Semaglutide | CAS No. 910463-68-2

Semaglutide

Basic Information

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CAS Number

910463-68-2

Molecular Formula

C187H291N45O59

Molecular Weight

4113.58 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Ethers

Basic Chemical Raw Materials Organic Chemicals Amines

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Dyes and Pigments Organic Dyes

Fine Chemicals Surfactants Anionic Surfactants

Laboratory Chemicals Research Chemicals Biochemical Reagents

Basic Physical Properties

SMILES

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CCC(C)C(C(=O)NC(C)C(=O)NC(CC1=CNC2=CC=CC=C21)C(=O)NC(CC(C)C)C(=O)NC(C(C)C)C(=O)NC(CCCNC(=N)N)C(=O)NCC(=O)NC(CCCNC(=N)N)C(=O)NCC(=O)O)NC(=O)C(CC3=CC=CC=C3)NC(=O)C(CCC(=O)O)NC(=O)C(CCCCNC(=O)COCCOCCNC(=O)COCCOCCNC(=O)CCC(C(=O)O)NC(=O)CCCCCCCCCCCCCCCCC(=O)O)NC(=O)C(C)NC(=O)C(C)NC(=O)C(CCC(=O)N)NC(=O)CNC(=O)C(CCC(=O)O)NC(=O)C(CC(C)C)NC(=O)C(CC4=CC=C(C=C4)O)NC(=O)C(CO)NC(=O)C(CO)NC(=O)C(C(C)C)NC(=O)C(CC(=O)O)NC(=O)C(CO)NC(=O)C(C(C)O)NC(=O)C(CC5=CC=CC=C5)NC(=O)C(C(C)O)NC(=O)CNC(=O)C(CCC(=O)O)NC(=O)C(C)(C)NC(=O)C(CC6=CN=CN6)N

InChI

1S/C187H291N45O59/c1-18-105(10)154(180(282)208-108(13)159(261)216-133(86-114-89-200-119-50-40-39-49-117(114)119)170(272)218-129(82-102(4)5)171(273)228-152(103(6)7)178(280)215-121(53-44-72-199-186(192)193)162(264)201-91-141(242)209-120(52-43-71-198-185(190)191)161(263)204-94-151(257)258)230-172(274)131(83-111-45-33-31-34-46-111)219-167(269)126(64-69-149(253)254)214-166(268)122(51-41-42-70-195-144(245)98-290-79-78-289-76-74-197-145(246)99-291-80-77-288-75-73-196-139(240)66-61-127(183(285)286)211-140(241)54-37-29-27-25-23-21-19-20-22-24-26-28-30-38-55-146(247)248)212-158(260)107(12)206-157(259)106(11)207-165(267)125(60-65-138(189)239)210-142(243)92-202-163(265)123(62-67-147(249)250)213-168(270)128(81-101(2)3)217-169(271)130(85-113-56-58-116(238)59-57-113)220-175(277)135(95-233)223-177(279)137(97-235)224-179(281)153(104(8)9)229-174(276)134(88-150(255)256)221-176(278)136(96-234)225-182(284)156(110(15)237)231-173(275)132(84-112-47-35-32-36-48-112)222-181(283)155(109(14)236)227-143(244)93-203-164(266)124(63-68-148(251)252)226-184(287)187(16,17)232-160(262)118(188)87-115-90-194-100-205-115/h31-36,39-40,45-50,56-59,89-90,100-110,118,120-137,152-156,200,233-238H,18-30,37-38,41-44,51-55,60-88,91-99,188H2,1-17H3,(H2,189,239)(H,194,205)(H,195,245)(H,196,240)(H,197,246)(H,201,264)(H,202,265)(H,203,266)(H,204,263)(H,206,259)(H,207,267)(H,208,282)(H,209,242)(H,210,243)(H,211,241)(H,212,260)(H,213,270)(H,214,268)(H,215,280)(H,216,261)(H,217,271)(H,218,272)(H,219,269)(H,220,277)(H,221,278)(H,222,283)(H,223,279)(H,224,281)(H,225,284)(H,226,287)(H,227,244)(H,228,273)(H,229,276)(H,230,274)(H,231,275)(H,232,262)(H,247,248)(H,249,250)(H,251,252)(H,253,254)(H,255,256)(H,257,258)(H,285,286)(H4,190,191,198)(H4,192,193,199)/t105-,106-,107-,108-,109+,110+,118-,120-,121-,122-,123-,124-,125-,126-,127+,128-,129-,130-,131-,132-,133-,134-,135-,136-,137-,152-,153-,154-,155-,156-/m0/s1

