Veliparib dihydrochloride

Basic Information

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CAS Number

912445-05-7

Molecular Formula

C13H18Cl2N4O

Molecular Weight

280.76 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Amines

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Dyes and Pigments Organic Dyes

Fine Chemicals Surfactants Anionic Surfactants

Agricultural Chemicals Pesticides Herbicides

Basic Physical Properties

SMILES

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CC1(CCCN1)C2=NC3=C(C=CC=C3N2)C(=O)N.Cl.Cl

InChI

InChI=1S/C13H16N4O.2ClH/c1-13(6-3-7-15-13)12-16-9-5-2-4-8(11(14)18)10(9)17-12;;/h2,4-5,15H,3,6-7H2,1H3,(H2,14,18)(H,16,17);2*1H/t13-;;/m1../s1

InChIKey

DSBSVDCHFMEYBX-FFXKMJQXSA-N

LogP

1.6822

Topological Polar Surface Area

83.80000000000001 Å²

Hydrogen Bond Donor/Acceptor

4 / 5

Complexity

348

Synonyms & References

English

ABT888
(R)-2-(2-Methylpyrrolidin-2-yl)-1H-benzo[d]imidazole-4-carboxamide dihydrochloride
2-[(2R)-2-methylpyrrolidin-2-yl]-1H-benzimidazole-4-carboxamide,dihydrochloride
2-[(2R)-2-Methylpyrrolidin-2-yl]-1H-benzimidazole-7-carboxamide dihydrochloride
ABT-888
ABT-888 (hydrochloride)
ABT888 2HCl
ABT-888 2HCl
Veliparib (dihydrochloride)
ABT888 dihydrochloride
ABT-888 dihydrochloride
Veliparib dihydrochloride
1H-Benzimidazole-4-carboxamide, 2-[(2R)-2-methyl-2-pyrrolidinyl]-, dihydrochloride (9CI)
(R)-2-(2-Methylpyrrolidin-2-yl)-1H-benimidazole-4-carboxamide dihydrochloride (VELIPARIB)
Veliparib (ABT-888)
ABT888 hydrochloride
J-505212
SCHEMBL19328639
SB16479
HY-10130
DTXSID30670432
AS-17023
Veliparib 2HCl; ABT-888
912445-05-7
HMS3295I11
SCHEMBL2368883
AKOS030231611
Veliparib (ABT-888 hydrochloride)
2-[(2R)-2-Methylpyrrolidin-2-yl]-1H-benzimidazole-4-carboxamide--hydrogen chloride (1/2)
2-((2r)-2-methyl-2-pyrrolidinyl)-1h-benzimidazole-4-carboxamide dihydrochloride
MFCD12407402

MDL Number

MFCD12407402

FAQ

What is Veliparib dihydrochloride (CAS: 912445-05-7)?

Veliparib dihydrochloride is a poly(ADP-ribose) polymerase (PARP) inhibitor with a chemical formula of C25H23N7O7·2HCl. It is used in the treatment of certain types of cancer and is currently in clinical development for other conditions.

What are the main uses of Veliparib dihydrochloride (CAS: 912445-05-7)?

Veliparib dihydrochloride is primarily used as a PARP inhibitor in the treatment of advanced or recurrent ovarian cancer, and it is also under investigation for use in other types of cancer and various research applications.

Is Veliparib dihydrochloride (CAS: 912445-05-7) safe?

Veliparib dihydrochloride is generally considered safe when used under the guidance of a healthcare professional. However, it may cause side effects such as nausea, fatigue, and anemia. Users should follow all prescribed dosages and precautions to ensure safety.

How should Veliparib dihydrochloride (CAS: 912445-05-7) be stored?

Veliparib dihydrochloride should be stored at a temperature between 15°C and 30°C (59°F and 86°F) in a tightly sealed container, away from direct light and moisture. It should be kept out of reach of children and pets.