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Methyl (Z)-3-[[[4-[N-methyl-2-(4-methylpiperazin-1-yl)acetamido]phenyl]amino](phenyl)methylene]-2-oxoindoline-6-carboxylate | CAS No. 928326-83-4

Methyl (Z)-3-[[[4-[N-methyl-2-(4-methylpiperazin-1-yl)acetamido]phenyl]amino](phenyl)methylene]-2-oxoindoline-6-carboxylate

Basic Information

Chemical_Structure_Of
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CAS Number

928326-83-4

Molecular Formula

C31H33N5O4

Molecular Weight

539.6 g/mol

AD

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids
Basic Chemical Raw Materials Organic Chemicals Esters
Basic Chemical Raw Materials Organic Chemicals Ethers
Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds
Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates
Fine Chemicals Dyes and Pigments Organic Dyes
Fine Chemicals Surfactants Anionic Surfactants
Laboratory Chemicals Research Chemicals Biochemical Reagents

Basic Physical Properties

SMILES

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CN1CCN(CC1)CC(=O)N(C)C2=CC=C(C=C2)N=C(C3=CC=CC=C3)C4=C(NC5=C4C=CC(=C5)C(=O)OC)O

InChI

InChI=1S/C31H33N5O4/c1-34-15-17-36(18-16-34)20-27(37)35(2)24-12-10-23(11-13-24)32-29(21-7-5-4-6-8-21)28-25-14-9-22(31(39)40-3)19-26(25)33-30(28)38/h4-14,19,33,38H,15-18,20H2,1-3H3

InChIKey

CPMDPSXJELVGJG-UHFFFAOYSA-N

LogP

4.039400000000003

Topological Polar Surface Area

101.47 Ų

Hydrogen Bond Donor/Acceptor

2 / 9

Complexity

892

Synonyms & References

English

  • 656247-17-5
  • BRD-K49075727-001-01-0
  • BIBF 1120
  • OFEV COMPONENT NINTEDANIB
  • CCG-264775
  • 1H-Indole-6-carboxylic acid, 2,3-dihydro-3-[[[4-[methyl[2-(4-methyl-1-piperazinyl)acetyl]amino]phenyl]amino]phenylmethylene]-2-oxo-, methyl ester
  • BIBF1120
  • FT-0772497
  • NSC-757442
  • NCGC00263156-02
  • US10669235, Nintedanib
  • NSC-756659
  • Methyl (3Z)-3-(((4-(N-methyl-2-(4-methylpiperazin-1-yl)acetamido)phenyl)amino)(phenyl)methylidene)-2-oxo-2,3-dihydro-1h-indole-6-carboxylate
  • Vargatef Base
  • GTPL5936
  • EX-A2818
  • NSC-800805
  • G6HRD2P839
  • Nintedanib [INN]
  • CHEBI:91413
  • SMR004701273
  • XZXHXSATPCNXJR-ZIADKAODSA-N
  • D10481
  • 3-Z-[1-(4-(N-((4-methyl-piperazin-1-yl)-methylcarbonyl)-N-methyl-amino)-anilino)-1-phenyl-methylene]-6-methoxycarbonyl-2-indolinone
  • HMS3244B06
  • AC-25071
  • s1010
  • BDBM445209
  • CHEBI:85164
  • HMS3295K01
  • SB11190

MDL Number

MFCD11974012

FAQ

What regulatory guidelines apply to Methyl (Z)-3-[[[4-[N-methyl-2-(4-methylpiperazin-1-yl)acetamido]phenyl]amino](phenyl)methylene]-2-oxoindoline-6-carboxylate (CAS: 928326-83-4)?
Methyl (Z)-3-[[[4-[N-methyl-2-(4-methylpiperazin-1-yl)acetamido]phenyl]amino](phenyl)methylene]-2-oxoindoline-6-carboxylate (CAS: 928326-83-4) falls under the scope of the REACH regulation for chemicals in the European Union. It is also subject to the Globally Harmonized System (GHS) for classification and labeling of chemicals. In the United States, it must comply with FDA and EPA regulations for the import, production, and use of pharmaceutical intermediates and environmental chemicals.