InChIKey

DLSWIYLPEUIQAV-CCUURXOWSA-N

LogP

-11.627860000000217

Topological Polar Surface Area

1646.179999999998 Å²

Hydrogen Bond Donor/Acceptor

61 / 104

Complexity

9590

Synonyms & References

English

索玛鲁肽
Sermaglutide
Semaglutide
Unknown (acetate)
NN9535
Semaglutide [USAN:INN]
Ozempic
NN 9535
Rybelsus (oral semaglutide)
GTPL9724
Ozempic (injectable semaglutide)
semaglutide/Sermaglutide
Glycine
L-histidyl-2-methylalanyl-L-a-glutamylglycyl-L-threonyl-L-phenylalanyl-L-threonyl-L-seryl-L-a-aspartyl-L-valyl-L-seryl-L-seryl-L-tyrosyl-L-leucyl-L-a-glutamylglycyl-L-glutaminyl-L-alanyl-L-alanyl-N6-[N-(17-carboxy-1-oxoheptadecyl)-L-?-glutamyl-2-[2-(2-aminoethoxy)ethoxy]acetyl-2-[2-(2-aminoethoxy)ethoxy]acetyl]-L-lysyl-L-a-glutamyl-L-phenylalanyl-L-isoleucyl-L-alanyl-L-tryptophyl-L-leucyl-L-valyl-L-arginylglycyl-L-arginyl- (ACI)
NN1535 LAISEMA COMPONENT SEMAGLUTIDE
NNC-0113-0217
EX-A2424
Rybelsus
DTXSID101027903
NNC0480 0389
Oral Semaglutide
Wegovy
Semaglutide free base
NNC 0113-0217
53AXN4NNHX
CHEBI:167574
A10BJ06
semaglutida
NN-9535
Semaglutide(sodium salt)?
NN1535 ICOSEMA COMPONENT SEMAGLUTIDE

FAQ

What is Semaglutide (CAS: 910463-68-2)?

Semaglutide (CAS: 910463-68-2) is a synthetic glucagon-like peptide-1 (GLP-1) receptor agonist used primarily in the treatment of type 2 diabetes. It has the chemical formula C14H22N2O4S and is characterized by its ability to stimulate insulin secretion, reduce glucagon release, and slow gastric emptying. Semaglutide is known for its high potency and long half-life, making it effective for once-weekly administration.

What are the main uses of Semaglutide (CAS: 910463-68-2)?

Semaglutide (CAS: 910463-68-2) is mainly used as a medication for managing type 2 diabetes by improving blood glucose control. It is also approved for weight management in adults with obesity. In research settings, Semaglutide is studied for its potential in treating other metabolic disorders. Its applications extend to pharmaceutical development due to its unique pharmacological profile.

Is Semaglutide (CAS: 910463-68-2) safe?

Semaglutide (CAS: 910463-68-2) is generally considered safe when used as directed, but it may cause side effects such as nausea, vomiting, and diarrhea. It is important to follow medical guidelines and consult healthcare professionals for proper handling. Safety standards ensure that Semaglutide is produced and used under controlled conditions to minimize risks to human health and the environment.

How should Semaglutide (CAS: 910463-68-2) be stored?

Semaglutide (CAS: 910463-68-2) should be stored in a cool, dry place away from direct light. It is typically kept at a temperature between 2°C to 8°C (refrigerated) during transport and storage. For stability, it should be protected from moisture and stored in airtight, light-resistant containers. Always check the specific storage instructions on the product label.