Blenoxane | CAS No. 9041-93-4

Blenoxane

Basic Information

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CAS Number

9041-93-4

Molecular Formula

C55H84N17O21S3+

Molecular Weight

1415.55 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Ethers

Basic Chemical Raw Materials Organic Chemicals Amines

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Dyes and Pigments Organic Dyes

Fine Chemicals Surfactants Anionic Surfactants

Laboratory Chemicals Research Chemicals Biochemical Reagents

Basic Physical Properties

Melting Point

197 deg C (dec)

Density

1.1300

Water Solubility

Soluble in water or DMSO

Solubility

H2O: 20 mg/mL

SMILES

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CC1=C(N=C(N=C1N)C(CC(=O)N)NCC(C(=O)N)N)C(=O)NC(C(C2=CN=CN2)OC3C(C(C(C(O3)CO)O)O)OC4C(C(C(C(O4)CO)O)OC(=O)N)O)C(=O)NC(C)C(C(C)C(=O)NC(C(C)O)C(=O)NCCC5=NC(=CS5)C6=NC(=CS6)C(=O)NCCC[S+](C)C)O.OS(=O)(=O)[O-]

InChI

InChI=1S/C55H83N17O21S3.H2O4S/c1-20-33(69-46(72-44(20)58)25(12-31(57)76)64-13-24(56)45(59)82)50(86)71-35(41(26-14-61-19-65-26)91-54-43(39(80)37(78)29(15-73)90-54)92-53-40(81)42(93-55(60)88)38(79)30(16-74)89-53)51(87)66-22(3)36(77)21(2)47(83)70-34(23(4)75)49(85)63-10-8-32-67-28(18-94-32)52-68-27(17-95-52)48(84)62-9-7-11-96(5)6;1-5(2,3)4/h14,17-19,21-25,29-30,34-43,53-54,64,73-75,77-81H,7-13,15-16,56H2,1-6H3,(H13-,57,58,59,60,61,62,63,65,66,69,70,71,72,76,82,83,84,85,86,87,88);(H2,1,2,3,4)/t21?,22?,23?,24?,25?,29-,30+,34?,35?,36?,37+,38+,39-,40-,41?,42-,43-,53+,54-;/m0./s1

InChIKey

WUIABRMSWOKTOF-OCBSMOPSSA-N

LogP

-4.20880

Complexity

2660

Safety Information

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GHS Hazard Pictograms

H351

Hazard Statement

H351 Suspected of causing cancer
Carcinogenicity

Sensitiveness

thermally sensitive

Synonyms & References

English

Bleomycin sulfate
BLENOXANE
BLEO
BLEOMYCIN SULFATE, STREPTOMYCES VERTICILLUS
BLEXANE
Blenmycins
bleomycin,sulfate(salt)
NSC-125066
bleomycin sulfate from streptomyces verticillus
BLEOMYCIN SULFATE CELL CULTURE TESTED
BLEOMYCIN SULFATE, BPC
BLEOMYCIN SULFATE FROM STREPTOMYCES VERT ICILLUS, LYOPH.
Blocamicina
Bleomycin Sulfate, Blenoxane
Bleomycin Sulfate (A mixture of bleomycin sulfate salts)
Blenoxane, Bleo, Blexane
Bleomycin Sulfate (mixture)
Bleomycin (sulfate)
Bleomycin sulfate (Bleo, Blexane, Blenoxane®)
Bleomycin sulphate, Comet assay grade
1.5-2.0 units
BLEMOYCIN SULFATE
BleoMycin Sufate
BLEOMYCIN SULPHATE
3-[[2-[2-[2-[2-[4-[2-[6-Amino-2-[1-(2-amino-2-carbamoyl-ethyl)amino-2-carbamoyl-ethyl]-5-methyl-pyrimidin-4-yl]carbonylamino-3-[3-[4-carbamoyloxy-3,5-dihydroxy-6-(hydroxymethyl)tetrahydropyran-2-yl]ox
3-[[2-[2-[2-[[(2S,3R)-2-[[(2S,3R,4R)-4-[[(2R,3S)-2-[[6-Amino-2-[(1S)-3-amino-1-[[(2R)-2,3-diamino-3-
3-[[2-[2-[2-[2-[4-[2-[6-Amino-2-[1-(2-amino-2-carbamoyl-ethyl)amino-2-carbamoyl-ethyl]-5-methyl-pyrimidin-4-yl]carbonylamino-3-[3-[4-carbamoyloxy-3,5-dihydroxy-6-(hydroxymethyl)tetrahydropyran-2-yl]oxy-4,5-dihydroxy-6-(hydroxymethyl)tetrahydropyran-2-yl]oxy-3-(3H-imidazol-4-yl)propanoyl]amino-3-hydroxy-2-methyl-pentanoyl]amino-3-hydroxy-butanoyl]aminoethyl]-1,3-thiazol-4-yl]-1,3-thiazol-4-yl]carbonylamino]propyl-dimethyl-sulfonium hydrogen sulfate
SR-01000941586
Blexane
Bleomycin sulfate (salt)
Bleomycin sulfate [Bleomycins]

MDL Number

MFCD00070310

FAQ

What is Blenoxane (CAS: 9041-93-4)?

Blenoxane (CAS: 9041-93-4) is a chemotherapy drug classified as an anthracycline antibiotic. Its chemical formula is C21H23NO11, and it appears as a white to off-white powder. It is known for its antineoplastic properties, inhibiting DNA synthesis and RNA transcription in cancer cells, making it effective in treating various malignancies.

What are the main uses of Blenoxane (CAS: 9041-93-4)?

Blenoxane (CAS: 9041-93-4) is primarily used in oncology as a chemotherapy agent. It treats breast cancer, lymphoma, leukemia, and other cancers by targeting rapidly dividing cells. Additionally, it is applied in research for studying antitumor mechanisms and in pharmaceutical development for cancer therapy formulations.

Is Blenoxane (CAS: 9041-93-4) safe?

Blenoxane (CAS: 9041-93-4) is a potent cytotoxic agent, requiring strict safety measures. Handling should be done with protective gloves, goggles, and ventilation to minimize exposure. It is regulated by safety standards like OSHA and EPA, and its use is limited to medical supervision due to potential side effects such as cardiotoxicity and myelosuppression.

How should Blenoxane (CAS: 9041-93-4) be stored?

Blenoxane (CAS: 9041-93-4) should be stored in a cool, dry place at 2-8°C, protected from light. It requires airtight, dark-colored containers to maintain stability and prevent degradation. Avoid exposure to moisture and ensure proper labeling to comply with pharmaceutical storage guidelines.