Acthargel | CAS No. 9002-60-2

Acthargel

Basic Information

View in Editor

CAS Number

9002-60-2

Molecular Formula

C207H308N56O58S

Molecular Weight

4541.07 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Amines

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Dyes and Pigments Organic Dyes

Fine Chemicals Surfactants Anionic Surfactants

Laboratory Chemicals Research Chemicals Biochemical Reagents

Basic Physical Properties

Solubility

H2O: 1 mg/mL, clear, colorless

SMILES

View in Editor

CC(C)CC(C(=O)NC(CCC(=O)O)C(=O)NC(CC1=CC=CC=C1)C(=O)O)NC(=O)C2CCCN2C(=O)C(CC3=CC=CC=C3)NC(=O)C(C)NC(=O)C(CCC(=O)O)NC(=O)C(C)NC(=O)C(CO)NC(=O)C(CCC(=O)O)NC(=O)C(CC(=O)O)NC(=O)C(CCC(=O)O)NC(=O)C(C)NC(=O)CNC(=O)C(CC(=O)N)NC(=O)C4CCCN4C(=O)C(CC5=CC=C(C=C5)O)NC(=O)C(C(C)C)NC(=O)C(CCCCN)NC(=O)C(C(C)C)NC(=O)C6CCCN6C(=O)C(CCCNC(=N)N)NC(=O)C(CCCNC(=N)N)NC(=O)C(CCCCN)NC(=O)C(CCCCN)NC(=O)CNC(=O)C(C(C)C)NC(=O)C7CCCN7C(=O)C(CCCCN)NC(=O)CNC(=O)C(CC8=CNC9=CC=CC=C98)NC(=O)C(CCCNC(=N)N)NC(=O)C(CC1=CC=CC=C1)NC(=O)C(CC1=CN=CN1)NC(=O)C(CCC(=O)O)NC(=O)C(CCSC)NC(=O)C(CO)NC(=O)C(CC1=CC=C(C=C1)O)NC(=O)C(CO)N

InChI

1S/C207H308N56O58S/c1-108(2)89-140(186(302)240-135(69-74-163(279)280)182(298)254-149(204(320)321)94-117-43-20-15-21-44-117)250-193(309)152-54-35-86-262(152)202(318)147(92-116-41-18-14-19-42-116)252-171(287)114(11)230-175(291)132(66-71-160(273)274)234-170(286)113(10)231-191(307)150(105-265)255-183(299)136(70-75-164(281)282)241-190(306)146(98-165(283)284)249-180(296)133(67-72-161(275)276)235-169(285)112(9)229-157(270)101-225-174(290)145(97-156(213)269)251-194(310)153-55-36-87-263(153)203(319)148(93-119-60-64-123(268)65-61-119)253-199(315)167(110(5)6)257-185(301)129(49-26-30-79-210)243-198(314)168(111(7)8)259-196(312)155-57-38-85-261(155)201(317)139(53-34-83-223-207(218)219)244-178(294)130(51-32-81-221-205(214)215)237-177(293)128(48-25-29-78-209)236-176(292)127(47-24-28-77-208)232-158(271)103-227-197(313)166(109(3)4)258-195(311)154-56-37-84-260(154)200(316)138(50-27-31-80-211)233-159(272)102-226-173(289)143(95-120-99-224-126-46-23-22-45-124(120)126)247-179(295)131(52-33-82-222-206(216)217)238-187(303)142(90-115-39-16-13-17-40-115)246-189(305)144(96-121-100-220-107-228-121)248-181(297)134(68-73-162(277)278)239-184(300)137(76-88-322-12)242-192(308)151(106-266)256-188(304)141(245-172(288)125(212)104-264)91-118-58-62-122(267)63-59-118/h13-23,39-46,58-65,99-100,107-114,125,127-155,166-168,224,264-268H,24-38,47-57,66-98,101-106,208-212H2,1-12H3,(H2,213,269)(H,220,228)(H,225,290)(H,226,289)(H,227,313)(H,229,270)(H,230,291)(H,231,307)(H,232,271)(H,233,272)(H,234,286)(H,235,285)(H,236,292)(H,237,293)(H,238,303)(H,239,300)(H,240,302)(H,241,306)(H,242,308)(H,243,314)(H,244,294)(H,245,288)(H,246,305)(H,247,295)(H,248,297)(H,249,296)(H,250,309)(H,251,310)(H,252,287)(H,253,315)(H,254,298)(H,255,299)(H,256,304)(H,257,301)(H,258,311)(H,259,312)(H,273,274)(H,275,276)(H,277,278)(H,279,280)(H,281,282)(H,283,284)(H,320,321)(H4,214,215,221)(H4,216,217,222)(H4,218,219,223)/t112-,113-,114-,125-,127-,128-,129-,130-,131-,132-,133-,134-,135-,136-,137-,138-,139-,140-,141-,142-,143-,144-,145-,146-,147-,148-,149-,150-,151-,152-,153-,154-,155-,166-,167-,168-/m0/s1

InChIKey

IDLFZVILOHSSID-OVLDLUHVSA-N

LogP

5.65470

Topological Polar Surface Area

1836.2499999999975 Å²

Hydrogen Bond Donor/Acceptor

72 / 114

Complexity

11200

Synonyms & References

English

Corticotropin
Adrendcorticotrophic hormone
adrenocorticotropic hormone
Cortrophin
Corticotrophin
Corticotrophine
Corticotrofina
Acthargel
Corticotrophinum
beta-Corticotropin
Adrenocorticotrophin
H.P. Acthar gel
Purified Cortrophin gel
Corticotropin [USP:INN]
BDBM82408
SYSMEHFRWGKPVGKKRRPVKVYPDGAEDQLAEAFPLEF
DA-50244
DA-59356
beta-Corticotropin (swine)
25-Asp-30-Gln-corticotropin porcine
NCGC00167127-01
ACTH-(1-39)
CAS_12279-41-3
alpha1-39-Corticotropin (swine), 25-L-aspartic acid-30-L-glutamine
Adrenocorticotropin
UNII-K0U68Q2TXA
12427-33-7
9002-60-2
ACTH (1-39)
K0U68Q2TXA
corticotropin

FAQ

What is Acthargel (CAS: 9002-60-2)?

Acthargel (CAS: 9002-60-2) is a pharmaceutical preparation, typically a gel form of adrenocorticotropic hormone (ACTH), used in veterinary medicine to treat conditions such as adrenal insufficiency and chronic dermatitis in animals.

What are the main uses of Acthargel (CAS: 9002-60-2)?

Acthargel (CAS: 9002-60-2) is primarily used in veterinary medicine to treat adrenal insufficiency, chronic dermatitis, and other conditions requiring hormone supplementation in animals.

Is Acthargel (CAS: 9002-60-2) safe?

Acthargel (CAS: 9002-60-2) is generally safe when used as directed by a veterinarian, but it can cause side effects such as hyperglycemia and hypernatremia. Users should follow safety guidelines and consult a veterinarian for proper dosing and monitoring.

How should Acthargel (CAS: 9002-60-2) be stored?

Acthargel (CAS: 9002-60-2) should be stored in a cool, dry place away from direct sunlight and heat. It should be kept at a temperature not exceeding 25°C (77°F) and in its original packaging to maintain its effectiveness and stability.