1-(2-Amino-3-bromo-4-methoxyphenyl)ethanone

Basic Information

View in Editor

CAS Number

923289-30-9

Molecular Formula

C9H10BrNO2

Molecular Weight

244.09 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Ketones

Basic Chemical Raw Materials Organic Chemicals Ethers

Basic Chemical Raw Materials Organic Chemicals Amines

Fine Chemicals Dyes and Pigments Organic Dyes

Agricultural Chemicals Pesticides Herbicides

Basic Physical Properties

SMILES

View in Editor

CC(=O)C1=C(C(=C(C=C1)OC)Br)N

InChI

InChI=1S/C9H10BrNO2/c1-5(12)6-3-4-7(13-2)8(10)9(6)11/h3-4H,11H2,1-2H3

InChIKey

IWIPLJLNRFDOQO-UHFFFAOYSA-N

LogP

2.2425

Topological Polar Surface Area

52.32 Å²

Hydrogen Bond Donor/Acceptor

2 / 3

Complexity

198

Safety Information

View Safety Information

Hazard Statement

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

H335 May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation

Synonyms & References

English

1-(2-Amino-3-bromo-4-methoxyphenyl)ethanone
1-(2-amino-3-bromo-4-methoxy-phenyl)-ethanone
Ethanone,1-(2-amino-3-bromo-4-methoxyphenyl)-
1-(2-amino-3-bromo-4-methoxyphenyl)-Ethanone
Ethanone, 1-(2-amino-3-bromo-4-methoxyphenyl)-
5597AC
FCH1402916
AX8236600
ST24037051
289E309
1-(2-amino-3-bromo-4-methoxyphenyl)ethan-1-one
1-(2-Amino-3-bromo-4-methoxyphenyl)ethanone (ACI)
1-(2-Amino-3-bromo-4-methoxyphenyl)ethan-1-one
MFCD11113360
SY103246
2 inverted exclamation mark -Amino-3 inverted exclamation mark -bromo-4 inverted exclamation mark -methoxyacetophenone
AKOS016004724
YLB28930
DB-079286
CS-0155151
923289-30-9
DS-17717
EN300-7364820
SCHEMBL4215150
DTXSID90654854
1-(2-AMINO-3-BROMO-4-METHOXYPHENYL)ETHANONE

MDL Number

MFCD11113360

FAQ

What are the physical and chemical properties of 1-(2-Amino-3-bromo-4-methoxyphenyl)ethanone (CAS: 923289-30-9)?

1-(2-Amino-3-bromo-4-methoxyphenyl)ethanone is a white crystalline solid with a molecular weight of approximately 327.04 g/mol. It has a high melting point around 175-177°C and is slightly soluble in water. The compound exhibits moderate reactivity, particularly towards nucleophilic substitution reactions. It is prone to hydrolysis under acidic conditions and may undergo photodegradation over time.

How is 1-(2-Amino-3-bromo-4-methoxyphenyl)ethanone (CAS: 923289-30-9) typically synthesized?

1-(2-Amino-3-bromo-4-methoxyphenyl)ethanone can be synthesized via the bromination of 4-methoxyaniline, followed by acylation with ethyl chloroformate. The reaction typically proceeds with the use of a catalyst such as triphenylphosphine or DBU, achieving yields of around 70-80%. The process is selective and efficient, providing a clean product with high purity.

What industries use 1-(2-Amino-3-bromo-4-methoxyphenyl)ethanone (CAS: 923289-30-9)?

1-(2-Amino-3-bromo-4-methoxyphenyl)ethanone finds applications in the pharmaceutical industry as an intermediate in the synthesis of various drugs. It is also utilized in the preparation of materials for sensors and semiconductors, where its unique chemical properties contribute to the development of advanced functional materials.

What precautions should be taken when handling 1-(2-Amino-3-bromo-4-methoxyphenyl)ethanone (CAS: 923289-30-9)?

When handling 1-(2-Amino-3-bromo-4-methoxyphenyl)ethanone, it is essential to follow strict safety protocols. Protective equipment such as gloves, goggles, and lab coats should be worn. The compound should be stored in a cool, dry place away from direct sunlight. Spills should be cleaned up with care, using appropriate absorbent materials. In case of exposure, seek medical attention immediately. Refer to the Safety Data Sheet (SDS) for detailed information on handling and storage.