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(R)-5-(6-((4-methylpiperazin-1-yl)methyl)-1H-benzo[d]imidazol-1-yl)-3-(1-(2-(trifluoromethyl)phenyl)ethoxy)thiophene-2-carboxamide | CAS No. 929095-18-1

(R)-5-(6-((4-methylpiperazin-1-yl)methyl)-1H-benzo[d]imidazol-1-yl)-3-(1-(2-(trifluoromethyl)phenyl)ethoxy)thiophene-2-carboxamide

Basic Information

Chemical_Structure_Of
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CAS Number

929095-18-1

Molecular Formula

C27H28F3N5O2S

Molecular Weight

543.62 g/mol

AD

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids
Basic Chemical Raw Materials Organic Chemicals Ethers
Basic Chemical Raw Materials Organic Chemicals Amines
Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds
Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates
Fine Chemicals Dyes and Pigments Organic Dyes
Fine Chemicals Surfactants Anionic Surfactants
Fine Chemicals Specialty Chemicals UV Stabilizers
Agricultural Chemicals Pesticides Herbicides
Laboratory Chemicals Research Chemicals Biochemical Reagents

Basic Physical Properties

Boiling Point

658°C at 760 mmHg

Density

1.39

SMILES

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CC(C1=CC=CC=C1C(F)(F)F)OC2=C(SC(=C2)N3C=NC4=C3C=C(C=C4)CN5CCN(CC5)C)C(=O)N

InChI

InChI=1S/C27H28F3N5O2S/c1-17(19-5-3-4-6-20(19)27(28,29)30)37-23-14-24(38-25(23)26(31)36)35-16-32-21-8-7-18(13-22(21)35)15-34-11-9-33(2)10-12-34/h3-8,13-14,16-17H,9-12,15H2,1-2H3,(H2,31,36)/t17-/m1/s1

InChIKey

ZHJGWYRLJUCMRT-QGZVFWFLSA-N

LogP

5.092100000000005

Topological Polar Surface Area

76.62 Ų

Hydrogen Bond Donor/Acceptor

2 / 7

Complexity

814

Safety Information

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Hazard Statement

H302 Harmful if swallowed
Acute toxicity, oral
H315 Causes skin irritation
Skin corrosion/irritation
H319 Causes serious eye irritation
Serious eye damage/eye irritation
H335 May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation

Synonyms & References

English

  • 5-[6-[(4-Methyl-1-piperazinyl)methyl]-1H-benzimidazol-1-yl]-3-[(1R)-1-[2-(trifluoromethyl)phenyl]ethoxy]-2-Thiophenecarboxamide
  • GSK-461364A
  • (R)-5-(6-((4-methylpiperazin-1-yl)methyl)-1H-benzo[d]imidazol-1-yl)-3-(1-(2-(trifluoromethyl)phenyl)ethoxy)thiophene-2-carboxamide
  • GSK461364
  • (R)-5-(6-((4-METHYLPIPERAZIN-1-YL)METHYL)-1H-BENZO[D]IMIDAZOL-1-YL)-3-(1-(2-(TRIFLUOROMETHYL)PHENYL)ETHOXY)THIOPHENE-2-...
  • 5-[6-[(4-Methyl-1-piperazinyl)methyl]-1H-benzimidazol-1-yl]-3-[(1R)-1-[2-(trifluoromethyl)phenyl]ethoxy]-2-thiophenecar...
  • 5-[6-[(4-methylpiperazin-1-yl)methyl]benzimidazol-1-yl]-3-[(1R)-1-[2-(trifluoromethyl)phenyl]ethoxy]thiophene-2-carboxamide
  • GSK-461364
  • GSK461364 (GSK-461364)
  • GSK461364A
  • GSK 461364
  • 8QO27TK6Q4
  • ZHJGWYRLJUCMRT-QGZVFWFLSA-N
  • GTPL5684
  • C27H28F3N5O2S
  • BCP01720
  • Z
  • 5-[6-[(4-Methyl-1-piperazinyl)methyl]-1H-benzimidazol-1-yl]-3-[(1R)-1-[2-(trifluoromethyl)phenyl]ethoxy]-2-thiophenecarboxamide (ACI)
  • 5-[6-[(4-Methylpiperazin-1-yl)methyl]-1H-benzimidazol-1-yl]-3-[[(1R)-1-[2-(trifluoromethyl)phenyl]ethyl]oxy]thiophene-2-carboxamide
  • GSK 461364A
  • GLXC-10075
  • DTXSID60239197
  • SW220052-1
  • GSK 461364 [WHO-DD]
  • 2-Thiophenecarboxamide, 5-(6-((4-methyl-1-piperazinyl)methyl)-1H-benzimidazol-1-yl)-3-((1R)-1-(2-(trifluoromethyl)phenyl)ethoxy)-
  • NSC-800111
  • Q27077906
  • SCHEMBL310080
  • UNII-8QO27TK6Q4
  • BDBM50355500
  • CS-0069

