6-Fluorospiro[3,1-benzoxazine-4,4'-piperidin]-2(1H)-one | CAS No. 92926-32-4

6-Fluorospiro[3,1-benzoxazine-4,4'-piperidin]-2(1H)-one

Basic Information

CAS Number

92926-32-4

Molecular Formula

C12H13FN2O2

Molecular Weight

236.25 g/mol

AD

Basic Physical Properties

Density

1.35

C1CNCCC12C3=C(C=CC(=C3)F)NC(=O)O2

InChI

InChI=1S/C12H13FN2O2/c13-8-1-2-10-9(7-8)12(17-11(16)15-10)3-5-14-6-4-12/h1-2,7,14H,3-6H2,(H,15,16)

InChIKey

ZHRWOWCJMFGREP-UHFFFAOYSA-N

LogP

1.9665

Topological Polar Surface Area

50.36 Ų

Hydrogen Bond Donor/Acceptor

2 / 4

Complexity

318

Synonyms & References

English

  • 6-FLUOROSPIRO[4H-3,1-BENZOXAZINE-4,4`-PIPERIDIN]-2(1H)-ONE
  • 6-Fluorospiro[4H-3,1-benzoxazine-4,4'-piperidin]-2(1H)-one
  • CS-0028237
  • 6-fluoro-1,2-dihydrospiro[3,1-benzoxazine-4,4'-piperidine]-2-one
  • FT-0718438
  • SB43143
  • 6-fluorospiro[3,1-benzoxazine-4,4'-piperidin]-2(1h)-one
  • 92926-32-4
  • 6-fluorospiro[1H-3,1-benzoxazine-4,4'-piperidine]-2-one
  • DTXSID10519234
  • AKOS005145777
  • DS-0356
  • EN300-7366376
  • Spiro[4H-3,1-benzoxazine-4,4'-piperidin]-2(1H)-one, 6-fluoro-
  • 6-Fluorospiro[4H-3 pound not1-benzoxazine-4 pound not4'-piperidin]-2(1H)-one
  • 6-fluorospiro[benzo[d][1,3]oxazine-4,4'-piperidin]-2(1H)-one
  • (6-Fluorospiro[4H-3,1-benzoxazine-4,4'-piperidin]-2(1H)-one)
  • SCHEMBL631308
  • BR-
  • 6-fluoro-1,2-dihydrospiro[3,1-benzoxazine-4,4'-piperidin]-2-one

MDL Number

MFCD10566063

Customs Code

2934999090

FAQ

What are the physical and chemical properties of 6-Fluorospiro[3,1-benzoxazine-4,4'-piperidin]-2(1H)-one (CAS: 92926-32-4)?

6-Fluorospiro[3,1-benzoxazine-4,4'-piperidin]-2(1H)-one (CAS: 92926-32-4) is a crystalline solid with a molecular weight of approximately 291.18 g/mol. It is sparingly soluble in water but more soluble in organic solvents like ethanol and acetonitrile. Its chemical reactivity is moderate, with good stability under normal conditions but can react with strong acids and bases. It has a low reactivity with most metals and is not flammable.

How is 6-Fluorospiro[3,1-benzoxazine-4,4'-piperidin]-2(1H)-one (CAS: 92926-32-4) typically synthesized?

6-Fluorospiro[3,1-benzoxazine-4,4'-piperidin]-2(1H)-one (CAS: 92926-32-4) can be synthesized via a multi-step process involving the condensation of 2,3-dihydro-1H-benzimidazol-2-one with 1,4-dihydro-4-oxo-1-piperidinecarboxylic acid. Common catalysts include imidazole, and the reaction typically yields a high purity product with excellent selectivity. The overall yield can range from 60% to 80% depending on the reaction conditions.

What industries use 6-Fluorospiro[3,1-benzoxazine-4,4'-piperidin]-2(1H)-one (CAS: 92926-32-4)?

6-Fluorospiro[3,1-benzoxazine-4,4'-piperidin]-2(1H)-one (CAS: 92926-32-4) finds applications in the pharmaceutical industry for the synthesis of complex organic molecules and as an intermediate. It is also used in the polymer industry for the development of advanced materials. Additionally, it has potential applications in sensor technology and semiconductor manufacturing due to its unique chemical properties.

What precautions should be taken when handling 6-Fluorospiro[3,1-benzoxazine-4,4'-piperidin]-2(1H)-one (CAS: 92926-32-4)?

When handling 6-Fluorospiro[3,1-benzoxazine-4,4'-piperidin]-2(1H)-one (CAS: 92926-32-4), it is important to wear appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat. The compound should be handled in a well-ventilated area or a fume hood to prevent inhalation. Spills should be cleaned up using appropriate absorbent materials, and the area should be thoroughly ventilated. Refer to the Safety Data Sheet (SDS) for detailed information on handling and storage procedures.

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