Ethyl (2-{[(benzyloxy)carbonyl]amino}-1,3-thiazol-4-yl)acetate | CAS No. 92592-02-4

Ethyl (2-{[(benzyloxy)carbonyl]amino}-1,3-thiazol-4-yl)acetate

Basic Information

CAS Number

92592-02-4

Molecular Formula

C15H16N2O4S

Molecular Weight

320.37 g/mol

AD

Basic Physical Properties

Density

1.326±0.06 g/cm3 (20 ºC 760 Torr),

CCOC(=O)CC1=CSC(=N1)NC(=O)OCC2=CC=CC=C2

InChI

InChI=1S/C15H16N2O4S/c1-2-20-13(18)8-12-10-22-14(16-12)17-15(19)21-9-11-6-4-3-5-7-11/h3-7,10H,2,8-9H2,1H3,(H,16,17,19)

InChIKey

PBZLVBQMTYWJAE-UHFFFAOYSA-N

LogP

2.9974000000000016

Topological Polar Surface Area

77.52 Ų

Hydrogen Bond Donor/Acceptor

1 / 6

Complexity

375

Synonyms & References

English

  • Ethyl 2-(2-(((benzyloxy)carbonyl)amino)thiazol-4-yl)acetate
  • Ethyl (2-{[(benzyloxy)carbonyl]amino}-1,3-thiazol-4-yl)acetate
  • 92592-02-4
  • DTXSID30635960
  • ETHYL 2-(2-{[(BENZYLOXY)CARBONYL]AMINO}-1,3-THIAZOL-4-YL)ACETATE
  • Oprea1_842010
  • ethyl 2-[2-(phenylmethoxycarbonylamino)-1,3-thiazol-4-yl]acetate
  • Ethyl 2-(2-benzyloxycarbonylaminothiazol-4-yl) acetate
  • Ethyl2-(2-(((benzyloxy)carbonyl)amino)thiazol-4-yl)acetate
  • AKOS009132661
  • ethyl 2-[2-(phenylmethoxycarbonylamino)-1,3-thiazol-4-yl]ethanoate
  • SB83254
  • 2-[2-(phenylmethoxycarbonylamino)-4-thiazolyl]acetic acid ethyl ester
  • FT-0656232
  • A844283
  • Ethyl 2-(2-benzyloxycarbonylaminothiazol-4-yl)acetate

MDL Number

MFCD02325260

FAQ

What are the physical and chemical properties of Ethyl (2-{[(benzyloxy)carbonyl]amino}-1,3-thiazol-4-yl)acetate (CAS: 92592-02-4)?

Ethyl (2-{[(benzyloxy)carbonyl]amino}-1,3-thiazol-4-yl)acetate is a white crystalline solid with a molecular weight of approximately 368.39 g/mol. It is slightly soluble in water and has good solubility in organic solvents. This compound is known for its reactivity, particularly towards nucleophiles and bases, making it suitable for various chemical reactions.

How is Ethyl (2-{[(benzyloxy)carbonyl]amino}-1,3-thiazol-4-yl)acetate (CAS: 92592-02-4) typically synthesized?

Ethyl (2-{[(benzyloxy)carbonyl]amino}-1,3-thiazol-4-yl)acetate is typically synthesized through a multi-step process involving the coupling of an appropriate thiazole derivative with an amine and an acylating agent. The synthesis often involves the use of a catalyst and requires careful control of reaction conditions to achieve high selectivity and yield.

What industries use Ethyl (2-{[(benzyloxy)carbonyl]amino}-1,3-thiazol-4-yl)acetate (CAS: 92592-02-4)?

Ethyl (2-{[(benzyloxy)carbonyl]amino}-1,3-thiazol-4-yl)acetate finds applications in the pharmaceutical industry due to its potential as a precursor for drug intermediates. It is also used in the synthesis of polymers, where its thiazole moiety can contribute to the properties of the final material. Additionally, this compound is utilized in the development of sensors and semiconductors for its unique reactivity and functional groups.

What precautions should be taken when handling Ethyl (2-{[(benzyloxy)carbonyl]amino}-1,3-thiazol-4-yl)acetate (CAS: 92592-02-4)?

When handling Ethyl (2-{[(benzyloxy)carbonyl]amino}-1,3-thiazol-4-yl)acetate (CAS: 92592-02-4), it is crucial to wear appropriate personal protective equipment (PPE), including gloves, goggles, and a lab coat. Work should be conducted in a well-ventilated area or a fume hood to minimize the risk of exposure. In case of a spill, immediately clean up using appropriate tools and materials, and ensure proper disposal following safety guidelines. Always refer to the safety data sheet (SDS) for detailed handling and emergency procedures.

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