3-Hydroxy-2H-indol-2-one

Basic Information

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CAS Number

91-56-5

Molecular Formula

C8H5NO2

Molecular Weight

147.13 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Ketones

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Dyes and Pigments Organic Dyes

Basic Physical Properties

Melting Point

200.0 to 204.0 deg-C

Boiling Point

360.3°C at 760 mmHg

Density

1.3067 (rough estimate)

Water Solubility

Soluble in water (1.9 g/L at 20°C).

Flash Point

220 ºC

Solubility

soluble

Refractive Index

1.4700 (estimate)

SMILES

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O=C1Nc2ccccc2C1=O

InChI

InChI=1S/C8H5NO2/c10-7-5-3-1-2-4-6(5)9-8(7)11/h1-4H,(H,9,10,11)

InChIKey

JXDYKVIHCLTXOP-UHFFFAOYSA-N

LogP

0.8213999999999999

Topological Polar Surface Area

46.17 Å²

Hydrogen Bond Donor/Acceptor

1 / 3

Complexity

212

Safety Information

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GHS Hazard Pictograms

H315

H319

H335

Hazard Statement

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

H335 May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation

Hazard Class

Class 6.1(b) Class 6.1(b)

Stability

Stable. Incompatible with strong acids.

Synonyms & References

English

Indoline-2,3-dione
IRSOGLADINEMALEATE
ISATIN, PHARMACEUTICAL GRADE
ISATIN, TECHNICAL GRADE
Isatin, synthesis grade
Isatin, reagent grade
Indole-2,3-dione(Isatin)
Isatin
1H-Indole-2,3-dione
2,3-Indolinedione
ISATIN(RG)
2,3-dihydro-1H-indol-2,3-dione
2,3-INDOLEDIONE
2,3-KETOINDOLINE
2-methopropan-1-ol
indole-2,3-dione
Indoquinone
ISATIC ANHYDRIDE
Isotin
2,3-Dioxo-2,3-dihydroindole
2,3-Diketoindoline
2,3-Dioxoindoline
o-Aminobenzoylformic anhydride
Isatic acid lactam
Isatine
Isatinic acid anhydride
NSC 9262
Pseudoisatin
Tribulin
2,3-dihydro-1H-indole-2,3-dione
2,3-dihydroindole-2,3-dione

MDL Number

MFCD00005718

Customs Code

2933990090

FAQ

What is 3-Hydroxy-2H-indol-2-one (CAS: 91-56-5)?

3-Hydroxy-2H-indol-2-one (CAS: 91-56-5) is a heterocyclic organic compound with the chemical formula C8H7NO2. It is a derivative of indole and exhibits characteristics of a lactone ring, making it a valuable intermediate in chemical synthesis. The compound is typically used in research and industrial applications due to its reactivity and structural versatility.

What are the main uses of 3-Hydroxy-2H-indol-2-one (CAS: 91-56-5)?

3-Hydroxy-2H-indol-2-one (CAS: 91-56-5) is primarily used in pharmaceutical research for the development of drugs targeting neurological and metabolic disorders. It also serves as a key component in the synthesis of various bioactive compounds and is applied in the fragrance and dye industries. Additionally, it is used in organic chemistry research for structural modifications and reaction studies.

Is 3-Hydroxy-2H-indol-2-one (CAS: 91-56-5) safe?

3-Hydroxy-2H-indol-2-one (CAS: 91-56-5) is generally considered safe when handled properly in controlled environments. However, it may cause skin and eye irritation, so appropriate protective measures such as gloves and safety goggles are recommended. Safety standards for handling this compound are in line with general chemical safety protocols, emphasizing proper ventilation and avoidance of inhalation exposure.

How should 3-Hydroxy-2H-indol-2-one (CAS: 91-56-5) be stored?

3-Hydroxy-2H-indol-2-one (CAS: 91-56-5) should be stored in a cool, dry, and dark place, ideally at 2-8°C. It is sensitive to moisture and light, so it should be kept in a sealed container with a desiccant and stored away from direct sunlight. Proper storage ensures its stability and prevents degradation during handling and transportation.