Enzalutamide | CAS No. 915087-33-1

Enzalutamide

Basic Information

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CAS Number

915087-33-1

Molecular Formula

C21H16F4N4O2S

Molecular Weight

464.44 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Nitriles

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Dyes and Pigments Organic Dyes

Fine Chemicals Surfactants Anionic Surfactants

Fine Chemicals Specialty Chemicals UV Stabilizers

Agricultural Chemicals Pesticides Herbicides

Laboratory Chemicals Research Chemicals Biochemical Reagents

Basic Physical Properties

Density

1.49

SMILES

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CC1(C(=O)N(C(=S)N1C2=CC(=C(C=C2)C(=O)NC)F)C3=CC(=C(C=C3)C#N)C(F)(F)F)C

InChI

InChI=1S/C21H16F4N4O2S/c1-20(2)18(31)28(12-5-4-11(10-26)15(8-12)21(23,24)25)19(32)29(20)13-6-7-14(16(22)9-13)17(30)27-3/h4-9H,1-3H3,(H,27,30)

InChIKey

WXCXUHSOUPDCQV-UHFFFAOYSA-N

LogP

4.51338

Complexity

839

Safety Information

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GHS Hazard Pictograms

H302

Hazard Statement

H302 Harmful if swallowed
Acute toxicity, oral

Synonyms & References

English

Enzalutamide（MDV-3100）
[14C]-Enzalutamide
N-methyl-4-[3-(4-cyano-3-trifluoromethylphenyl)-5,5-dimethyl-4-oxo-2-thioxoimidazolidin-1-yl]-2-fluorobenzamide
4-(3-(4-cyano-3-(trifluoromethyl)phenyl)-5,5-dimethyl-4-oxo-2-thioxoimidazolidin-1-yl)-2-fluoro-N-methylbenzamide
Enzalutamide
MDV 3100
4-[3-[4-cyano-3-(trifluoromethyl)phenyl]-5,5-dimethyl-4-oxo-2-sulfanylideneimidazolidin-1-yl]-2-fluoro-N-methylbenzamide
Enzalutamide (MDV3100)
Enzalutamide(MDV3100,Xtandi®)
MDV-3100
UNII-93T0T9GKNU
XTANDI
4-[3-[4-Cyano-3-(trifluoromethyl)phenyl]-5,5-dimethyl-4-oxo-2-thioxo-1-imidazolidinyl]-2-fluoro-N-methylbenzamide (ACI)
S-Enzalutamide
Xtandi
AC-26924
SCHEMBL189749
NCGC00263120-01
L02BB04
NSC766085
ENZALUTAMIDE [INN]
D10218
MDV3100
DTXCID301341329
AS-17047
BDBM50425732
4-[3-[4-cyano-3-(trifluoromethyl)phenyl]-5,5-dimethyl-4-oxo-2-thioxo-imidazolidin-1-yl]-2-fluoro-N-methyl-benzamide
Enzalutamide (MDV3100)?
CS-0317
STL556766
ASP9785

MDL Number

MFCD14155804

Customs Code

2933990090

FAQ

What is Enzalutamide (CAS: 915087-33-1)?

Enzalutamide is a synthetic non-steroidal anti-androgen used primarily in the treatment of prostate cancer. Its chemical formula is C23H28N2O. It is a white to off-white solid with low solubility in water and is known for its ability to block androgen receptors, thereby inhibiting the growth of androgen-dependent cancer cells.

What are the main uses of Enzalutamide (CAS: 915087-33-1)?

Enzalutamide is mainly used in pharmaceuticals to treat advanced prostate cancer, particularly in patients who have developed resistance to other therapies like hormone therapy. It is also used in research for studying androgen receptor modulation and in drug development for related conditions.

Is Enzalutamide (CAS: 915087-33-1) safe?

Enzalutamide is considered safe when used as directed, but it requires careful handling due to potential toxicity. Precautions include avoiding exposure to skin and eyes, using appropriate personal protective equipment, and following safety guidelines to ensure proper disposal and minimize environmental impact.

How should Enzalutamide (CAS: 915087-33-1) be stored?

Enzalutamide should be stored in a cool, dry place away from light. It is typically kept in a sealed container at a temperature between 15°C to 25°C. Proper storage ensures stability and prevents degradation, maintaining its potency and safety for use.