Methyllithium

Basic Information

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CAS Number

917-54-4

Molecular Formula

CH3Li

Molecular Weight

21.98 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Hydrocarbons

Basic Physical Properties

Melting Point

70-71 ºC

Boiling Point

35℃

Density

0.846 g/mL at 25 °C

Water Solubility

Reacts with water.

Solubility

Reacts with water

Vapor Pressure

No data available

SMILES

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[Li+].[CH3-]

InChI

InChI=1S/CH3.Li/h1H3;

InChIKey

DVSDBMFJEQPWNO-UHFFFAOYSA-N

LogP

0.20299999999999996

Topological Polar Surface Area

0.0 Å²

Hydrogen Bond Donor/Acceptor

0 / 0

Complexity

Safety Information

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Hazard Statement

H224 Extremely flammable liquid and vapor
Flammable liquids

H250 Catches fire spontaneously if exposed to air
Pyrophoric liquids; Pyrophoric solids

H260 In contact with water releases flammable gases which may ignite spontaneously
Substances And Mixtures Which, In Contact With Water, Emit Flammable Gases

H302 Harmful if swallowed
Acute toxicity, oral

H305 May be fatal if swallowed and enters airways
Aspiration hazard

H314 Causes severe skin burns and eye damage
Skin corrosion/irritation

H361 Suspected of damaging fertility or the unborn child
Reproductive toxicity

Hazard Class

Class 4.3 Class 4.3

Sensitiveness

Air & Moisture Sensitive

Synonyms & References

English

Methyllithium
Methyllithium solution
Methyllithium lithium bromide complex solution
MethyllithiumcomplexedwithlithiumbromideinethyletherMc
lithium,carbanide
Methyllithium,1.0 M in 2-Methyltetrahydrofuran, SpcSeal
1.6 M in diethyl ether, MkSeal
Lithium methanide
Lithium methide
Lithium,methyl
MeLi
methyllitium
methyl-lithiu
Methyl-lithium
Lithium,methyl-
Methyllithium (ACI)
methyllithium
EINECS 213-026-4
MFCD00008253
CH3Li
Lithium, methyl-
IHLVCKWPAMTVTG-UHFFFAOYSA-N
M1655
AKOS015840105
NS00079585
methllithium
DTXSID7061273
methyllithum
917-54-4
CHEBI:51486
lithium;carbanide

MDL Number

MFCD00008253

FAQ

What regulatory guidelines apply to methyllithium (CAS: 917-54-4)?

Methyllithium (CAS: 917-54-4) is classified as a hazardous substance under the Globally Harmonized System of Classification and Labeling of Chemicals (GHS) due to its flammability and reactivity. It is regulated under the European Union's REACH (Registration, Evaluation, Authorisation and Restriction of Chemicals) and may also be subject to local and national regulations. Additionally, the U.S. FDA and EPA have specific requirements for the handling, storage, and disposal of methyllithium to ensure safety and environmental protection.

Are there alternatives to methyllithium (CAS: 917-54-4) in synthesis?

Several alternatives to methyllithium (CAS: 917-54-4) can be used in synthesis, including butyllithium, triethylaluminum, and sec-butyllithium. These reagents offer similar reactivity but with different handling requirements and safety profiles. The choice of alternative depends on the specific reaction conditions and the desired outcome of the synthesis.

What is the market or research trend for methyllithium (CAS: 917-54-4)?

The market for methyllithium (CAS: 917-54-4) has seen steady demand in organic synthesis and polymer chemistry. Recent research trends focus on developing safer and more efficient lithium reagents, as well as exploring new applications in materials science and pharmaceuticals. The price of methyllithium remains stable, though fluctuations in supply can affect market availability.

How should waste containing methyllithium (CAS: 917-54-4) be handled?

Waste containing methyllithium (CAS: 917-54-4) should be collected in a sealed, acid-resistant container and disposed of through a professional hazardous waste disposal service. It is crucial to ensure that any waste is properly neutralized to prevent reactions and to follow local and national regulations for the disposal of reactive and hazardous chemicals. Environmental protection measures should include the use of personal protective equipment and adherence to safety protocols during handling and disposal processes.