4-Morpholin-4-ylmethylbenzylamine

Basic Information

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CAS Number

91271-84-0

Molecular Formula

C12H18N2O

Molecular Weight

206.29 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Ethers

Basic Chemical Raw Materials Organic Chemicals Amines

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Basic Physical Properties

Melting Point

54-56°C

Boiling Point

324.7℃ at 760 mmHg

SMILES

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C1COCCN1CC2=CC=C(C=C2)CN

InChI

InChI=1S/C12H18N2O/c13-9-11-1-3-12(4-2-11)10-14-5-7-15-8-6-14/h1-4H,5-10,13H2

InChIKey

OTMQHFNPBREFIL-UHFFFAOYSA-N

LogP

0.9774999999999998

Topological Polar Surface Area

38.489999999999995 Å²

Hydrogen Bond Donor/Acceptor

2 / 3

Complexity

173

Safety Information

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Hazard Statement

H302 Harmful if swallowed
Acute toxicity, oral

H312 Harmful in contact with skin
Acute toxicity, dermal

H332 Harmful if inhaled
Acute toxicity, inhalation

Hazard Class

Class IRRITANT Class IRRITANT

Synonyms & References

English

4-Morpholin-4-ylmethylbenzylamine
TIMTEC-BB SBB011151
1-[4-(MORPHOLIN-4-YLMETHYL)PHENYL]METHANAMINE
AKOS BB-8919
4-(4-MORPHOLINYLMETHYL)BENZYLAMINE
4-(MORPHOLINOMETHYL)BENZYLAMINE
BUTTPARK 98\57-94
[4-(morpholin-4-ylmethyl)phenyl]methanamine
4-MORPHOLIN-4-YLMETHYL-BENZYLAMINE
Benzenemethanamine,4-(4-morpholinylmethyl)-
(4-(Morpholinomethyl)phenyl)methanamine
4-(morpholin-4-ylmethyl)benzylamine
{4-[(morpholin-4-yl)methyl]phenyl}methanamine
[4-(morpholinomethyl)phenyl]methanamine
[4-(morpholin-4-ylmethyl)phenyl]methylamine
4-(4-Morpholinylmethyl)benzenemethanamine (ACI)
4-(4-Aminomethylbenzyl)morpholine
4-(Morpholin-4-ylmethyl)benzylamine
4-(Morpholinomethyl)benzylamine
[4-(Morpholin-4-ylmethyl)phenyl]methanamine
[4-(Morpholinomethyl)phenyl]methanamine
[4-[(Morpholin-4-yl)methyl]phenyl]methanamine
1-{4-[(morpholin-4-yl)methyl]phenyl}methanamine
AKOS000264572
4-(morpholinomethyl)benzylamine
4-(morpholinomethyl)phenylmethylamine
FS-2055
OTMQHFNPBREFIL-UHFFFAOYSA-N
4-[4-(Aminomethyl)benzyl]morpholine
SDCCGMLS-0066080.P001
SCHEMBL113089

MDL Number

MFCD05664410

Customs Code

2934999090

FAQ

What are the physical and chemical properties of 4-Morpholin-4-ylmethylbenzylamine (CAS: 91271-84-0)?

4-Morpholin-4-ylmethylbenzylamine is a white or off-white crystalline solid with a molecular weight of approximately 238.36 g/mol. It is slightly soluble in water and has good solubility in organic solvents like ethanol and dimethylformamide. The compound is known for its moderate basicity and reactivity with acidic compounds. It is stable under normal conditions but should be stored in a cool, dark place away from strong acids and bases.

How is 4-Morpholin-4-ylmethylbenzylamine (CAS: 91271-84-0) typically synthesized?

4-Morpholin-4-ylmethylbenzylamine is typically synthesized via the coupling of 4-bromobenzylamine with morpholine in the presence of a suitable base such as triethylamine. The reaction is usually carried out in anhydrous conditions to minimize side reactions. The yield is typically around 70-80%, and the product can be purified by recrystallization from ethanol.

What industries use 4-Morpholin-4-ylmethylbenzylamine (CAS: 91271-84-0)?

4-Morpholin-4-ylmethylbenzylamine is primarily used in the pharmaceutical industry for the synthesis of certain drugs. It is also utilized in the polymer industry for modifying the properties of polymer materials, and in the sensor industry for developing gas sensors. In the semiconductor industry, it can be used as a precursor in the fabrication of electronic materials.

What precautions should be taken when handling 4-Morpholin-4-ylmethylbenzylamine (CAS: 91271-84-0)?

When handling 4-Morpholin-4-ylmethylbenzylamine, it is important to wear appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat. The compound should be stored in a cool, dry place away from direct sunlight. Inhalation and skin contact should be avoided, and the use of a fume hood is recommended during handling. In the event of a spill, it should be cleaned up using appropriate methods, and the Safety Data Sheet (SDS) should be consulted for further guidance.