(Hydroxypropyl)methyl Cellulose Phthalate

Basic Information

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CAS Number

9050-31-1

Molecular Formula

C14H16N4

Molecular Weight

240.3 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Amines

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Basic Physical Properties

Melting Point

>145 °C (dec.)

Boiling Point

456.7 °C at 760 mmHg

Density

0.6 g/mL at 25 °C

Flash Point

230 °C

Solubility

H2O: Limited solubility at low pH, soluble at pH ≥4.2.soluble

Refractive Index

1.681

SMILES

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CC(C)CN1C=NC2=C1C3=CC=CC=C3N=C2N

InChI

InChI=1S/C14H16N4/c1-9(2)7-18-8-16-12-13(18)10-5-3-4-6-11(10)17-14(12)15/h3-6,8-9H,7H2,1-2H3,(H2,15,17)

InChIKey

DOUYETYNHWVLEO-UHFFFAOYSA-N

LogP

2.7

Topological Polar Surface Area

56.730000000000004 Å²

Hydrogen Bond Donor/Acceptor

2 / 4

Complexity

294

Synonyms & References

English

NS00006714
CHEBI:36704
Beselna
A845945
1-isobutyl-1H-imidazo [4,5-c]quinolin-4-amine
IMIQUIMOD [VANDF]
MTD-39
NSC369100
BI164576
I0747
1-isobutylimidazo[4,5-c]quinolin-4-amine
1H-Imidazo[4,5-c]quinolin-4-amine, 1-(2-methylpropyl)-
1-(2-methylpropyl)-1H-imidazo[4,5-c]-quinolin-4-amine
IMIQUIMOD
1-isobutyl-1H-imidazo(4,5-c)quinolin-4-amine
(Hydroxypropyl)methyl cellulose phthalate
HMS3747A13
NSC759651
NCGC00070736-02
Zyclara
FT-0602727
Imiquimod, United States Pharmacopeia (USP) Reference Standard
4-Amino-1-isobutyl-1H-imidazo[4,5-c]quinoline
SY017571
1-(2-methylpropyl)-1H-imidazo(4,5-c)quinolin-4-amine
SR-01000611320
IMIQUIMOD (MART.)
Imiquimodum
KS-5218
UNII-P1QW714R7M
1-isobutyl-1H-imidazo[4,5-c]quinolin-4-amine

MDL Number

MFCD00147216

FAQ

What are the physical and chemical properties of (Hydroxypropyl)methyl Cellulose Phthalate (CAS: 9050-31-1)?

(Hydroxypropyl)methyl Cellulose Phthalate (CAS: 9050-31-1) is a semicrystalline polymer with a high molecular weight. It has low solubility in water but dissolves in organic solvents. It is moderately reactive with acidic and basic compounds. Its properties include good film-forming ability and excellent mechanical strength.

How is (Hydroxypropyl)methyl Cellulose Phthalate (CAS: 9050-31-1) typically synthesized?

(Hydroxypropyl)methyl Cellulose Phthalate (CAS: 9050-31-1) is synthesized by the phthalation of cellulose derivatives using phthalic anhydride. Common catalysts include organic acids, and the process involves esterification reactions. The product is purified by precipitation and drying.

What industries use (Hydroxypropyl)methyl Cellulose Phthalate (CAS: 9050-31-1)?

(Hydroxypropyl)methyl Cellulose Phthalate (CAS: 9050-31-1) is widely used in pharmaceuticals for enteric coatings, as a film-forming agent in cosmetics, and in the polymer industry for film and coating applications. It is also utilized in the food industry as a stabilizer and thickener.

What precautions should be taken when handling (Hydroxypropyl)methyl Cellulose Phthalate (CAS: 9050-31-1)?

When handling (Hydroxypropyl)methyl Cellulose Phthalate (CAS: 9050-31-1), use appropriate personal protective equipment (PPE) such as gloves and goggles. Store in a cool, dry place away from heat and sources of ignition. Dispose of waste materials according to local regulations and consult the Safety Data Sheet (SDS) for detailed information on handling and disposal.