N-Nitrosodibutylamine | CAS No. 924-16-3

Q: What are the physical and chemical properties of N-Nitrosodibutylamine (CAS: 924-16-3)?

N-Nitrosodibutylamine (CAS: 924-16-3) is a colorless or pale yellow liquid with a molecular weight of approximately 178.15 g/mol. It has a low boiling point of 138°C and is slightly soluble in water but soluble in organic solvents like ethanol and acetone. It is a potent carcinogen and should be handled with caution due to its reactivity and potential for forming nitrosamines.

Q: How is N-Nitrosodibutylamine (CAS: 924-16-3) typically synthesized?

N-Nitrosodibutylamine is typically synthesized through the reaction of dinitriloethylene and dibutylamine. The process involves the nitrosation of ethylenediamine followed by the reaction with dibutylamine under controlled conditions. This synthesis often requires careful temperature and pH control to achieve the desired yield and selectivity.

Q: What industries use N-Nitrosodibutylamine (CAS: 924-16-3)?

N-Nitrosodibutylamine (CAS: 924-16-3) has limited industrial applications due to its high toxicity. It is primarily used in research as a carcinogen and in the development of other compounds. Its usage is strictly regulated and typically confined to academic and pharmaceutical research contexts.

Q: What precautions should be taken when handling N-Nitrosodibutylamine (CAS: 924-16-3)?

When handling N-Nitrosodibutylamine (CAS: 924-16-3), it is crucial to wear appropriate personal protective equipment (PPE) including gloves, goggles, and a lab coat. Work should be conducted in a fume hood to minimize exposure. Spills should be cleaned up with care, using appropriate absorbents, and disposing of contaminated materials according to local regulations. Always refer to the Safety Data Sheet (SDS) for detailed handling instructions and emergency procedures.

N-Nitrosodibutylamine

Basic Information

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CAS Number

924-16-3

Molecular Formula

C8H18N2O

Molecular Weight

158.24 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Physical Properties

Melting Point

<25 ºC

Boiling Point

237°C

Density

0.9 g/mL

Flash Point

105.3±18.7 ºC,

Refractive Index

1.4485 (589.3 nm 20 ºC)

SMILES

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CCCCN(CCCC)N=O

InChI

InChI=1S/C8H18N2O/c1-3-5-7-10(9-11)8-6-4-2/h3-8H2,1-2H3

InChIKey

YGJHZCLPZAZIHH-UHFFFAOYSA-N

LogP

2.570000000000001

Topological Polar Surface Area

32.67 Å²

Hydrogen Bond Donor/Acceptor

0 / 3

Complexity

88.1

Safety Information

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Hazard Statement

H302 Harmful if swallowed
Acute toxicity, oral

H351 Suspected of causing cancer
Carcinogenicity

Hazard Class

Class 6.1(b) Class 6.1(b)

Synonyms & References

English

1-Butanamine,N-butyl-N-nitroso-
N-Nitrosodibutylamine
Additional VOC’s by Method 8260B
Method 8270B - Nitrosamines Mix
N,N-dibutylnitrous amide
N-NITROSO-DI-N- BUTYLAMINE
N-Nitroso-di-n-butyl
N-Nitrosodi-n-butylamine
N-Nitrosodi-n-butylamine solution
7-Nitro-1H-indazole
N-Dibutylnitrosamine
NDBA
NSC 6830
Nitrosodibutylamine
Dibutylamine, N-nitroso- (6CI, 7CI, 8CI)
N-Butyl-N-nitroso-1-butanamine (ACI)
Di-n-butylnitrosamine
Dibutylnitrosamine
N,N-Di-n-butylnitrosamine
N,N-Dibutylnitrosamine
N,N-Dibutylnitrous amide
N-Nitroso-N-di-n-butylamine
N-Nitroso-di-n-butylamine
N,NDibutylnitrosoamine
NCGC00248027-01
NCGC00259883-01
NCGC00254330-01
N0375
CHEBI:82356
NButylNnitroso1butaneamine
D91692

MDL Number

MFCD00013892

Customs Code

2928000090

FAQ

What are the physical and chemical properties of N-Nitrosodibutylamine (CAS: 924-16-3)?

N-Nitrosodibutylamine (CAS: 924-16-3) is a colorless or pale yellow liquid with a molecular weight of approximately 178.15 g/mol. It has a low boiling point of 138°C and is slightly soluble in water but soluble in organic solvents like ethanol and acetone. It is a potent carcinogen and should be handled with caution due to its reactivity and potential for forming nitrosamines.

How is N-Nitrosodibutylamine (CAS: 924-16-3) typically synthesized?

N-Nitrosodibutylamine is typically synthesized through the reaction of dinitriloethylene and dibutylamine. The process involves the nitrosation of ethylenediamine followed by the reaction with dibutylamine under controlled conditions. This synthesis often requires careful temperature and pH control to achieve the desired yield and selectivity.

What industries use N-Nitrosodibutylamine (CAS: 924-16-3)?

N-Nitrosodibutylamine (CAS: 924-16-3) has limited industrial applications due to its high toxicity. It is primarily used in research as a carcinogen and in the development of other compounds. Its usage is strictly regulated and typically confined to academic and pharmaceutical research contexts.

What precautions should be taken when handling N-Nitrosodibutylamine (CAS: 924-16-3)?

When handling N-Nitrosodibutylamine (CAS: 924-16-3), it is crucial to wear appropriate personal protective equipment (PPE) including gloves, goggles, and a lab coat. Work should be conducted in a fume hood to minimize exposure. Spills should be cleaned up with care, using appropriate absorbents, and disposing of contaminated materials according to local regulations. Always refer to the Safety Data Sheet (SDS) for detailed handling instructions and emergency procedures.