Lysozyme | CAS No. 9001-63-2

Lysozyme

Basic Information

CAS Number

9001-63-2

Molecular Formula

C99H159N37O23

Molecular Weight

0 g/mol

AD

Basic Physical Properties

CCC(C)C(C(=O)NC(CCCNC(=N)N)C(=O)NC(C)C(=O)NC(CC1=CNC2=CC=CC=C21)C(=O)NC(C(C)C)C(=O)NC(C)C(=O)NC(CC3=CNC4=CC=CC=C43)C(=O)NC(CCCNC(=N)N)C(=O)NC(CC(=O)N)C(=O)NC(CCCNC(=N)N)C(=O)O)NC(=O)CNC(=O)C(CCC(=O)N)NC(=O)C5CCCN5C(=O)C(CC(=O)O)NC(=O)C(CCCNC(=N)N)NC(=O)C(C(C)C)NC(=O)C(C(C)C)NC(=O)C(CCCNC(=N)N)N

InChI

InChI=1S/C99H159N37O23/c1-11-50(8)77(132-72(139)46-120-81(145)63(32-33-70(101)137)124-88(152)69-31-21-39-136(69)93(157)68(43-73(140)141)131-84(148)62(29-19-37-116-98(109)110)125-90(154)75(48(4)5)135-91(155)76(49(6)7)133-80(144)57(100)24-16-34-113-95(103)104)92(156)126-60(27-17-35-114-96(105)106)82(146)121-51(9)78(142)129-66(41-54-45-119-59-26-15-13-23-56(54)59)87(151)134-74(47(2)3)89(153)122-52(10)79(143)128-65(40-53-44-118-58-25-14-12-22-55(53)58)85(149)123-61(28-18-36-115-97(107)108)83(147)130-67(42-71(102)138)86(150)127-64(94(158)159)30-20-38-117-99(111)112/h12-15,22-23,25-26,44-45,47-52,57,60-69,74-77,118-119H,11,16-21,24,27-43,46,100H2,1-10H3,(H2,101,137)(H2,102,138)(H,120,145)(H,121,146)(H,122,153)(H,123,149)(H,124,152)(H,125,154)(H,126,156)(H,127,150)(H,128,143)(H,129,142)(H,130,147)(H,131,148)(H,132,139)(H,133,144)(H,134,151)(H,135,155)(H,140,141)(H,158,159)(H4,103,104,113)(H4,105,106,114)(H4,107,108,115)(H4,109,110,116)(H4,111,112,117)/t50-,51-,52-,57-,60-,61-,62-,63-,64-,65-,66-,67-,68-,69-,74-,75-,76-,77-/m0/s1

InChIKey

ZJCXKXFAOCLSRV-RYLVIXIQSA-N

LogP

5.45920

Topological Polar Surface Area

1013.7900000000002 Ų

Hydrogen Bond Donor/Acceptor

46 / 60

Complexity

5020

Safety Information

View Safety Information

Stability

Stable. Incompatible with strong oxidizing agents.

Synonyms & References

English

  • lysozyme from human neutrophils
  • lysosyme chloride
  • Lysozyme, Human Neutrophil
  • mucopeptide
  • Lysozyme (hen egg white)
  • EGG WHITE BACTERIOLYSIN
  • Lysozyme
  • Muramidase
  • HL18
  • Lysozyme chloride
  • Lysozyme derived-peptide
  • NH2-Arg-Val-Val-Arg-Asp-Pro-Gln-Gly-Ile-Arg-Ala-Trp-Val-Ala-Trp-Arg-Asn-Arg-COOH
  • Peptidoglykan-N-Acetylmuramoylhydrolase
  • RVVRDPQGIRAWVAWRNR
  • Mucopeptide N-acetylmuramoylhydrolase
  • globulin g
  • lysozyme g
  • mucopeptide glucohydrolase
  • n,o-diacetylmuramidase
  • 1,4-N-Acetylmuramidase
  • Delvozyme
  • Globulin G1
  • Lydium-KLP
  • Peptidoglycan N-acetylmuramoylhydrolase
  • 1,4-β-N-Acetylmuramidase
  • 100940
  • Delvozyme L
  • E.C. 3.2.1.17
  • Globulin G
  • KLP 602
  • LumiVida

MDL Number

MFCD00131557

Customs Code

3507909000

FAQ

What are the physical and chemical properties of Lysozyme (CAS: 9001-63-2)?

Lysozyme (CAS: 9001-63-2) is a protein with a molecular weight of approximately 14,300 Da. It is highly soluble in water but less soluble in organic solvents. Lysozyme exhibits strong reactivity towards bacterial cell walls, cleaving their peptidoglycan layers. This enzyme crystallizes in the monoclinic system and is known for its antimicrobial activity.

How is Lysozyme (CAS: 9001-63-2) typically synthesized?

Lysozyme (CAS: 9001-63-2) is usually synthesized through bacterial fermentation. The process involves culturing a strain of *Corynebacterium* sp., such as *Corynebacterium glutamicum*, under optimal conditions. The enzyme can also be produced by genetic engineering, where the lysozyme gene is introduced into host cells for expression.

What industries use Lysozyme (CAS: 9001-63-2)?

Lysozyme (CAS: 9001-63-2) finds applications in the pharmaceutical industry, particularly in the production of eye drops and nasal sprays for its antimicrobial properties. It is also used in the food industry as a natural preservative, in the cosmetics industry for its skin-benefiting effects, and in biotechnology for its ability to break down bacterial cell walls.

What precautions should be taken when handling Lysozyme (CAS: 9001-63-2)?

Handling Lysozyme (CAS: 9001-63-2) requires caution due to its biological nature. Always wear gloves and a lab coat. Work in a fume hood to avoid inhalation. If a spill occurs, dispose of it according to the Material Safety Data Sheet (MSDS) guidelines. Keep the compound away from high temperatures and direct sunlight. Refer to the SDS for detailed safety information.

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