MDL Number

MFCD12755419

FAQ

What is (R)-5-(6-((4-methylpiperazin-1-yl)methyl)-1H-benzo[d]imidazol-1-yl)-3-(1-(2-(trifluoromethyl)phenyl)ethoxy)thiophene-2-carboxamide (CAS: 929095-18-1)?
This compound is a complex organic molecule with a unique chemical structure. It contains thiophene, benzo[d]imidazole, and piperazine functional groups. It is primarily used in the pharmaceutical industry for its potential therapeutic effects.

What are the main uses of (R)-5-(6-((4-methylpiperazin-1-yl)methyl)-1H-benzo[d]imidazol-1-yl)-3-(1-(2-(trifluoromethyl)phenyl)ethoxy)thiophene-2-carboxamide (CAS: 929095-18-1)?
The main use of this compound is in the development of new drugs, particularly in the area of antipsychotics and mood stabilizers. It is also explored for its potential in cancer and neurodegenerative disease research.

Is (R)-5-(6-((4-methylpiperazin-1-yl)methyl)-1H-benzo[d]imidazol-1-yl)-3-(1-(2-(trifluoromethyl)phenyl)ethoxy)thiophene-2-carboxamide (CAS: 929095-18-1) safe?
While safety data is limited, this compound generally requires proper handling and storage. It should be handled in a fume hood and appropriate personal protective equipment should be used to minimize exposure. Careful follow-up studies are necessary to fully assess its long-term safety.

How should (R)-5-(6-((4-methylpiperazin-1-yl)methyl)-1H-benzo[d]imidazol-1-yl)-3-(1-(2-(trifluoromethyl)phenyl)ethoxy)thiophene-2-carboxamide (CAS: 929095-18-1) be stored?
This compound should be stored in a cool, dry place away from direct sunlight and moisture. It should be kept in a tightly sealed container to prevent degradation. Optimal storage conditions are below 25°C and with minimal exposure to humidity and light to maintain its stability and efficacy.

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HANGZHOU RUYAN MEDICAL TECHNOLOGY CO., LTD.

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(R)-5-(6-((4-methylpiperazin-1-yl)methyl)-1H-benzo[d]imidazol-1-yl)-3-(1-(2-(trifluoromethyl)phenyl)ethoxy)thiophene-2-carboxamide — Hubei Yunmei Technology Co., Ltd.

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(R)-5-(6-((4-methylpiperazin-1-yl)methyl)-1H-benzo[d]imidazol-1-yl)-3-(1-(2-(trifluoromethyl)phenyl)ethoxy)thiophene-2-carboxamide — Jin Jinle (Hunan) Chemical Co., Ltd.

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(R)-5-(6-((4-methylpiperazin-1-yl)methyl)-1H-benzo[d]imidazol-1-yl)-3-(1-(2-(trifluoromethyl)phenyl)ethoxy)thiophene-2-carboxamide — Hubei Nona Technology Co., Ltd.

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(R)-5-(6-((4-methylpiperazin-1-yl)methyl)-1H-benzo[d]imidazol-1-yl)-3-(1-(2-(trifluoromethyl)phenyl)ethoxy)thiophene-2-carboxamide — ShangHaiJiZhiShengHua Technology Co Ltd

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