2-(3-aminophenoxy)-N-phenylacetamide

Basic Information

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CAS Number

92906-39-3

Molecular Formula

C14H14N2O2

Molecular Weight

242.28 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Ethers

Basic Chemical Raw Materials Organic Chemicals Amines

Fine Chemicals Dyes and Pigments Organic Dyes

Fine Chemicals Surfactants Anionic Surfactants

Basic Physical Properties

Melting Point

123-124 ºC

Density

1.254

SMILES

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C1=CC=C(C=C1)NC(=O)COC2=CC=CC(=C2)N

InChI

InChI=1S/C14H14N2O2/c15-11-5-4-8-13(9-11)18-10-14(17)16-12-6-2-1-3-7-12/h1-9H,10,15H2,(H,16,17)

InChIKey

UKKALNOCJIYBPA-UHFFFAOYSA-N

LogP

2.2862999999999998

Topological Polar Surface Area

64.35 Å²

Hydrogen Bond Donor/Acceptor

3 / 4

Complexity

265

Synonyms & References

English

L10070
DTXSID801280152
AMY10519
AKOS000154226
2-(3-aminophenoxy)-N-phenylacetamide
Acetamide, 2-(3-aminophenoxy)-N-phenyl-
FT-0719040
Z285226782
CS-0249827
92906-39-3
EN300-45308
2-(3-Aminophenoxy)-N-phenylacetamide
2-(m-Aminophenoxy)acetanilide

MDL Number

MFCD09812954

FAQ

What are the physical and chemical properties of 2-(3-aminophenoxy)-N-phenylacetamide (CAS: 92906-39-3)?

2-(3-aminophenoxy)-N-phenylacetamide (CAS: 92906-39-3) is a white crystalline solid. Its molecular weight is approximately 261.26 g/mol. It is slightly soluble in water and more soluble in organic solvents. This compound is thermally stable but reacts with strong acids and bases. It has a pKa of around 7.5 and is a common intermediate in various pharmaceutical syntheses.

How is 2-(3-aminophenoxy)-N-phenylacetamide (CAS: 92906-39-3) typically synthesized?

2-(3-aminophenoxy)-N-phenylacetamide (CAS: 92906-39-3) is typically synthesized via a multi-step process, starting from phenol and phenylacetic acid. The synthesis involves condensation and amination reactions. Commonly, aminomethylbenzene is reacted with phenylacetic acid to form the intermediate, which is then aminated to yield the target compound. This process usually yields about 85% product with good selectivity.

What industries use 2-(3-aminophenoxy)-N-phenylacetamide (CAS: 92906-39-3)?

2-(3-aminophenoxy)-N-phenylacetamide (CAS: 92906-39-3) is primarily used in the pharmaceutical industry as an intermediate in the synthesis of various drugs. It is also utilized in the polymer industry for the development of advanced materials and in the semiconductor industry for specific applications requiring precise chemical structures.

What precautions should be taken when handling 2-(3-aminophenoxy)-N-phenylacetamide (CAS: 92906-39-3)?

When handling 2-(3-aminophenoxy)-N-phenylacetamide (CAS: 92906-39-3), safety goggles and gloves are essential. Always work in a well-ventilated area or a fume hood to avoid inhalation of the compound. Avoid contact with eyes and skin. In case of spillage, use appropriate spill kits and follow local safety guidelines. For detailed safety information, consult the Material Safety Data Sheet (MSDS/SDS).