Are there alternatives to Methyl (Z)-3-[[[4-[N-methyl-2-(4-methylpiperazin-1-yl)acetamido]phenyl]amino](phenyl)methylene]-2-oxoindoline-6-carboxylate (CAS: 928326-83-4) in synthesis?
Alternatives to Methyl (Z)-3-[[[4-[N-methyl-2-(4-methylpiperazin-1-yl)acetamido]phenyl]amino](phenyl)methylene]-2-oxoindoline-6-carboxylate (CAS: 928326-83-4) in synthesis include other derivatives of indoline, such as methyl (Z)-3-[[[4-(2-aminoethyl)phenyl]amino](phenyl)methylene]-2-oxoindoline-6-carboxylate and methyl (Z)-3-[[[4-(2-morpholinoethyl)phenyl]amino](phenyl)methylene]-2-oxoindoline-6-carboxylate. Common alternative reagents include various amines, carboxylic acids, and amino acids.

What is the market or research trend for Methyl (Z)-3-[[[4-[N-methyl-2-(4-methylpiperazin-1-yl)acetamido]phenyl]amino](phenyl)methylene]-2-oxoindoline-6-carboxylate (CAS: 928326-83-4)?
Methyl (Z)-3-[[[4-[N-methyl-2-(4-methylpiperazin-1-yl)acetamido]phenyl]amino](phenyl)methylene]-2-oxoindoline-6-carboxylate (CAS: 928326-83-4) is a research chemical with potential applications in pharmaceuticals and materials science. Market trends include increased interest in drug discovery and development, with ongoing research focusing on its biological activity and applicability in medicinal chemistry. There is also a growing trend towards sustainable and green chemistry methods in its synthesis.

How should waste containing Methyl (Z)-3-[[[4-[N-methyl-2-(4-methylpiperazin-1-yl)acetamido]phenyl]amino](phenyl)methylene]-2-oxoindoline-6-carboxylate (CAS: 928326-83-4) be handled?
Waste containing Methyl (Z)-3-[[[4-[N-methyl-2-(4-methylpiperazin-1-yl)acetamido]phenyl]amino](phenyl)methylene]-2-oxoindoline-6-carboxylate (CAS: 928326-83-4) should be collected in appropriate containers and handled according to local regulations. Incineration is a common method for disposal, but professional waste disposal services are recommended due to its chemical properties. Proper environmental protection measures, such as containment and neutralization of acidic or basic waste, should be followed to minimize environmental impact.

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JiNaXuanDe Chemical Co Ltd

CAS Number: 928326-83-4

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Methyl (Z)-3-[[[4-[N-methyl-2-(4-methylpiperazin-1-yl)acetamido]phenyl]amino](phenyl)methylene]-2-oxoindoline-6-carboxylate — HuBeiMoDe Chemical Co Ltd

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Methyl (Z)-3-[[[4-[N-methyl-2-(4-methylpiperazin-1-yl)acetamido]phenyl]amino](phenyl)methylene]-2-oxoindoline-6-carboxylate — Hubei Chenghai Chemical Co., Ltd.

Hubei Chenghai Chemical Co., Ltd.

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Methyl (Z)-3-[[[4-[N-methyl-2-(4-methylpiperazin-1-yl)acetamido]phenyl]amino](phenyl)methylene]-2-oxoindoline-6-carboxylate — HePeng （ ShangHai ） Biotechnology Co Ltd

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Methyl (Z)-3-[[[4-[N-methyl-2-(4-methylpiperazin-1-yl)acetamido]phenyl]amino](phenyl)methylene]-2-oxoindoline-6-carboxylate — TianMenHengChang Chemical Co Ltd

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Methyl (Z)-3-[[[4-[N-methyl-2-(4-methylpiperazin-1-yl)acetamido]phenyl]amino](phenyl)methylene]-2-oxoindoline-6-carboxylate — SaiDaoTongShengWuKeJi （ ShangHai ） YouXianGongSi - AnZhouBanShiChu

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