2-(Tert-butylamino)acetyl chloride hydrochloride

Basic Information

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CAS Number

915725-52-9

Molecular Formula

C6H13Cl2NO

Molecular Weight

186.08 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Physical Properties

SMILES

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CC(C)(C)NCC(=O)Cl.Cl

InChI

InChI=1S/C6H12ClNO.ClH/c1-6(2,3)8-4-5(7)9;/h8H,4H2,1-3H3;1H

InChIKey

DGVPZCIZHNTARH-UHFFFAOYSA-N

LogP

1.5617

Topological Polar Surface Area

29.1 Å²

Hydrogen Bond Donor/Acceptor

1 / 2

Complexity

106

Synonyms & References

English

2-[(tert-Butyl)amino]acetyl chloride hydrochloride
2-(tert-butyl)amino acetyl chloride hydrochloride
2-(tert-Butylamino)acetyl chloride hydrochloride
Acetyl chloride,2-[(1,1-dimethylethyl)amino]-,hydrochloride (1:1)
N-tert-Butylglycyl chloride hydrochloride
2-(tert-butylamino)acetyl chloride hydrochloride
2-(tert-butylamino)acetyl chloride,hydrochloride
n-t-butylglycine acid chloride hydrochloride
AC-23122
2-(tert-butylamino)acetylchloridehydrochloride
DGVPZCIZHNTARH-UHFFFAOYSA-N
N-tert-Butylglycyl chloride--hydrogen chloride (1/1)
915725-52-9
2-(tert-butylamino)acetyl chloride;hydrochloride
2-[(TERT-BUTYL)AMINO]ACETYL CHLORIDE HYDROCHLORIDE
MFCD02684430
2-(TERT-BUTYLAMINO)ACETYL CHLORIDE HCL
NS00078490
Acetyl chloride, 2-((1,1-dimethylethyl)amino)-, hydrochloride (1:1)
DS-9225
t-butylaminoacetyl chloride HCl
DTXSID10694757
SCHEMBL113153
EC 618-771-2
AKOS006276923

MDL Number

MFCD02684430

Customs Code

2942000000

FAQ

What are the physical and chemical properties of 2-(Tert-butylamino)acetyl chloride hydrochloride (CAS: 915725-52-9)?

2-(Tert-butylamino)acetyl chloride hydrochloride is a crystalline solid with a molecular weight of approximately 239.33 g/mol. It has a low solubility in water but is more soluble in organic solvents like dichloromethane and ethanol. Chemically, it is reactive, particularly towards nucleophiles, making it useful in organic synthesis. It can undergo hydrolysis in the presence of water, releasing acetic acid and tert-butylamine.

How is 2-(Tert-butylamino)acetyl chloride hydrochloride (CAS: 915725-52-9) typically synthesized?

2-(Tert-butylamino)acetyl chloride hydrochloride is typically synthesized by the reaction of tert-butylamine with acetyl chloride. The desired product forms in high yield, with careful control of reaction conditions to ensure selectivity. Commonly, this involves the use of catalytic quantities of an acid like sulfuric acid to promote the reaction. The product is then isolated by recrystallization from an appropriate solvent.

What industries use 2-(Tert-butylamino)acetyl chloride hydrochloride (CAS: 915725-52-9)?

2-(Tert-butylamino)acetyl chloride hydrochloride is used primarily in the pharmaceutical and polymer industries. In pharmaceuticals, it serves as a building block for the synthesis of various compounds with therapeutic potential. In polymers, it can act as a coupling agent, enhancing the adhesion between different polymer chains. Its reactivity and solubility make it suitable for specialized applications in materials science and electronics as well.

What precautions should be taken when handling 2-(Tert-butylamino)acetyl chloride hydrochloride (CAS: 915725-52-9)?

When handling 2-(Tert-butylamino)acetyl chloride hydrochloride, it is essential to use appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat. This compound should be used in a well-ventilated area or a fume hood due to its reactivity. Spills should be cleaned up carefully, and proper disposal procedures should be followed. Safety data sheets (SDS) should be consulted for detailed information on handling and emergency procedures.