L-Valylglycyl-L-valyl-L-alanyl-L-prolylglycine | CAS No. 92899-39-3

L-Valylglycyl-L-valyl-L-alanyl-L-prolylglycine

Basic Information

CAS Number

92899-39-3

Molecular Formula

C22H38N6O7

Molecular Weight

498.58 g/mol

AD

Basic Physical Properties

CC(C)C(C(=O)NCC(=O)NC(C(C)C)C(=O)NC(C)C(=O)N1CCCC1C(=O)NCC(=O)O)N

InChI

InChI=1S/C22H38N6O7/c1-11(2)17(23)20(33)24-9-15(29)27-18(12(3)4)21(34)26-13(5)22(35)28-8-6-7-14(28)19(32)25-10-16(30)31/h11-14,17-18H,6-10,23H2,1-5H3,(H,24,33)(H,25,32)(H,26,34)(H,27,29)(H,30,31)/t13-,14-,17-,18-/m0/s1

InChIKey

RLCSROTYKMPBDL-USJZOSNVSA-N

LogP

-2.0767999999999924

Topological Polar Surface Area

200.03 Ų

Hydrogen Bond Donor/Acceptor

7 / 13

Complexity

816

Synonyms & References

English

  • Chemotactic Domain of Elastin
  • N-[(1-{N-[2-({2-[(2-Amino-1-hydroxy-3-methylbutylidene)amino]-1-hydroxyethylidene}amino)-1-hydroxy-3-methylbutylidene]alanyl}pyrrolidin-2-yl)(hydroxy)methylidene]glycine
  • Glycine, N-(1-(N-(N-(N-L-valylglycyl)-L-valyl)-L-alanyl)-L-prolyl)-, (SP-4-2)-
  • SCHEMBL1404295
  • HEXAPEPTIDE-12 (VAL-GLY-VAL-ALA-PRO-GLY) [INCI]
  • Val-Gly-Val-Ala-Pro-Gly
  • hexapeptide-12 (val-gly-val-ala-pro-gly)
  • 92899-39-3
  • 04V1QPJ5TW
  • Val-gly-ala-pro-gly
  • H-Val-Gly-Val-Ala-Pro-Gly-OH
  • CS-0675630
  • DTXSID50918909
  • Valyl-glycyl-valyl-alanyl-prolyl-glycine
  • 2-[[(2S)-1-[(2S)-2-[[(2S)-2-[[2-[[(2S)-2-amino-3-methylbutanoyl]amino]acetyl]amino]-3-methylbutanoyl]amino]propanoyl]pyrrolidine-2-carbonyl]amino]acetic acid
  • DERMAXYL
  • UNII-04V1QPJ5TW
  • L-Glycine High7408
  • HY-P4998
  • MFCD00133914
  • L-Glycine High
  • 2-((S)-1-((S)-2-((S)-2-(2-((S)-2-Amino-3-methylbutanamido)acetamido)-3-methylbutanamido)Propanoyl)pyrrolidine-2-carboxamido)acetic acid
  • Chemotactic Domain of Elastin (H-L-Val-Gly-L-Val-L-Ala-L-Pro-Gly-OH)
  • Vgvapg
  • L-Glycine7407
  • Q27247699
  • Glycine, L-valylglycyl-L-valyl-L-alanyl-L-prolyl-
  • Glycine,L-valylglycyl-L-valyl-L-alanyl-L-prolyl-
  • CHEMOTACTIC DOMAIN OF ELASTIN
  • ChemostaticdomainofElastin
  • H-VAL-GLY-VAL-ALA-PRO-GLY-OH

MDL Number

MFCD00133914

FAQ

What are the physical and chemical properties of L-Valylglycyl-L-valyl-L-alanyl-L-prolylglycine (CAS: 92899-39-3)?

L-Valylglycyl-L-valyl-L-alanyl-L-prolylglycine is a crystalline compound with a molecular weight of approximately 555.59 g/mol. It is poorly soluble in water but soluble in organic solvents. Chemically, it is relatively stable but can undergo hydrolysis under acidic or basic conditions. It has a pKa of around 7, indicating a neutral to slightly basic nature.

How is L-Valylglycyl-L-valyl-L-alanyl-L-prolylglycine (CAS: 92899-39-3) typically synthesized?

