3,5-Difluorobenzylamine

Basic Information

View in Editor

CAS Number

90390-27-5

Molecular Formula

C7H7F2N

Molecular Weight

143.14 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Amines

Fine Chemicals Specialty Chemicals UV Stabilizers

Agricultural Chemicals Pesticides Herbicides

Electronic Chemicals Semiconductor Materials Etchants

Basic Physical Properties

Boiling Point

184 °C

Density

1.21 g/mL at 25 °C

Refractive Index

n20/D 1.491(lit.)

SMILES

View in Editor

C1=C(C=C(C=C1F)F)CN

InChI

InChI=1S/C7H7F2N/c8-6-1-5(4-10)2-7(9)3-6/h1-3H,4,10H2

InChIKey

VJNGGOMRUHYAMC-UHFFFAOYSA-N

LogP

1.4235

Topological Polar Surface Area

26.02 Å²

Hydrogen Bond Donor/Acceptor

2 / 1

Complexity

97.8

Safety Information

View Safety Information

GHS Hazard Pictograms

H314

Hazard Statement

H314 Causes severe skin burns and eye damage
Skin corrosion/irritation

Hazard Class

Class 8 Class 8

Sensitiveness

Air Sensitive

Synonyms & References

English

3,5-Difluorobenzylamine
Difluorobenzylamine6
2,6-difluorobenzylamine
3,5-Difluorobenzylam
RARECHEM AL BW 0274
(3,5-difluorophenyl)methanamine
3,5-difluorobenzyl amine
Benzenemethanamine, 3,5-difluoro-
1-(3,5-difluorophenyl)methanamine
(3,5-difluorophenyl)methylamine
VJNGGOMRUHYAMC-UHFFFAOYSA-N
3, 5-difluorobenzylamine
PubChem4409
3,5-difluoro-benzylamine
3,5-difluoro-benzyl amine
SBB047766
A
3,5-Difluorobenzenemethanamine (ACI)
(3,5-Difluorophenyl)methanamine
1-(3,5-Difluorophenyl)methanamine
[(3,5-Difluorophenyl)methyl]amine
EN300-33427
AKOS000163830
DTXSID20238146
AB02411
CS-W018264
3,5-Difluorobenzylamine, 96%
MFCD00061244
DTXCID40160637
90390-27-5
CK2422

MDL Number

MFCD00061244

Customs Code

2921499090

FAQ

What are the physical and chemical properties of 3,5-Difluorobenzylamine (CAS: 90390-27-5)?

3,5-Difluorobenzylamine is a colorless or white crystalline solid with a molecular weight of approximately 165.08 g/mol. It is slightly soluble in water but more soluble in organic solvents. It is known for its reactivity, particularly in nucleophilic substitution reactions. Its physical property data include a melting point of 83-85°C and a density of 1.14 g/cm³.

How is 3,5-Difluorobenzylamine (CAS: 90390-27-5) typically synthesized?

3,5-Difluorobenzylamine can be synthesized via a multistep process involving the reaction of 3,5-difluorobenzyl alcohol with ammonia. The synthesis typically involves the use of a suitable catalyst such as potassium hydroxide. The yield can be controlled by optimizing reaction conditions, and the method is known for good selectivity. Literature reports include the use of amination reactions followed by hydrogenation steps.

What industries use 3,5-Difluorobenzylamine (CAS: 90390-27-5)?

3,5-Difluorobenzylamine is used in various industries. It is particularly important in the pharmaceutical industry for the synthesis of certain drug intermediates. It also finds applications in the polymer industry for enhancing the performance of certain materials. Additionally, it is used in the development of sensors and semiconductors due to its chemical reactivity and functional groups.

What precautions should be taken when handling 3,5-Difluorobenzylamine (CAS: 90390-27-5)?

When handling 3,5-Difluorobenzylamine, it is essential to wear appropriate personal protective equipment (PPE) such as gloves, safety goggles, and a lab coat. Work should be conducted in a well-ventilated area or a fume hood. In case of a spill, immediate action should be taken, and the area should be cleaned with appropriate solvents. Safety data sheets (SDS) should be consulted for detailed handling and emergency procedures. Storage should be in a cool, dry place away from direct sunlight and heat sources.