Glucagon | CAS No. 9007-92-5

Glucagon

Basic Information

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CAS Number

9007-92-5

Molecular Formula

C153H226ClN43O49S

Molecular Weight

3519.21 g/mol

EINECS

232-708-2

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Amines

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Dyes and Pigments Organic Dyes

Fine Chemicals Surfactants Anionic Surfactants

Laboratory Chemicals Research Chemicals Biochemical Reagents

Basic Physical Properties

SMILES

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CC(C)CC(C(=O)NC(CCSC)C(=O)NC(CC(=O)N)C(=O)NC(C(C)O)C(=O)O)NC(=O)C(CC1=CNC2=CC=CC=C21)NC(=O)C(CCC(=O)N)NC(=O)C(C(C)C)NC(=O)C(CC3=CC=CC=C3)NC(=O)C(CC(=O)O)NC(=O)C(CCC(=O)N)NC(=O)C(C)NC(=O)C(CCCNC(=N)N)NC(=O)C(CCCNC(=N)N)NC(=O)C(CO)NC(=O)C(CC(=O)O)NC(=O)C(CC(C)C)NC(=O)C(CC4=CC=C(C=C4)O)NC(=O)C(CCCCN)NC(=O)C(CO)NC(=O)C(CC5=CC=C(C=C5)O)NC(=O)C(CC(=O)O)NC(=O)C(CO)NC(=O)C(C(C)O)NC(=O)C(CC6=CC=CC=C6)NC(=O)C(C(C)O)NC(=O)CNC(=O)C(CCC(=O)N)NC(=O)C(CO)NC(=O)C(CC7=CN=CN7)N

InChI

InChI=1S/C153H225N43O49S/c1-72(2)52-97(133(226)176-96(47-51-246-11)132(225)184-104(60-115(159)209)143(236)196-123(78(10)203)151(244)245)179-137(230)103(58-83-64-167-89-29-19-18-28-87(83)89)183-131(224)95(43-46-114(158)208)177-148(241)120(74(5)6)194-141(234)101(54-79-24-14-12-15-25-79)182-138(231)105(61-117(211)212)185-130(223)94(42-45-113(157)207)171-124(217)75(7)170-127(220)91(31-22-49-165-152(160)161)172-128(221)92(32-23-50-166-153(162)163)174-146(239)110(69-199)191-140(233)107(63-119(215)216)186-134(227)98(53-73(3)4)178-135(228)99(56-81-33-37-85(204)38-34-81)180-129(222)90(30-20-21-48-154)173-145(238)109(68-198)190-136(229)100(57-82-35-39-86(205)40-36-82)181-139(232)106(62-118(213)214)187-147(240)111(70-200)192-150(243)122(77(9)202)195-142(235)102(55-80-26-16-13-17-27-80)188-149(242)121(76(8)201)193-116(210)66-168-126(219)93(41-44-112(156)206)175-144(237)108(67-197)189-125(218)88(155)59-84-65-164-71-169-84/h12-19,24-29,33-40,64-65,71-78,88,90-111,120-123,167,197-205H,20-23,30-32,41-63,66-70,154-155H2,1-11H3,(H2,156,206)(H2,157,207)(H2,158,208)(H2,159,209)(H,164,169)(H,168,219)(H,170,220)(H,171,217)(H,172,221)(H,173,238)(H,174,239)(H,175,237)(H,176,226)(H,177,241)(H,178,228)(H,179,230)(H,180,222)(H,181,232)(H,182,231)(H,183,224)(H,184,225)(H,185,223)(H,186,227)(H,187,240)(H,188,242)(H,189,218)(H,190,229)(H,191,233)(H,192,243)(H,193,210)(H,194,234)(H,195,235)(H,196,236)(H,211,212)(H,213,214)(H,215,216)(H,244,245)(H4,160,161,165)(H4,162,163,166)/t75-,76+,77+,78+,88-,90-,91-,92-,93-,94-,95-,96-,97-,98-,99-,100-,101-,102-,103-,104-,105-,106-,107-,108-,109-,110-,111-,120-,121-,122-,123-/m0/s1

InChIKey

MASNOZXLGMXCHN-ZLPAWPGGSA-N

LogP

0.39110

Complexity

8160

Synonyms & References

English

Hyperglycemic-glycogenolytic factor
l-l-alpha-aspartyl-l-seryl-l-arginyl-l-arginyl-l-alanyl-l-glutaminyl-l-alpha-a
spartyl-l-phenylalanyl-l-valyl-l-glutaminyl-l-tryptophyl-l-leucyl-l-methionyl-
threonyl-l-seryl-l-alpha-aspartyl-l-tyrosyl-l-seryl-l-lysyl-l-tyrosyl-l-leucy
GLUCAGON HYDROCHLORIDE(HUMAN)
glucagon[pig]
glukagonnovo
his-ser-glu(nh2)-gly-thr-phe-thr-ser-asp-tyr-ser-lys-tyr-leu-asp-ser-arg-arg-a
Glucagon
Glucagon Hydrochloride(Human)
Glucagon, Human
Glucagon RecoMbinant
Glucagonoid
Glukagon
HG-Factor
l-histidyl-l-seryl-l-glutaminylglycyl-l-threonyl-l-phenylalanyl-l-l-threonin
Baqsimi
Hyperglycemic factor
MeSH ID: D005934
Glucagon (Human)
Glucagon HCl
Gvoke KitVial
BAQSIMI
Glucagon (Xenopus laevis)
AKOS040741791
Glucagon, porcine, for bioassay
Glucagon (ox)
glucagon
Gvoke PFS
Glucagon, porcine
HIS-SER-GLU(NH2)-GLY-THR-PHE-THR-SER-ASP-TYR-SER-LYS-TY R-LEU-ASP-SER-ARG-ARG-ALA-GLU(NH2)-ASP-PHE-VAL-GLU(NH2)-TRP-LEU-MET-ASP(NH2)-THR

MDL Number

MFCD03428060

EC Number

232-708-2

FAQ

What are the physical and chemical properties of Glucagon (CAS: 9007-92-5)?

Glucagon (CAS: 9007-92-5) is a crystalline polypeptide hormone. It has a molecular weight of approximately 3479.3 Da. Glucagon is slightly soluble in water and is known for its high reactivity with acids and bases. It is stable under dry conditions but can be degraded by heat and light exposure.

How is Glucagon (CAS: 9007-92-5) typically synthesized?

Glucagon (CAS: 9007-92-5) is typically synthesized via solid-phase peptide synthesis. This involves the stepwise addition of amino acids, with controlled conditions to ensure high selectivity and yield. Commonly used catalysts include t-Boc (tert-butyloxycarbonyl) protecting groups and Fmoc (fluorenylmethoxycarbonyl) chemistry. The final product is then deprotected and purified.

What industries use Glucagon (CAS: 9007-92-5)?

Glucagon (CAS: 9007-92-5) is primarily used in the pharmaceutical industry for treating hypoglycemia. It is also used in research for studying glucose homeostasis and in the development of diabetes management solutions. Additionally, it has applications in the food industry for enhancing the nutritional profile of certain products.

What precautions should be taken when handling Glucagon (CAS: 9007-92-5)?

When handling Glucagon (CAS: 9007-92-5), it is essential to wear appropriate personal protective equipment (PPE), including gloves and lab coat, due to its potential for skin irritation. Use a fume hood for any tasks that may generate aerosols. In case of a spill, immediately clean up using appropriate absorbent materials and dispose of according to local regulations. Always refer to the safety data sheet (SDS) for detailed handling and safety information.