L-Valylglycyl-L-valyl-L-alanyl-L-prolylglycine is synthesized through a multistep peptide synthesis process, utilizing solid-phase peptide synthesis (SPPS) techniques. Commonly, a protected form of each amino acid is used, and the peptide is constructed stepwise. Key reagents include coupling agents like HATU and scavengers such as HOAc. The final product is deprotected and purified via HPLC.

What industries use L-Valylglycyl-L-valyl-L-alanyl-L-prolylglycine (CAS: 92899-39-3)?

L-Valylglycyl-L-valyl-L-alanyl-L-prolylglycine is primarily used in the pharmaceutical industry due to its biological activity. It is also explored in the development of certain polymers for biomedical applications, as well as in the production of sensors and semiconductors for their unique chemical structure and reactivity.

What precautions should be taken when handling L-Valylglycyl-L-valyl-L-alanyl-L-prolylglycine (CAS: 92899-39-3)?

When handling L-Valylglycyl-L-valyl-L-alanyl-L-prolylglycine, it is essential to wear proper personal protective equipment (PPE), including gloves, goggles, and a lab coat. Work should be conducted in a well-ventilated area or fume hood. Spills should be cleaned up using appropriate reagents, and proper disposal methods should be followed. Always refer to the Safety Data Sheet (SDS) for detailed safety information.

You might also like

Compound Q&A

What is 6-Methyl-7-oxabicyclo[4.1.0]heptan-2-one (CAS: 21889-89-4)?

6-Methyl-7-oxabicyclo[4.1.0]heptan-2-one is a cyclic ketone with a molecular for...

21889-89-46-Methyl-7-oxabicycl...
Compound Q&A

What is 4-[(6-Methyl-2-pyrazinyl)oxy]benzoic acid (CAS: 906353-00-2)?

4-[(6-Methyl-2-pyrazinyl)oxy]benzoic acid is a chemical compound with the CAS nu...

906353-00-24-[(6-Methyl-2-pyraz...
Compound Q&A

What is 2-(2-Pyridinyl)-1,3-propanediol (CAS: 49745-42-8)?

2-(2-Pyridinyl)-1,3-propanediol (CAS: 49745-42-8) is a colorless to slightly yel...

49745-42-82-(2-Pyridinyl)-1,3-...
Compound Q&A

What is 2-(6-Chloro-2-pyridinyl)-2-phenylacetonitrile (CAS: 24783-42-4)?

2-(6-Chloro-2-pyridinyl)-2-phenylacetonitrile is an organic compound with the CA...

24783-42-42-(6-Chloro-2-pyridi...
Compound Q&A

What is 2-Oxopropanamide (CAS: 631-66-3)?

2-Oxopropanamide, also known as 2-aminoacrylic acid, is a chemical compound with...

631-66-32-Oxopropanamide
Compound Q&A

What is 2-Methyl-2-propanyl 4-(5-bromo-6-methyl-2-pyridinyl)-1-piperazinecarboxylate (CAS: 1289040-88-5)?

2-Methyl-2-propanyl 4-(5-bromo-6-methyl-2-pyridinyl)-1-piperazinecarboxylate (CA...

1289040-88-52-Methyl-2-propanyl ...
Compound Q&A

What is NAMPT inhibitor-linker 1 (CAS: 2241019-57-6)?

NAMPT inhibitor-linker 1 (CAS: 2241019-57-6) is a chemical compound designed as ...

2241019-57-6NAMPT inhibitor-link...
Compound Q&A

What is (2-(2,2,2-Trifluoroacetyl)pyridin-4-yl)boronic acid (CAS: 1310404-58-0)?

It is a chemical compound with the structure (2-(2,2,2-Trifluoroacetyl)pyridin-4...

1310404-58-0(2-(2,2,2-Trifluoroa...
Compound Q&A

What is 1-(2-Chlorophenyl)-6-(3,3,3-trifluoro-2-methylpropyl)-1,5-dihydro-4H-pyrazolo[3,4-d]pyrimidin-4-one (CAS: 794568-90-4)?

1-(2-Chlorophenyl)-6-(3,3,3-trifluoro-2-methylpropyl)-1,5-dihydro-4H-pyrazolo[3,...

794568-90-41-(2-Chlorophenyl)-6...
Compound Q&A

What is Vinyl(chloromethyl)dimethoxysilane (CAS: 1314981-48-0)?

Vinyl(chloromethyl)dimethoxysilane is an organosilicon compound with the molecul...

1314981-48-0Vinyl(chloromethyl)d...