Azd-1656 | CAS No. 919783-22-5

Azd-1656

Basic Information

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CAS Number

919783-22-5

Molecular Formula

C24H26N6O5

Molecular Weight

478.51 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Ethers

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Dyes and Pigments Organic Dyes

Fine Chemicals Surfactants Anionic Surfactants

Laboratory Chemicals Research Chemicals Biochemical Reagents

Basic Physical Properties

Boiling Point

635.0±55.0 °C(Predicted)

Density

1.336±0.06 g/cm3(Predicted)

SMILES

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CC1=CN=C(C=N1)NC(=O)C2=CC(=CC(=C2)OC(C)COC)OC3=NC=C(N=C3)C(=O)N4CCC4

InChI

InChI=1S/C24H26N6O5/c1-15-10-27-21(12-25-15)29-23(31)17-7-18(34-16(2)14-33-3)9-19(8-17)35-22-13-26-20(11-28-22)24(32)30-5-4-6-30/h7-13,16H,4-6,14H2,1-3H3,(H,27,29,31)/t16-/m0/s1

InChIKey

FJEJHJINOKKDCW-INIZCTEOSA-N

LogP

2.879220000000001

pKa

10.84±0.70(Predicted)

Topological Polar Surface Area

128.66000000000003 Å²

Hydrogen Bond Donor/Acceptor

1 / 11

Complexity

710

Synonyms & References

English

AZD 1656
AZD1656
AZD-1656
3-[5-(azetidine-1-carbonyl)pyrazin-2-yl]oxy-5-[(2S)-1-methoxypropan-2-yl]oxy-N-(5-methylpyrazin-2-yl)benzamide
Benzamide, 3-[[5-(1-azetidinylcarbonyl)-2-pyrazinyl]oxy]-5-[(1S)-2-methoxy-1-methylethoxy]-N-(5-methyl-2-pyrazinyl)-
Hexokinase IV,Glucokinase,AZD-1656,AZD1656,G6pc,G6P,ChREBP-β,hypoglycemia,inhibit,Inhibitor,Hexokinase D,epinephrine,glucagon,antihyperglycemic
Benzamide,3-[[5-(1-azetidinylcarbonyl)-2-pyrazinyl]oxy]-5-[(1S)-2-methoxy-1-methylethoxy]-N-(5-methyl-2-pyrazinyl)-
FJEJHJINOKKDCW-INIZCTEOSA-N
3-{[5-(azetidin-1-ylcarbonyl)pyrazin-2-yl]oxy}-5-{[(1S)-1-methyl-2-(methyloxy)ethyl]oxy}-N-(5-methylpyrazin-2-yl)benzamide
GTPL7701
660M185X4D
DB14810
Q27074714
(S)-3-(5-(Azetidine-1-carbonyl)pyrazin-2-yloxy)-5-(1-methoxyprop
CID 16039797
3-[[5-(1-Azetidinylcarbonyl)-2-pyrazinyl]oxy]-5-[(1S)-2-methoxy-1-methylethoxy]-N-(5-methyl-2-pyrazinyl)benzamide (ACI)
MS-28891
3-(5-(azetidine-1-carbonyl)pyrazin-2-yl)oxy-5-((2S)-1-methoxypropan-2-yl)oxy-N-(5-methylpyrazin-2-yl)benzamide
(S)-3-(5-(Azetidine-1-carbonyl)pyrazin-2-yloxy)-5-(1-methoxypropan-2-yloxy)-N-(5-methylpyrazin-2-yl)benzamide
AZD 1656 [WHO-DD]
BA171838
CS-0008226
E77313
UNII-660M185X4D
HY-15675
CHEMBL3219124
GLXC-10480
DA-61373
919783-22-5
3-((5-(azetidine-1-carbonyl)pyrazin-2-yl)oxy)-5-(((2S)-1-methoxypropan-2-yl)oxy)-N-(5-methylpyrazin-2-yl)benzamide
3-((5-(AZETIDIN-1-YLCARBONYL)PYRAZIN-2-YL)OXY)-5-((1S)-2-METHOXY-1-METHYLETHOXY)-N-(5-METHYLPYRAZIN-2-YL)BENZAMIDE

MDL Number

MFCD28386282

FAQ

What is Azd-1656 (CAS: 919783-22-5)?

Azd-1656 is a chemical compound with the CAS number 919783-22-5. It is a potent and selective inhibitor of the VEGFR2 kinase, used in the development of targeted cancer therapies.

What are the main uses of Azd-1656 (CAS: 919783-22-5)?

Azd-1656 is primarily used in the pharmaceutical industry for the development of targeted cancer therapies. It is a key compound in clinical trials for the treatment of various types of cancer.

Is Azd-1656 (CAS: 919783-22-5) safe?

Azd-1656 is considered safe when used under professional supervision. However, it is important to follow all safety guidelines, including wearing appropriate personal protective equipment and handling in a well-ventilated area. Exposure to the compound should be minimized to ensure safety.

How should Azd-1656 (CAS: 919783-22-5) be stored?

Azd-1656 should be stored in a cool, dry place away from direct sunlight and heat sources. It should be kept in a tightly sealed container to prevent degradation. The storage temperature should be between 15°C and 25°C (59°F to 77°F).