxylate
Nicotinic acid methyl ester
3-Picolinic acid methyl ester
3-methoxycarbonylpyridine
3-pyridinecarboxylic acid methyl ester
FEMA 3709
methyl 3-nicotinate
methyl 3-pyridinecarboxylate
Methyl nictinate
methylnicotinicacid
NIACIN METHYL ESTER
Nicometh
Nikomet
pyridine-3-carboxylic acid methyl ester
Methylnicotinate
Methyl-nicotinate
3-Pyridinecarboxylic acid, methyl ester
Nicotinic acid, methyl ester
3-(Carbomethoxy)pyridine
Heat spray
3-(Methoxycarbonyl)pyridine
m-(Methoxycarbonyl)pyridine
3-Picolinic acid methyl ester
3PyrCOOMe
Heat spray (TN)
FEMA No. 3709
3-Carbomethoxypyridine
Methyl nicotinat
Nicotinic acid, methyl ester (6CI, 7CI, 8CI)
Methyl 3-pyridinecarboxylate

MDL Number

MFCD00006388

Customs Code

2936290090

FAQ

What is Methyl nicotinate (CAS: 93-60-7)?

Methyl nicotinate is a chemical compound with the formula C8H9N1O2. It is a clear, colorless liquid with a mild, slightly sweet odor. This compound is derived from nicotinic acid and is commonly used in various industries due to its solubility in water and organic solvents. It is also known as 3-methoxy-1,2,3-trihydroxy-5-methylpyridine.

What are the main uses of Methyl nicotinate (CAS: 93-60-7)?

Methyl nicotinate is primarily used in pharmaceuticals as a dermal absorption enhancer and in the formulation of topical medications. It also finds applications in the food industry as a flavoring agent and in the production of certain pesticides. In research, it serves as a precursor for other nicotinic acid derivatives and is used in studies related to skin permeation and drug delivery systems.

Is Methyl nicotinate (CAS: 93-60-7) safe?

Methyl nicotinate is generally considered safe when used as directed, but it should be handled with care. It may cause skin irritation or sensitization upon prolonged exposure. Proper protective equipment, such as gloves and goggles, is recommended during handling. Safety data sheets (SDS) should be consulted for detailed guidelines on exposure limits and emergency procedures.

How should Methyl nicotinate (CAS: 93-60-7) be stored?

Methyl nicotinate should be stored in a cool, dry, and well-ventilated area, away from direct sunlight. It is stable under normal conditions but should be kept in a sealed container to prevent moisture absorption. Storage at temperatures below 25°C is recommended, and it should be kept out of reach of children and incompatible materials to ensure long-term safety and efficacy.