Butyl (2R)-2-hydroxybutanoate

Basic Information

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CAS Number

928835-95-4

Molecular Formula

C8H16O3

Molecular Weight

160.21 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Esters

Basic Chemical Raw Materials Organic Chemicals Ethers

Basic Physical Properties

SMILES

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O(C([C@@H](CC)O)=O)CCCC

InChI

1S/C8H16O3/c1-3-5-6-11-8(10)7(9)4-2/h7,9H,3-6H2,1-2H3/t7-/m1/s1

InChIKey

YFFBWGUXPFAXRS-SSDOTTSWSA-N

LogP

1.1006

Topological Polar Surface Area

46.53 Å²

Hydrogen Bond Donor/Acceptor

1 / 3

Complexity

112

Synonyms & References

English

Butanoic acid,2-hydroxy-,butyl ester,(2r)-
butyl (2R)-2-hydroxybutanoate
[R,(+)]-2-Hydroxybutyric acid butyl ester
Butanoic acid, 2-hydroxy-, butyl ester, (2R)-

FAQ

What are the physical and chemical properties of Butyl (2R)-2-hydroxybutanoate (CAS: 928835-95-4)?

Butyl (2R)-2-hydroxybutanoate (CAS: 928835-95-4) is a colorless to white crystalline solid with a molecular weight of approximately 168.21 g/mol. It has a solubility of up to 1 g/100 mL in water and is practically insoluble in hexane. This compound exhibits moderate reactivity, particularly in esterification and hydrolysis reactions.

How is Butyl (2R)-2-hydroxybutanoate (CAS: 928835-95-4) typically synthesized?

Butyl (2R)-2-hydroxybutanoate is typically synthesized via the esterification of 2-hydroxybutanoic acid with butanol in the presence of a catalytic amount of acetic anhydride. The reaction is carried out under mild conditions with good selectivity and yields of up to 95%. The process is commonly performed using a Dean-Stark apparatus to remove water formed during the reaction.

What industries use Butyl (2R)-2-hydroxybutanoate (CAS: 928835-95-4)?

Butyl (2R)-2-hydroxybutanoate (CAS: 928835-95-4) is primarily used in the pharmaceutical industry as a raw material for drug synthesis. It also finds applications in polymer industry for producing biodegradable plastics and in the sensor industry for developing chemical sensors. Additionally, it is used in the semiconductor industry as a cleaning agent.

What precautions should be taken when handling Butyl (2R)-2-hydroxybutanoate (CAS: 928835-95-4)?

When handling Butyl (2R)-2-hydroxybutanoate (CAS: 928835-95-4), it is important to wear appropriate personal protective equipment (PPE) such as gloves, safety goggles, and a lab coat. This compound should be used in a well-ventilated environment or under a fume hood to minimize inhalation risks. In case of a spill, immediately clean up the area using appropriate absorbents and dispose of according to local regulations. Refer to the Safety Data Sheet (SDS) for detailed handling and disposal information.