Rubitecan | CAS No. 91421-42-0

Rubitecan

Basic Information

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CAS Number

91421-42-0

Molecular Formula

C20H15N3O6

Molecular Weight

393.35 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Esters

Basic Chemical Raw Materials Organic Chemicals Ethers

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Dyes and Pigments Organic Dyes

Fine Chemicals Surfactants Anionic Surfactants

Basic Physical Properties

Physical State

Powder

Melting Point

268°C

Boiling Point

816.3ºC at 760 mmHg

Density

1.63

Flash Point

106℃

Solubility

N/A

Refractive Index

1.761

Specific Rotation

+36.0° - +42.0° (c=0.4, CHCl3:MeOH=8:2)

SMILES

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CCC1(C2=C(COC1=O)C(=O)N3CC4=CC5=C(C=CC=C5[N+](=O)[O-])N=C4C3=C2)O

InChI

1S/C20H15N3O6/c1-2-20(26)13-7-16-17-10(8-22(16)18(24)12(13)9-29-19(20)25)6-11-14(21-17)4-3-5-15(11)23(27)28/h3-7,26H,2,8-9H2,1H3/t20-/m0/s1

InChIKey

VHXNKPBCCMUMSW-FQEVSTJZSA-N

LogP

2.51100

Complexity

861

Safety Information

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Hazard Statement

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

H335 May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation

Storage Conditions

2-8℃

Synonyms & References

English

9-NITROCAMPTOTHECIN
CAMPTOTHECIN, 9-NITRO-20(S)-(RG)
Rubitecan
1H-PYRANO[3',4':6,7]INDOLIZINO[1,2-B]QUINOLINE-3,14(4H,12H)-DIONE,4-ETHYL-4-HYDROXY-10-NITRO-, (4S)-
9-NITRO-20(S)-CAMPTOTHECIN
9-Nitrocellulose camptothecine
PYRIDOXINE 3,4-DIPALMITATE
(4S)-4-Ethyl-4-hydroxy-10-nitro-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14(4H,12H)-dione
Orathecin
9-Nitrocellulose camptothecine;Rubitecan
9-NC
Camptogen
RFS 2000
Nitrocamptothecin
H19C446XXB
C20H15N3O6
9NC
Rubitecan [USAN:INN]
rubitecanum
rubitecán
rubitécan
UQ0493300
(4s)-4-ethyl-4-hydroxy-10-nitro-1h-pyrano(3',4':6,7)indolizino(1,2-b)QUINOLINE-3,14(4h,12h)-dione
10-Nitro-camptothecin
9-nitro-(20S)-camptothecin
9-nitro-20-(S)-camptothecin
9-Nitrocamptothecin;Rubitecan
Camptogen; Orathecin
https://www.ebi.ac.uk/chebi/searchId.do?chebiId=CHEBI:90225
rubitecan; rubitecanum
Rubitecan|9-Nitrocamptothecin

MDL Number

MFCD06656294

FAQ

What is Rubitecan (CAS: 91421-42-0)?

Rubitecan, with the CAS number 91421-42-0, is a synthetic organic compound primarily used in pharmaceutical research. It is known for its antitumor properties and is often studied as a potential chemotherapy agent. The chemical formula of Rubitecan is C19H18N4O6, and it is characterized by its ability to inhibit DNA synthesis in cancer cells, making it a key focus in oncology studies.

What are the main uses of Rubitecan (CAS: 91421-42-0)?

Rubitecan (CAS: 91421-42-0) is mainly used in pharmaceutical research for its anticancer properties. It serves as a promising candidate in the development of new chemotherapy drugs. Additionally, it is explored for applications in medicinal chemistry and drug delivery systems due to its unique molecular structure and biological activity.

Is Rubitecan ( CAS: 91421-42-0 ) safe?

Rubitecan (CAS: 91421-42-0) is generally considered safe when handled properly in controlled environments. However, it may exhibit toxicity if misused or exposed in high concentrations. Safety measures include wearing protective gloves and goggles, and following standard laboratory protocols to minimize health risks. Its safety profile is under continuous evaluation for pharmaceutical applications.

How should Rubitecan (CAS: 91421-42-0) be stored?

Rubitecan (CAS: 91421-42-0) should be stored in a cool, dry, and dark place to maintain its stability. It is typically kept in a sealed container at a temperature below 25°C. Avoid exposure to moisture and direct light, as these can degrade the compound. Proper storage is essential to preserve its efficacy and safety for research and potential therapeutic use.