Lysostaphin | CAS No. 9011-93-2

Lysostaphin

Basic Information

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CAS Number

9011-93-2

Molecular Formula

C16H14N2O3

Molecular Weight

282.3 g/mol

EINECS

812-596-7

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Esters

Basic Chemical Raw Materials Organic Chemicals Ethers

Basic Chemical Raw Materials Organic Chemicals Nitriles

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Dyes and Pigments Organic Dyes

Fine Chemicals Surfactants Anionic Surfactants

Agricultural Chemicals Pesticides Herbicides

Laboratory Chemicals Research Chemicals Biochemical Reagents

Basic Physical Properties

Physical State

slightly brown

SMILES

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CCCCCCCCC=CCCCCCCCC(=O)OCC(COC(=O)CCCCCCCC=CCCCCCCCC)OC(=O)CC(C)CCCC(C)CC(=O)OC1=C(C=C(C=C1Cl)COC(=O)N2C=CC3=C2N=CN=C3N(C)C4CN(CCC4C)C(=O)CC#N)Cl

InChI

InChI=1S/C16H14N2O3/c1-20-11-7-10(8-12(9-11)21-2)15-17-14-6-4-3-5-13(14)16(19)18-15/h3-9H,1-2H3,(H,17,18,19)

InChIKey

GGOWAPMNHOQUBZ-UHFFFAOYSA-N

LogP

2.6073000000000004

Topological Polar Surface Area

64.21000000000001 Å²

Hydrogen Bond Donor/Acceptor

1 / 5

Complexity

2150

Safety Information

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Toxicity

LD50 (7-day) in mice, rats (mg/kg): 820, 530 i.v. (Zygmunt)

Synonyms & References

English

Lysostaphin
200443-93-2
1-O-[1,3-bis[[(Z)-octadec-9-enoyl]oxy]propan-2-yl] 9-O-[2,6-dichloro-4-[[4-[[(3R,4R)-1-(2-cyanoacetyl)-4-methylpiperidin-3-yl]-methylamino]pyrrolo[2,3-d]pyrimidine-7-carbonyl]oxymethyl]phenyl] 3,7-dimethylnonanedioate
9011-93-2
1-O-[2, 6-dichloro-4-[[4-[[1-(2-cyanoacetyl)-4-methylpiperidin-3-yl]-methylamino]pyrrolo[2, 3-d]pyrimidine-7-carbonyl]oxymethyl]phenyl] 9-O-[1, 3-di(octadec-9-enoyloxy)propan-2-yl] 3, 7-dimethylnonanedioate
Methyleugenyl PEG-8 dimethicone
58856-93-2
LYSOSTAPHIN
Lysostaphin from Staphylococcus staphylolyticus
lysostaphin from staphylococcus staphy-lolyticus
LYSOSTAPHIN ASEPTICALLY FILLED
LYSOSTAPHIN, STAPHYLOCOCCUS SIMULANS,*RE COMBINANT
LYSOSTAPHIN AFFINITY PURIFIED
LYSOSTAPHIN FROM STAPHYLOCOCCUS STAPHY-L OLYTICUS, ~1 U/MG
glycyl-glycine endopeptidase
Glycyl-glycine Endopeptidase
Ambicin L
E.C. 3.4.24.75
EC 3.4.24.75
Glycyl-glycine endopeptidase

MDL Number

MFCD00131556

EC Number

812-596-7

Customs Code

3507909090

FAQ

What is Lysostaphin (CAS: 9011-93-2)?

Lysostaphin is a bacterial enzyme with peptidoglycan hydrolase activity, obtained from Staphylococcus simulans. It has a molecular formula of C108H184N24O42 and is used in the treatment of staphylococcal infections, especially in managing methicillin-resistant Staphylococcus aureus (MRSA) infections.

What are the main uses of Lysostaphin (CAS: 9011-93-2)?

Lysostaphin is primarily used in the pharmaceutical industry for the treatment of staphylococcal infections. It can be applied topically or systemically to combat infections caused by Staphylococcus species, including MRSA. Additionally, it is used in research for studying bacterial cell wall synthesis and degradation.

Is Lysostaphin (CAS: 9011-93-2) safe?

Lysostaphin is generally considered safe for use in humans. However, it should be used under medical supervision due to potential allergic reactions or other side effects. Proper handling and adherence to safety protocols are recommended to minimize risks.

How should Lysostaphin (CAS: 9011-93-2) be stored?

Lysostaphin should be stored in a dry, cool place, away from direct sunlight and moisture. It should be kept at a temperature not exceeding 20°C. The enzyme should be stored in a tightly sealed container and protected from light to maintain its activity and stability.